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Objective: Knee osteoarthritis (OA) is a chronic joint disease associated with pain and reduced function. The mechanisms underlying OA and how mechanical properties change with the disease are not fully understood, partly due to large variability during mechanical testing of cartilage. We characterized the mechanical properties of human femoral cartilage with varying levels of degeneration using a

Histologically stained tissue sections are considered the gold standard for studying microscopic anatomy and diagnosing disease in clinical practice. However, the processes of sectioning and staining are laborious, and the overall method relies on two-dimensional analysis. In contrast, X-ray-based virtual histology offers the advantage of virtual sectioning while retaining the full three-dimension

The Nature-Based Solutions (NbS) framework offers a promising pathway to address societal challenges such as food security, water management, and biodiversity loss, all under accelerating climate change. Aquatic ecosystems are central to addressing these challenges; however, their current implementation remains largely focused on isolated sites, limiting their effectiveness at landscape scales. He

BACKGROUND: Childhood cancer survivors (CCS) are reported to have decreased bone mineral density (BMD).PURPOSE: Is premature ovarian insufficiency (POI) an important risk factor for low BMD in CCS at long term follow-up?PATIENTS AND METHODS: Altogether 167 female CCS, median age 34 (19-57) years, treated for childhood cancer under age 18 years between 1964 and 2008, with a follow-up time of 25 (12

Amid overlapping global crises, many individuals experience psychological distress, anxiety, hopelessness, and a diminished sense of agency. Scholars increasingly argue that this erosion of perceived significance may be as consequential as climate change, biodiversity loss, polarization, and political turmoil, as it stems from a growing disconnection or alienation from self, others, and nature at

Äldreomsorgen har betydande utmaningar kopplade till demografiska förändringar, ökade vårdbehov och svårigheter att rekrytera och behålla personal. Trots detta vet vi relativt lite om hur arbetsmotivationen ser ut och hur olika motivationsmönster hänger samman med viljan att stanna kvar i yrket.Med utgångspunkt i Självbestämmandeteorin syftade studien till att identifiera och karaktärisera olika m

I denna rapport analyseras jordbrukssektorns potential att bidra med biomassa till biobaserade produkter och energi. Som jämförelse beskrivs också skogssektorns potential översiktligt. Syftet är att skapa en kunskapsbas för vidare studier om tillgången på biomassa, konkurrens mellan användningsområden, framtida biomassapotentialen för biogasproduktion samt behovet av styrmedel i omställningen mot

OBJECTIVE: Bacteria present on extracted bone flaps during decompressive craniectomy inhibit bone flap reimplantation. An adapted treatment with antibiotic mixture for decontamination of allografts could be used in neurosurgery for preparation of bone flaps for autologous cranioplasty.METHODS: Eleven bone flaps were analysed using standardised bacterial cultures and droplet digital Polymerase Chai

Background: Dietary management of phenylketonuria (PKU) focuses on restricting phenylalanine (Phe) intake. The European PKU guidelines and the PKU Dietary Handbook recommend a simplified PKU diet, allowing unrestricted consumption of many low-Phe foods, called free foods. While this approach may reduce the treatment burden for patients, its implementation varies. This study investigated practi

A model was developed to calculate shoreline retreat due to sea level rise applicable for coastal areas with complex topography, varying wave and sediment conditions, and limited material supply. As a test case, the model was employed to the south Swedish coast to demonstrate the possibility to investigate large geographical areas using readily available input data. Equilibrium profiles of differe

Background: Evidence-based radiography (EBR) is one of the cornerstones of modern Radiography. The integration of EBR into clinical practice remains challenging, and radiology nurses (RNs) often face barriers due to time constraints, production demands, and limited research tradition within their professions. Objective: The objective was to explore how experienced RNs conceptualize EBR before, dur

The aim of this study is to investigate what women do in disaster situations and how both men and women perceive and discuss the work of women. These patterns were evidenced in the stories that were told following the largest forest fire in the modern history of Sweden in July 2014. The study is based on 31 retrospective interviews with volunteers involved in combating the forest fire and concentr

In 2025 Huminfra, Sweden’s national infrastructure for digital and experimental humanities, entered its second funding period, the consolidation phase, and successfully met all first-year targets.First, the Huminfra website, https://www.huminfra.se/, was further developed and maintained. This is the central gateway to Swedish digital and experimental research resources which collates and links to