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Apolipoprotein M (apoM) is a member of the lipocalin superfamily and is predominantly associated with high-density lipoprotein (HDL). It was found that apoM is the chaperon to the bioactive sphingolipid, sphingosine-1-phosphate (S1P). Several studies have since contributed to expand the knowledge on apoM, S1P, and the apoM/S1P-complex in cardiovascular diseases. For instance, the HDL-bound apoM/S1

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Key stakeholders from the cancer research continuum met in May 2021 at the European Cancer Research Summit in Porto to discuss priorities and specific action points required for the successful implementation of the European Cancer Mission and Europe's Beating Cancer Plan (EBCP). Speakers presented a unified view about the need to establish high-quality, networked infrastructures to decrease cancer

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Quantum computing technology will greatly enhance the abilities of the emerging field of computational law to express, model, and operationalise law in algorithmic form. Foreshadowing the harnessing of the power of quantum computing technology by the legal sector, this essay targets, with reference to computational complexity theory, the categories of computational problems which quantum computers

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A turbine blade tip with a trapezoidal slot cooling scheme is first proposed in the current paper. The film cooling characteristics of a turbine blade tip with a trapezoidal slot scheme are experimentally studied by the pressure sensitive paint (PSP) technique in transonic flow. Varieties of density ratio, tip clearance gap and position of the trapezoidal slot scheme are selected as investigation

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Påståendet att kommunikatörerna på våra lärosäten vill dölja information för allmänheten är ett allvarligt och felaktigt påstående. Det skriver professorerna Jesper Falkheimer och Mats Heide i en replik.

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Exclusive dimuon production in ultraperipheral collisions (UPC), resulting from photon-photon interactions in the strong electromagnetic fields of colliding high-energy lead nuclei, PbPb(γγ) → μ+μ-(Pb(∗)Pb(∗)), is studied using Lint = 0.48 nb-1 of √sNN = 5.02 TeV lead-lead collision data at the LHC with the ATLAS detector. Dimuon pairs are measured in the fiducial region pT,μ > 4 GeV, |ημ| <2.4, i

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A search for pair production of bottom squarks in events with hadronically decaying τ-leptons, b-tagged jets, and large missing transverse momentum is presented. The analyzed dataset is based on proton-proton collisions at √s=13  TeV delivered by the Large Hadron Collider and recorded by the ATLAS detector from 2015 to 2018, and corresponds to an integrated luminosity of 139  fb−1. The observed da

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Non-ionizing energy loss causes bulk damage to the silicon sensors of the ATLAS pixel and strip detectors. This damage has important implications for data-taking operations, charged-particle track reconstruction, detector simulations, and physics analysis. This paper presents simulations and measurements of the leakage current in the ATLAS pixel detector and semiconductor tracker as a function of

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Aims: Peripheral artery disease (PAD) constitute a high-risk with adverse clinical outcomes. We aimed to investigate the cardiovascular outcomes following myocardial infarction (MI). Methods and results: This nationwide, Danish register-based follow-up study includes all patients experiencing an MI between 2000 and 2017. Patients with and without PAD were compared. Multivariable logistic regressio

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Studies on Security Force Assistance (SFA) have hitherto been dominated by different iterations of the principal-agent perspective to explain relations between provider and recipient. Yet, while such frameworks aptly illustrate these dynamics from a macro perspective, they are inadequate when analysing the complexity of practices on the ground. To mitigate this short-coming, the present article us

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Correlations of two flow harmonics vn and vm via three- and four-particle cumulants are measured in 13 TeV pp, 5.02 TeV p+Pb, and 2.76 TeV peripheral Pb+Pb collisions with the ATLAS detector at the LHC. The goal is to understand the multi-particle nature of the long-range collective phenomenon in these collision systems. The large non-flow background from dijet production present in the standard c

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We present mass models of the Milky Way created to fit observational constraints and to be consistent with expectations from theoretical modelling. The method used to create these models is that demonstrated in our previous study, and we improve on those models by adding gas discs to the potential, considering the effects of allowing the inner slope of the halo density profile to vary, and includi

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Objective: ACTH is considered a weak marker for autonomous cortisol secretion (ACS) in patients with adrenal incidentalomas (AIs). Our aim was to investigate suppressed basal ACTH as a marker of ACS and to elucidate why this criterion is of limited value. Methods: Basal ACTH and cortisol after overnight dexamethasone suppression test (cortisolONDST) were measured in 198 patients with unilateral AI

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Nasopharyngeal cancer (NPC) is associated with Epstein-Barr virus (EBV) and EBV antigen may be utilized for therapeutic purposes, including targeting of dendritic cells (DCs). Although DCs may be present in NPC, the information is limited and not up-to-date with current knowledge on DC subsets. In the present study, biopsies from untreated NPC were obtained and subjected to multicolor flow-cytomet

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© 2019 Spandidos Publications. All rights reserved. Apolipoprotein M (ApoM) is a type of apolipoprotein. It is well known that high-density lipoprotein (HDL) decreases inflammatory responses via the apoM-sphingosine-1-phosphate (S1P) pathway. The present study further investigated the importance of ApoM in the inhibitory effects of HDL on inflammation. Mice with an apoM gene deficiency (apoM-/-) w

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This paper communicates the results of a reassessment of the original burial position of the Barum burial, Scania, Sweden, dated to c. 8,700 years ago. Based on a thorough analysis of the photographs from Folke Hansen’s excavation, it is concluded that the body was placed in an upright sitting position. The notion that the body was leaning backwards is based on a faulty interpretation of the origi

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Hur struktureras det konkreta och vardagliga arbetet med dokumenteringen? Hur interagerar vård- personalen med dokumenten och med varandra i anslutning till dokumente- ringen? Hur pratar vårdpersonalen om dokumenteringspraktikerna? Vilken mening och funktion tillskrivs dokumenteringen?En utmaning är att trots den uttalade administrationskritiken kunna urskilja nödvändig och meningsfull dokumenteri