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Jewelry design is a complex and craft-based practice involving diverse activities, processes, and interactions with a range of actors to create jewelry that meets clients’ individual needs. However, how jewelry design, as a practice, is carried out is not very well described and, therefore, is not fully understood. Investigating how designers manage their work, what inspires them, how they relate
Objective: We investigated the risk for alcohol use disorder (AUD) and drug use disorder (DUD) in the offspring of parents with major depression (MDD) or bipolar disorder (BD), including how parent and offspring sex impact familial transmission. Method: Offspring born in Sweden during 1970–1990 in intact families with parental MDD or BD (n = 1,218,920) were examined using Swedish population regist
The upcoming revision of the Energy Performance of Buildings Directive (EPBD) will require reporting of the whole life-cycle global warming potential (GWP) for new buildings from 2028 at the European level. In the Nordic countries, several frontrunners have already introduced national climate declaration requirements for new buildings. The focus was primarily on embodied emissions from building ma
Background: Characterizing the immune landscape of thymic epithelial tumors (TETs) is essential for patient stratification for emerging immunotherapeutic approaches and for optimizing follow-up strategies. In this study, we examined the expression patterns and clinical significance of five immune-related markers in a large cohort of TETs. Material and methods: Expression of TIM3, OX40L, GTF2I, XPO
When the dimensions of structures shrink to the order of the inelastic mean free path of the energy-carrying quasi-particles, the character of energy transport changes from diffusive to ballistic. However, the point of transition remains a matter of debate. Here, we leverage the fluence-dependent transport efficiency to distinguish ballistic and diffusive electron transport in an approach not rely
Social epidemiologists frequently aim to quantify how social, spatial, or organizational contexts shape individual outcomes, an aim commonly addressed through the use of multilevel models. These models readily estimate the magnitude of group-level differences, but it is more difficult to formalize the uncertainty in the relative ordering of predicted group-level outcomes, which is often considered
Intermittent hypoxia (IH), the defining physiological feature of obstructive sleep apnea, has been strongly linked to cardiovascular morbidity, yet the early myocardial effects of short-term IH remain poorly characterized. In this study, we investigated whether brief IH exposure elicits adaptive anti-apoptotic signaling or early injurious activation of intrinsic apoptotic pathways in the murine he
Varför är Sverigedemokraterna intresserade av historia när så få andra politiska partier i vår samtid verkar vara det? Vilken historia är det som lockar och hur görs den till politiska poänger? Svaren finns i deras nationalistiska ideologi. Här ses historien genom ett särskilt prisma där nationalismen avgör hur händelser och personer framträder. Genom att konstruera existensen av en nationell ödes
We demonstrate that the weak gravity conjecture (WGC) and the Festina-Lente conjecture (FLC) yield novel bounds on any hypothetical fifth force and millicharged particles (mCPs), as well as on the scale of inflation and on the effective Higgs quartic interaction. In particular, we find that combining the FLC with inflation leads to stronger bounds on mCPs than what the simple application of the FL
The United Nations and European Union have set ambitious conservation goals to halt and reverse declines in biodiversity by protecting 30% of land and sea areas by 2030. Effective conservation planning requires evidence-based spatial prioritization to maximize the coverage of species within designated protected areas. Based on a pan-European database for occurrence and abundance of breeding birds
Pancreatic islets of Langerhans are central to the pathogenesis of all major forms of diabetes. The ability to study human islets ex vivo has advanced our understanding of diabetes and aided in the development of novel therapeutics. However, for decades, very few laboratories had access to this critical resource and experiments on human islets were typically underpowered. More recently, multiple c
Damselflies (Odonata: Zygoptera) have evolved highly developed visual systems for mate recognition, flight and prey detection. Wing Interference Patterns (WIPs), which are colors generated by thin-film interference in the wing membrane, could function as visual signals and play a role in sexual selection. Because the color of these signals depends on membrane thickness, a potential conflict exists
For more than a decade, stem cells have been on the horizon as a future treatment for Parkinson's disease (PD) and with this vision, it is anticipated that this novel treatment approach may be a paradigm shift in treating PD. The field has progressed enormously during the past few years and several clinical phase I/IIa trials using human embryonic stem cells or induced pluripotent stem cells as so
One characteristic trait of populism is its dramatic rhetoric onthemes such as the survival of the European people. This is particularlypresent in a cluster of conspiracy theories, in this article discussed un-der the collective term le grand remplacement, forming a cornerstoneof much right-wing populist rhetoric. In this article, it is suggested thatthe notion of “apocalyptic imaginaries” is a heOne characteristic trait of populism is its dramatic rhetoric on themes such as the survival of the European people. This is particularly present in a cluster of conspiracy theories, in this article discussed under the collective term le grand remplacement, forming a cornerstone of much right-wing populist rhetoric. In this article, it is suggested that the notion of “apocalyptic imaginaries” is a
We present a method for obtaining an initial-state parton shower model where the (backward) evolution is fully consistent with the (forward) evolution of the collinear parton density is used. As a proof-of-concept we use parton densities obtained with the Parton Branching (PB) approach, and modify the default initial-state shower in PYTHIA8 with this method for consistency. PB is ideally suited fo
This paper examines how transnational conservative religious networks (TCRNs) have cemented their position as major players in the Organization of American States (OAS) in order to dispute reproductive rights and rights relating to sexual diversity. Drawing on fieldwork, interviews and legal analysis in general assemblies and summits of the Americas (2020-2025), it identifies three main strategies
