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Improvement of imaging quality has the potential to visualize previously unseen building blocks of the brain and is therefore one of the great challenges in neuroscience. Rapid development of new tissue clearing techniques in recent years have attempted to solve imaging compromises in thick brain samples, particularly for high resolution optical microscopy, where the clearing medium needs to match
The concept of circular economy has peaked in both popular and scientific discussion in the past few years. Notwithstanding, no specific definition for circularity in the context of existing buildings is available. This research details a framework of circular economy in the built environment, focusing on existing buildings. The paper employs a systematic literature review on circular economy with
A pre-requisite to reach the EU 2030 and beyond targets is a significantly increased ambition among property owners regarding energy-efficient refurbishments. The Swedish Energy Agency and the National Board of Housing, Building and Planning are on the Swedish government assignment developing a strategy with policy instruments to increase energy-efficiency oriented renovation. In order to design t
The development of environmental certification schemes has increased rapidly during the last twenty years and are often used as benchmarks during design of new buildings or reconstruction. However, for management of our existing buildings the members of Sweden Green Building Council request for clear guidelines and a certification scheme. Therefore, a new certification scheme called Miljöbyggnad i
As the building construction industry accounts for a large part of the ecological burden, sustainable construction processes are very important for achieving sustainable communities. Construction is often a linear process, where different actors act at different stages of the process. In this process there are critical borderlines where the information is to be transferred from one actor to anothe
This study explored factors associated with interest in taking PrEP among men who have sex with men (MSM) attending HIV testing venues in Sweden. Data from 658 HIV-negative respondents, surveyed by a questionnaire at six sites, were analyzed descriptively and by univariable and multivariable logistic regression. A total of 453 (68.8%) of the respondents expressed interest in taking PrEP. Reporting
As a result of the energy performance of the buildings directive (EPBD 2010), the requirements have been gradually tightened in the Swedish building regulations. For the purpose of the directive to be realized, it is becoming increasingly important to ensure that buildings actually live up to the minimum rules laid down in the Swedish Building Regulations (BBR) or more ambitious requirements impos
With the increasing global awareness about the impacts of climate change on the built environments, the need for improving the climate resilience of buildings is being more acknowledged. Despite the high number of relevant studies, there is a lack of frameworks to assess the resiliency of buildings and urban areas. This study presents a multi-objective framework to optimize the form of buildings a
Rituximab is a pioneering anti-CD20 monoclonal antibody that became the first-line drug used in immunotherapy of B-cell malignancies over the last twenty years. Rituximab activates the complement system in vitro, but there is an ongoing debate on the exact role of this effector mechanism in therapeutic effect. Results of both in vitro and in vivo studies are model-dependent and preclude clear clin
The COVID-19 pandemic has raised awareness of the urgent need to improve the design of health systems, as well as the practical implementation of new strategies and technical solutions to better prepare for future pandemics. These preparations must also consider harms secondary to the pandemic, including the resulting effects on antimicrobial resistance (AMR). While drug-resistant infections pose
CALIFA is the high efficiency and energy resolution calorimeter for the R3B experiment at FAIR, intended for detecting high energy charged particles and γ-rays in inverse kinematics direct reactions. It surrounds the reaction target in a segmented configuration of Barrel and Forward End-Cap pieces. The CALIFA Barrel consists of 1952 detection units made of CsI(Tl) long-shaped scintillator crystals
We measured absolute cross sections for neutron transfer channels populated in the Rb94+Pb208 binary reaction. Cross sections have been extracted identifying directly the lead isotopes with the high efficiency MINIBALL γ-ray array coupled to a particle detector combined with a radioactive Rb94 beam delivered at Elab=6.2 MeV/nucleon by the HIE-ISOLDE facility. We observed sizable cross sections in
We present direct photon-hadron correlations in 200 GeV/A Au+Au, d+Au, and p+p collisions, for direct photon pT from 5-12 GeV/c, collected by the PHENIX Collaboration in the years from 2006 to 2011. We observe no significant modification of jet fragmentation in d+Au collisions, indicating that cold nuclear matter effects are small or absent. Hadrons carrying a large fraction of the quark's momentu
The measurements of the (anti)deuteron elliptic flow (v2) and the first measurements of triangular flow (v3) in Pb-Pb collisions at a center-of-mass energy per nucleon-nucleon collision sNN = 5.02 TeV are presented. A mass ordering at low transverse momentum (pT) is observed when comparing these measurements with those of other identified hadrons, as expected from relativistic hydrodynamics. The m
Hanbury Brown-Twiss interferometry (HBT) provides crucial insights into both the space-time structure and the momentum-space evolution of ultrarelativistic nuclear collisions at freeze-out. In particular, the dependence of the HBT radii on the transverse pair momentum KT and the system charged multiplicity dNch/dη may reflect the mechanisms driving collective behavior in small systems. This paper
This paper discusses the problem of testing the performance of the adaptation layer in a self-adaptive system. The problem is notoriously hard, due to the high degree of uncertainty and variability inherent in an adaptive software application. In particular, providing any type of formal guarantee for this problem is extremely difficult. In this paper we propose the use of a rigorous probabilistic
Background: Breast compression in mammography is important but is a source of discomfort and has been linked to screening non-attendance. Reducing compression has little effect on breast thickness, and likely little effect on image quality, due to force being absorbed in the stiff juxta thoracic area instead of in the central breast. Purpose: To investigate whether a flexible compression plate can
Background: Alzheimer's disease co-pathology is common in dementia with Lewy bodies and Parkinson's disease with dementia (Lewy body disease) and can reliably be detected with positron emission tomography (PET) or cerebrospinal fluid (CSF) biomarkers. Recently developed blood biomarkers are more accessible and less expensive alternatives. Objective: To investigate if plasma phospho-tau217 and phos
Children's early engagement in design of outdoor spaces can form the basis of later attitudes and responsible action for sustainability. The present study is part of a participatory action research project in an urban multi-ethnic preschool in Sweden, involving children, parents, preschool staff and management with a focus on improving the preschool playground. The methodology involved children ta
