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Paediatric prospective studies of coeliac disease with longitudinal collection of biological samples and clinical data offer a unique perspective on disease risk. This Review highlights the information now available from international paediatric prospective studies on genetic and environmental risk factors for coeliac disease. In addition, recent omics studies have made it possible to study comple

Introduction: Single Bicycle Brashes (SBCs) are common, and underreported in official statistics. In urban environments, light rail tram tracks are a frequent factor, however, they have not yet been the subject of engineering analysis. Method: This study employs video-based analysis at nine Dublin city centre locations and introduces a predictive model for crossing success on tram tracks, utilisin

Purpose: An increasing number of children and young adults with complex medical conditions and respiratory failure are treated with home mechanical ventilation (HMV). The current study aimed to describe how young adults using HMV experience their everyday life with the ventilator, their physical impairments and their opportunities for an educational and professional career. Materials and methods:

How can ludic play frame and assist the participants' interactions in an immersive opera? The Consultant's Quest was developed as an artistic response to the idea and the challenge of integrating articulated game-playing as a both methodic and affective instrument in relation to operatic elements. Presented as a card-driven board game in connection to the operatic experience The Prophecies, The CoHow can ludic play frame and assist the participants' interactions in an immersive opera? The Consultant's Quest was developed as an artistic response to the idea and the challenge of integrating articulated game-playing as a both methodic and affective instrument in relation to operatic elements. Presented as a card-driven board game in connection to the operatic experience The Prophecies, The Co

In this paper, a high-isolation two-port co-linearly polarized (co-LP) composite antenna is proposed. Dipole and W8JK array modes with co-LP omnidirectional patterns can be simultaneously supported by a plate with two etched back-to-back tapered slots. A microstrip differential and a T-divider coupling feeding networks are developed to selectively excite the dipole and W8JK modes, which results in

Mary Wollstonecraft (1759–1797) was an English philosopher in the Enlightenment tradition, writer, novelist, and book reviewer. She was an advocate for women’s rights and for equality of wealth and privilege and supported the French Revolution. She made her name in 1790 as the author of A Vindication of the Rights of Men, the first published commentary on Edmund Burke’s critique of the French Revo

The Prophecies is an AI-based chamber opera with interactive features in which the visitors are immersed in a ritualistic and temple-like setting where they can meet a singing oracle who instead of appearing to be connected to ancient divinities receives messages from the digital realm. The underlying theme of the opera is the eternal human search for guidance and our hope for help from external a

Introduction: The ability of species to colonize newly suitable habitats under rapid climate change can be constrained by migration processes, resulting in a shift of the leading edge lagging behind the ameliorating climate, i.e. migration lag. The importance and extent of such migration lags during the forest expansion after the Last Glacial Maximum (LGM) are still debated. Similarly, the relativ

Excited state evolution of the rhodium(iii) complex [Rh(iii)(phen)2(NH3)2]2+ (phen = 1,10-phenanthroline) has been investigated theoretically to gain a better understanding of light-driven activation of high-energy metal centered states. Ab initio molecular dynamics (AIMD) simulations show the significance of asymmetric motion on a multidimensional potential energy landscape around the metal cente

This paper explores the relationship between the Vertical Sky Component (VSC) metric and the European and Swedish daylighting regulations. VSC, a static geometrical metric, is considered a useful early indicator of indoor daylighting, as it is insensitive to late-stage design details such as material properties and internal layout. However, its relationship with modern building daylighting legisla

In addition to the major nutrients carbon, nitrogen, and phosphorus, many minor elements play an important role in the function of freshwater systems. Such elements may function as essential micronutrients, or they may affect the biota by being toxic, or they play an indirect role by influencing the mobility and availability of other elements. This chapter covers the fundamentals of important mino

Ternary oil-water-surfactant systems can give rise to an O/W microemulsion in equilibrium with excess oil, a W/O microemulsion in equilibrium with excess water, or a bicontinuous microemulsion in equilibrium with excess oil and water. This type of phase behavior has been known for a long time and the three systems are often referred to as Winsor I, Winsor II and Winsor III, respectively after the

Following the idea originally proposed during the ESO-Workshop The Very Large Telescope in 2030, the concept of a high resolution spectrograph for the VLT has been further explored, both for the science and technological aspects. Such an instrument will fill a gap in capabilities amongst the landscape of future instrumentation planned for the next decade. Its key characteristic will be high spectr

Diamond-Blackfan anemia (DBA) is a rare congenital bone marrow failure disorder characterized by erythroid hypoplasia. It primarily affects infants and is often caused by heterozygous allelic variations in ribosomal protein (RP) genes. Recent studies also indicated that non-RP genes like GATA1, TSR2, are associated with DBA. P53 activation, translational dysfunction, inflammation, imbalanced globi

How can the unseen be heard and imagined through operatic means? In the chamber opera In the Darkness, Everything Went All Black – set in pitch-black darkness – the stage was radically inverted. For the purpose of exploring the immersive potential of spatial reversal, methods for operatic creation and presentation were rethought in terms of visibility, layout, work order, and surveillance. Firstly