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Den här rapporten är en del av ett större utvecklingsprojekt och baseras på en serie digitala forskningscirklar för kuratorer inom hälso- och sjukvården som pågick mellan 2020 och 2022. Författarna undersöker, med hjälp av anteckningar från forskningscirklarna och egna erfarenheter som kliniskt verksamma kuratorer, hur deras arbete kan förstås både inom den egna professionen och i samverkan med an

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Delignification is a critical step of the wood fractionation process in a biorefinery. It directly influences the purity of lignin and aids in breaking bonds within lignin and lignin–carbohydrate complexes surrounding cellulose. The recalcitrant nature of lignocellulose poses challenges in fractionating the material, notably during delignification. Recent progress in understanding lignin’s ph

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In North and East Syria—also known as Rojava—the convergence of war, politics, and environmental challenges presents a complex and pressing reality. This blog is dedicated to exploring these interlinked issues, highlighting how conflict and ecological degradation are deeply connected, and how these dynamics affect communities in varied and unequal ways.

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Årligen upptäcks nya kärlväxter i Sverige. Det kan vara arter som etablerar sig i Sverige i klimatförändringarnas spår, som följer med internationella transporter, och inte minst trädgårdsrymlingar. Det finns flera skäl till att dokumentera dessa, inte minst för att förebygga spridning av invasiva arter. Biologiska museet i Lund tar emot belägg och listar här de arter som var nya för Sverige 2023.

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Aim: To study academic, social and psychiatric outcomes among adults in the general population in southwestern Sweden. Groups of individuals born in 1998 and ineligible, eligible but not completed, and eligible and completed upper secondary school were followed in 2020. Methods: Data were retrieved from Statistics Sweden, the Swedish National Agency for Education, the Longitudinal Integrated Datab

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Bacterial reverse transcriptases (RTs) are a large and diverse enzyme family. AbiA, AbiK and Abi-P2 are abortive infection system (Abi) RTs that mediate defense against bacteriophages. What sets Abi RTs apart from other RT enzymes is their ability to synthesize long DNA products of random sequences in a template- and primer-independent manner. Structures of AbiK and Abi-P2 representatives have rec

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The royal warship Vasa sank on her maiden voyage in 1628. She was discovered in 1956 and in 1961, after 333 years at the bottom of the sea in the Stockholm harbour she was salvaged. Vasa, built mainly of oak, was one of the first major objects to be conserved with polyethylene glycol. She was sprayed continuously for 17 years followed by an 11 year long controlled drying procedure HBfors,[l]). In

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OBJECTIVE: Radical cystectomy (RC) for bladder cancer is associated with an inherent risk of complications and even postoperative mortality. The number of hospitals performing RC has decreased in Sweden over time, and since a formal regional centralization in 2017 cystectomy care is currently provided by nine hospitals. MATERIAL AND METHODS: In the Swedish National Urinary Bladder Cancer Register

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The study of microbial diversity over time and space is fundamental to the understanding of their ecology and evolution. The underlying processes driving these patterns are not fully resolved but can be studied using population genetic approaches. Here we investigated the population genetic structure of Gonyostomum semen, a bloom-forming phytoplankton species, across two continents. The species ap

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The genome of cancer cells is unstable. Flaws in the DNA repair mechanisms of these cells can lead to the creation of gene fusions, where parts of two different genes are erroneously combined. Additionally, the expression of microRNAs (miRNAs), small regulatory molecules that control gene activity, is often dysregulated in cancer. In this thesis, we investigate miRNAs, gene fusions, and the interp

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The sometimes rapid development of (new) threats and extraordinary events calls for a robust, flexible, and well-equipped civil crisis preparedness system to respond and limit the damage of crisis events. To achieve this, Swedish municipalities and regions are required by law to regularly perform and report risk and vulnerability analysis ‘bottom up’ to governmental agencies. When performed in lar

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Background: Heart failure with reduced ejection fraction (HFrEF) is characterized by ventricular remodeling and impaired myocardial energetics. Left ventricular pressure-volume (PV) loop analysis can be performed noninvasively using cardiovascular magnetic resonance (CMR) imaging to assess cardiac thermodynamic efficiency. Objectives: The aim of the study was to investigate whether noninvasive PV

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Metabolic rewiring is a key feature of cancer cells to support the demands of growth and proliferation. The metabolism of amino acids is altered in many cancers, including pancreatic cancer. The cellular uptake of amino acids is regulated by amino acid transporters, such as L-type amino acid transporter 1 (LAT1). Accumulating evidence suggests that LAT1 is overexpressed in pancreatic cancer and co

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Solid-liquid interfaces are at the heart of a wide variety of phenomena. Their investigation requires experimental techniques with surface sensitivity such scanning probe microscopy and nonlinear optical techniques. In recent years, solid-liquid interfaces have been investigated with a novel approach based on the generation of high frequency acoustic and optical phonons. Due to the sensitivity of