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Background: Current guidelines recommend androgen deprivation therapy only for men with very high-risk prostate cancer (PCa), but there is little evidence to support this stance. Objective: To investigate the association between radical local treatment and mortality in men with very high-risk PCa. Design, setting, and participants: Semiecologic study of men aged <80 yr within the Prostate Cancer d

Popular Abstract in Swedish Epidemiologi är den vetenskap som studerar sjukdomars förekomst och spridning och hur detta varierar över tiden, mellan geografiska områden och mellan grupper av individer definierade i olika termer. I Malmö finns det mycket goda möjligheter att göra epidemiologiska studier av slaganfall (stroke). Dels finns ett register som följt strokeinsjuknandet sedan 1989. Dels har

Popular Abstract in Swedish Med föreliggande avhandling vill jag belysa att Chrétien de Troyes Graalsaga, till skilnad från vad de åtskilliga kritiker har påstått, inte bygger på traditionella ridderliga värden, men väl avslöjar en problematisk ideologi. Denna ideologi prövas med hjälp av V. Jouves metod, som beskrivs i hans Poétique des valeurs. Graalsagans värden analyseras ur ett dubbelt perspThis dissertation aims at showing that Chrétien de Troyes' Conte du Graal does not, as often affirmed, uphold traditional chivalrous values, but discloses a problematic ideology, mostly as a result of multiple interactions at the textual level. In order to examine ideology, Le Conte du Graal is analysed in the light of the poetics elaborated by Vincent Jouve in his Poétique des valeurs (2001). Fol

The purpose of this work is to investigate the interaction between transport processes and chemical reactions, with special emphasis on modeling mass transport by the Lattice Boltzmann method (LBM) at microscale of the anode of a solid oxide fuel cell (SOFC). In order to improve the performance of an SOFC, it is important to determine the microstructural effect embedded within the physical and che

Popular Abstract in Swedish Bakgrund I Sverige erbjuds samtliga gravida kvinnor ett rutinultraljud vid 18-20 graviditetsveckor. Syftet med undersökningen är att fastställa antalet foster, uppskatta graviditetslängd samt granska fosteranatomin för att upptäcka eventuella missbildningar. En del missbildningar kan man se med ultraljud, men långtifrån alla. Att redan under graviditeten känna till om The aim was to evaluate first trimester nuchal translucency (NT) measurement for detection and risk assessment of fetal malformations and fetal loss. 39 572 pregnant women were randomised to either a routine ultrasound scan at 12-14 weeks including NT measurement or to a routine scan at 18-20 weeks. Prenatal diagnosis of major congenital heart malformations was compared between the two groups. In

Preclinical studies on the role of erythropoietin (EPO) in bone metabolism are contradictory. Regeneration models indicate an anabolic effect on bone healing, whereas models on physiologic bone remodeling indicate a catabolic effect on bone mass. No human studies on EPO and fracture risk are available. It is known that fibroblast growth factor 23 (FGF23) affects bone mineralization and that serum

Cycling provides numerous benefits to individuals and to society but the burden of road traffic injuries and fatalities is disproportionately sustained by cyclists. Without awareness of the contributory factors of cyclist death and injury, the capability to implement context-specific and appropriate measures is severely limited. In this paper, we investigated the effects of the characteristics rel