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The possibilities with monoclonal antibodies to be used as drugs against several diseases is of great interest to many pharmaceutical companies. However, efficient production is hindered by advanced and difficult purification steps in the downstream processing. Chromatographic systems have proven to be a powerful methodology promoting high purity, nevertheless associated with high costs. Therefore
Curitiba is the capital of the state of Paraná, in the south of Brazil. One of the main environmental issues Curitiba faces today is related to flooding and cloudburst events. They are caused not only due to climate change but also due to the piping of many rivers, the pollution on the water systems and the irregular settlements around the floodplains. The rivers that were once part of the cultu
Syftet med denna studie vara att undersöka den högkänsliga personens subjektiva upplevelser av livet innan- och efter insikten om personlighetsdraget. Tillkommande frågeställningar som studerades, var även de positiva och negativa aspekterna av personlighetsdraget. Studiens metodologiska utgångspunkt var av den kvalitativa innehållsanalysen. Intervjuer hölls med sju deltagare som upplevde sig själThe purpose of this study was to examine the highly sensitives persons subjective experiences in life before- and after the knowledge about the personality character. Additional questions also studied the positive and negative aspects of the highly sensitive person. The studies methodological framework is based on the qualitative content analysis. The interviews where held with seven participants
During this thesis, work has been done towards realizing a short-wave infrared (SWIR) laser source based on optical parametric amplification. It is planned that this setup should be able to produce few-cycle laser pulses at 2μm with a stable carrier-envelope phase (CEP). This will be done by using various nonlinear processes to convert the output from a 1030-nm, 200 kHz laser source, based on Yb-d
Enligt Trafikverkets siffror ökade utsläppen av växthusgaser från transportsektorn med 0,5 % under 2018 samtidigt som de måste minska med 8 för att nå de uppsatta målen. Ökningen berodde främst på en ökad lastbilstrafik. Det krävs flera lösningar för att nå detta mål. Detta arbete har undersökt om batterielektriska lastbilar kan vara en god lösning för emissionsfria transporter redan idag inom visAccording to the Swedish transport administration the emissions from the transport sector has increased by 0,5 % in 2018 compared to 2017, which is mainly due to an increase in truck traffic. To reach the goals set for the transport sector the emissions must be reduced by 8 % annually. Several solutions are needed to reach this goal. This work has investigated if battery electric trucks can be a g
In order to construct more efficient and environmentally friendly fuels, knowledgeabout the combustion process of the fuels needs to be expanded. This can be doneby running simulations in computational fluid dynamics. In order to efficiently runsimulations, reduced kinetic mechanisms of lesser complexity are used. Increasing theaccuracy and knowledge of the chemical reactions involved in these mec
The surge in revenue from real-time auctions for online display advertisement has spurred great research interest into how to design optimal mechanisms for these auctions, with respect to both buyers and sellers. This thesis focuses on some recent proposals on how to modify the Vickrey auction, which has been dominating the world of real-time auctions for the past decade, in order to better accomm
This thesis evaluates four of the most popular methods for combining time series forecasts. One aspect that is often overlooked in the literature is the choice of which forecasts to include in a forecast combination. The focus here, is to investigate the variability in forecast accuracy that occurs between all distinct subsets from a fixed set of eleven individual forecasting models that a combina
The aim of this Project is to investigate the evolution of the violin concerto, using the example of the Mozart violin concerto nº 5 and Tchaikovsky violin concerto op 35. After the comparison of these two important concertos, the aim is to know more about each of them and to observe the evolution experimented. The methods that I used are the scores of the concertos which make possible to do a mus
Som musiker är instuderingen av nytt stycke musik något vi kommer att ha med oss genom våra hela liv. Att förbereda något nytt kan till tider kännas skrämmande om det har stora utmaningar som vi inte kännas oss bekväma med och gör i några fall att man fastnar i cirkel av frustration som kan vara svår att komma ut ur. Genom mina år som gitarrist har jag ofta känt att vissa musikstycken är för svårAs a musician, the study of a new piece of music is something that we will have with us throughout our whole lives. Preparing something new can at times feel daunting if it has major challenges that we do not feel comfortable with and in some cases make you get stuck in a circle of frustration that can be difficult to get out of. Throughout my years as a guitarist, I have often felt that some pie
I mitt arbete har jag valt att studera kopplingen mellan musik och bildkonst. Min upplevelse är att musik blir förstärkt av konsten och vice versa. Jag har skrivit kompositioner som ska spelas till ljusfilmer av ljuskonstnären Åsa Wirling. Hon kommer projicera filmer på en duk, samt på musikerna. Musik talar starkare till mig genom bild och vad jag valt att studera är förhållandet mellan musik ochIn the preparations for my degree concert, I have chosen to study the connection between music and visual art. In my opinion, music becomes stronger in collaboration with other art genres and vice versa. My original compositions will be performed live, with abstract films made by the light artist, Åsa Wirling, will be projected simultaneously behind and on the band. To me, music speaks stronger th
The positive correlation between elevated expression of wingless-type mammary tumor virus integration site family member 5A (WNT5A) and metastatic potential in melanoma has been extensively explored. However, detailed mechanistic aspects regarding how WNT5A promotes increased melanoma aggressiveness remains unknown. Myristoylated alanine-rich C-kinase substrate (MARCKS), an intracellular protein c
Den här komparativa studien redogör för skillnaderna mellan Sverige och England vid uppsägningsfall som hänför sig till personliga skäl, specifikt misskötsamhet och sjukdom. Syftet är att se hur de båda länderna skiljer sig åt innan och vid uppsägningsfall som hänför sig till personliga skäl. För att göra jämförelsen är studien grundad i en rättsdogmatisk metod. De rättskällor som främst använts äThis thesis discusses the differences in case of dismissal in forms of personal matters such as misconduct and illness in Sweden and England. The purpose is to see how the dismissal takes place before and during the dismissal in the two countries. In order to do this comparative study, the legal dogmatic method have been used. The sources of law that have been used is primarily precedents, the two
During decades men, and especially young adults, have been overrepresented in statistics for traffic accidents. It is known that this trend is linked to men’s riskier behaviour when driving. Sweden has a zero vision (Nollvisionen), which states that no one should die or be seriously injured in traffic and is applied for all road safety work. Therefore, it is of interest to work to prevent risk beh
How to increase trade flows in today's globalized world is a relevant topic and the incentives to do so are exemplified by the WTO Trade Facilitation Agreement that came into force in 2017. Inefficient trade procedures have proven to aggravate and decrease trade. Inefficient trade procedures could be obtaining, preparing and submitting documents about the traded good to authorities, as well as
The marine ecosystem in the Baltic Sea is affected by multiple stress factors, e.g. eutrophication and deoxygenation, overfishing and anthropogenic pollution. Here we evaluate the short-term trends of dissolved oxygen in bottom waters and changes in the primary productivity within a coastal inlet in the Baltic Sea. Undisturbed sediment cores (mean sedimentation rate 0.5 cm yr-1) were retrieved fro
Andelen förnybar kraft växer i produktionsmixen, med löften om att ersätta traditionell fossilintensiv kraftproduktion. I kombination med en trend mot elektrifiering av transporter uppstår nya möjligheter som användning av elfordon för att hantera variabiliteten i förnybar kraftproduktion. Detta examensarbete utforskar potentialen i att använda sådana balanserande tekniker, ofta refererade till soThe share of renewable power grows in the generation mix, wielding promises of substituting traditional CO2-intensive power production. In combination with the trend towards electrification of transport, opportunities are emerging to use electric vehicles for balancing the variability of the renewable power sources. This master thesis explores the potential for such balancing techniques, often ref
The size of the pension payments is a result of how well the pension capital has been invested by the life insurance company. The laws for how much of the pension capital the life insurance companies are able to invest, and how much they need to keep as capital requirement, are under investigation. This is regulated by the risk measure value at risk. Finansinspektionen has released a test report,
