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BACKGROUND: Primary headache disorders such as migraine and cluster headache exhibit circadian and circannual variations in attack onset. Melatonin plays a central role in regulating biological rhythms and likely influences the timing of headache attacks. Recent evidence suggests melatonin may be a promising treatment for migraine and cluster headache; however, underlying mechanisms need to be elu
INTRODUCTION: The COVID-19 pandemic significantly disrupted melanoma care worldwide, raising concerns about diagnosis and treatment delays.OBJECTIVES: To compare changes in incidence and prognostic factors of invasive cutaneous melanomas across two regions with contrasting COVID-19 infection control strategies.METHODS: A retrospective population-based registry study using the Swedish quality regis
Background Preclinical and clinical data following acute myocardial infarction (MI) have shown conflicting results whether a bimodal pattern of edematous myocardium at risk (MaR) on cardiovascular magnetic resonance (CMR) imaging during the first week exists or not. The objective was to assess the dynamics of MaR following acute experimental MI using a comprehensive CMR protocol. Methods Acute MI
Background: Emergency departments use triage to identify time-critical patients and reduce waiting times by assigning higher priority. However, no existing method directly measures this core clinical function. We developed and validated Triage Effectiveness (TE) as a framework for quantifying how well triage systems reduce waiting times for time-critical patients. Methods: Using data from 463,209
Bats are the only mammals capable of powered flight, allowing them to cover relatively long distances in a short time. However, the general inability of mammals to fuel endurance exercise solely by oxidizing fatty acids may prevent bats from undertaking long-distance intercontinental migrations—like birds do. Here, we conducted untargeted metabolomics to reveal the oxidative fuels used by wild cau
Lateral subsurface flow (LSF) is a key component of rainfall-runoff generation on alpine forested slopes, but the influence of weathered bedrock on LSF remains poorly understood due to methodological constraints in monitoring three-dimensional flow dynamics. This study addresses this gap by proposing a standardized morphological interpretation framework for time-lapse 3D electrical resistivity tom
Achieving isoform selectivity within the galectin family remains a central challenge in glycomimetic drug design due to the highly conserved architecture of their carbohydrate recognition domains. Here, we define the structural and thermodynamic basis of recognition of a series of C-glycosylic 1,2-thiodisaccharides targeting human galectin-7 and the N-terminal domain of galectin-8 (galectin-8N). U
Aim: We aimed to investigate the prevalence of self-reported kinesiophobia seven months after out-of-hospital cardiac arrest (OHCA) and its relationship with self-reported and objectively assessed physical activity. Additionally, to explore the relationship between self-reported kinesiophobia and symptoms of anxiety and depression.Method: Cross-sectional sub-study conducted within the Targeted HypAim: We aimed to investigate the prevalence of self-reported kinesiophobia seven months after out-of-hospital cardiac arrest (OHCA) and its relationship with self-reported and objectively assessed physical activity. Additionally, to explore the relationship between self-reported kinesiophobia and symptoms of anxiety and depression.Method: Cross-sectional sub-study conducted within the Targeted Hyp
The internal structures of the semi-magic, neutron-rich N=126 nuclei, 203Ir and 202Os, were studied. The nuclei of interest were produced using relativistic-energy projectile fragmentation of a 208Pb beam at the GSI facility in Germany. Internal isomeric decays were investigated via delayed γ-ray spectroscopy. In 203Ir, four observed transitions were associated with parallel decay branches from an
Modular multiplication (MM) is the main operation in cryptography algorithms such as elliptic-curve cryptography (ECC) and Rivest–Shamir–Adleman, where repeated MM is used to perform elliptic curve point multiplication and modular exponentiation, respectively. The algorithm for the proposed architecture is derived from the Chinese remainder theorem and performs MM completely within a residue numbe
Systolic arrays (SAs) for matrix multiplication are commonly used in machine learning (ML), wireless communication, and signal processing. Inherently offering high throughput with good data reuse, they are well-positioned for both low-power edge devices and accelerator applications in high-performance computing. Current realizations suffer from startup latency, defined as the time required to full
The modern information landscape is complex and often chaotic, making it difficult for individuals to discern what constitutes credible evidence. Addressing this gap, we explore how systems and processual perspectives show how evidence should not primarily be seen as a static “thing" or fact but rather as a relational property and a dynamic activity. This perspective informs us that our view of th
The object of study of this thesis is Fierté nationale: De Jéricho vers Gaza, a film that I shot in 2019 and completed in 2025, which follows Hassan Al Balawi—a Palestinian diplomat to Europe—as he returns to Palestine on the occasion of the fifteenth anniversary of the death of Yasser Arafat, former leader of the Palestine Liberation Organisation (PLO). Rather than beginning with a predefined res
PurposeDemocracy is often invoked as a core value of public libraries, archives and museums (LAMs) in Western countries. This article starts from the proposition that democratic work in LAMs is more than a mission statement, an abstract ideal, or a rhetorical label. Therefore, it presents the Flower Monster workshop, a creative visual workshop tool designed to help LAM professionals critically exaPurposeDemocracy is often invoked as a core value of public libraries, archives and museums (LAMs) in Western countries. This article starts from the proposition that democratic work in LAMs is more than a mission statement, an abstract ideal, or a rhetorical label. Therefore, it presents the Flower Monster workshop, a creative visual workshop tool designed to help LAM professionals critically exa
Barn har rätt till umgänge med båda föräldrarna, även om de inte lever tillsammans. Det slås fast i både svensk och brittisk lagstiftning, men länderna har valt olika förhållningssätt till hur faderskapet ska utformas efter en separation. Vilket av dessa system främjar barnets bästa?
Over the years, public service has entered a transition into collaboration as a means of accomplishing common goals for the good of society. Collaborative work across professions has long played an essential role in providing integrated services in response to complex societal problems. Inter-professional collaboration involves integrating different skills and competencies, which is described as a
