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A systematic assessment of radiotherapy for cancer was conducted by The Swedish Council on Technology Assessment in Health Care (SBU) in 2001. The assessment included a review of future developments in radiotherapy and an estimate of the potential benefits of improved radiotherapy in Sweden. The conclusions reached from this review can be summarized as: Successively better knowledge is available o
Popular Abstract in English We won’t give up Anatolia! Shouting this slogan, thousands of villagers marched towards Ankara, protesting against the projects that threaten to channel Anatolian rivers into hydro-power plants. The majority of demonstrators did not reach Ankara. The police stopped them at the city gates for disturbing the public order: hydroelectricity development is a national prioritPrivate Rivers is a study of contested processes whereby use rights to water are privatised for electricity production. It engages with the issues of renewable energy solutions and the sustainability of run-of-river hydro projects in Turkey by investigating the connection between these policies and justice for rural populations, whose livelihood depends on the rivers. Since 2001, water privatisati
Background Several pressing issues face municipal planners including increased land use and climate change. Managing these issues requires a balance between different actions to accommodate citizen’s demands of ecosystem services (ES) and development projects. The implementation of ES as a new tool for assessments needs to be contrasted by research considering existing tools such as Environmental
Singular perturbations of Schrödinger type operators are of interest in mathematics, e.g. to study spectral phenomena, and in applications of mathematics in various sciences, e.g. in physics, chemistry, biology, and in technology. They also often lead to models in quantum theory which are solvable in the sense that the spectral characteristics (eigenvalues, eigenfunctions, and scattering matrix) c
The major histocompatibility class I (MHC-I) genes are highly polymorphic and the proteins that they encode play a crucial role in both the innate and the adaptive immune response. A MHC-I molecule consists of three parts, one polymorphic heavy chain, one invariant light chain, β2-microglobulin and a peptide of usually between 8-11 amino acids in length. The maturation and quality control of MHC-I
Abstract COPD is a major cause of chronic morbidity and mortality throughout the world. It is a preventable and treatable disease. Smoking is the most commonly encountered risk factor for COPD and the habit now unfortunately starts at earlier ages than before. There is a strong necessity to diagnose COPD in early stages before symptoms present themselves. MRI with hyperpolarized 3He using diffusio
In the US and most European countries, testicular cancer is the most common malignancy in young men aged 20-40 years. Since the introduction of cisplatin-based treatment in the 1970s, more than 95% of the patients are cured. The increasing incidence of testicular cancer and high survival rates, has led to a growing number of testicular cancer survivors (TCSs). As they have a long life expectancy i
Popular Abstract in Swedish Framtida klimatförändringar påverkas till stor del på människans utsläpp av CO2, samt av klimat- och CO2-relaterade återkopplingar genom kolcykeln i både landbaserade ekosystem och hav. Landbaserade ekosystem tar för tillfället upp omkring 25% av de antropogena utsläppen av CO2 från förbränning av fossila bränslen och markanvändning, men att tillskriva vilka mekanismer The nature of future climate change will depend on anthropogenic emissions of CO2, as well as climate- and CO2-mediated feedbacks through carbon (C) cycling in both terrestrial ecosystems and oceans. Terrestrial ecosystems remove presently about 25% of the anthropogenic CO2 fossil-fuel and land-use change emissions, but to attribute which mechanisms cause this uptake, and the key regions where it
Northern Europe was capped by ice during Weichsel (Wurm), the maximum of which occurred approximately 18,000 years before present. When in the latter part of the 19(th) century the view of an all-devastating land ice (the tabula rasa hypothesis) was generally adopted by natural scientists, plant biogeographers used a simple model predicting a post-glacial, northwards re-migration of species in con
Popular Abstract in Swedish Något tillspetsat förefaller varje kommun driva utvecklingsarbete inriktat på verksamhetsmått. Är så inte fallet är ansvariga snabba att betona att verksamhetsmått är viktigt och att de precis har beslutat om ett större måttprojekt. Denna bok ger en bild av i vilken omfattning fyra gatukontor utformar och använder verksamhetsmått. Boken innehåller också beskrivningar ocThe purpose of this study is to develop a frame of reference within which formal control system performance measures can be described and their design and use can be analyzed for control systems in municipalities. From a cybernetic control approach measures are used as instruments to plan and gain feedback from employee actions, and adjust them to the internal and external environment of which the
Popular Abstract in Swedish Märkesorientering är ett nytt förhållningssätt till varumärken. Inom företag som Nestlé, Pharmacia & Upjohn Nicorette och Volvo utgör varumärkena det nav kring vilket strategierna kretsar. Varumärkesfrågor behandlas inte längre som taktiska spörsmål utan är ledningsfrågor. Målsättningen inom märkesorienterade företag är ytterst att skapa, utveckla och skydda varumärThe aim of this study was to examine how an organisation’s approach to brands can, in the building up of a brand competence, prevent trademark degeneration and develop and protect brands as strategic resources. A line of argument is put forward for adopting a new corporate approach (mind-set) to brands. The starting-point is the concept of trademark degeneration (genericness), which is both the ke
Popular Abstract in English Huntingtons sjukdom (HS), även kallad danssjukan, är en ärftlig och dödlig sjukdom som leder till ofrivilliga motoriska rörelser. Personer med HS får vanligtvis symtom i medelål- dern och avlider efter 15–20 år. Diagnosen ställs klinisk när de första ofrivilliga rörelserna uppträder. Dessa symtom kan kopplas till celldöd i de delar av hjärna som styr vår rörelse. SjukdoHuntington’s disease (HD) is a neurodegenerative disorder caused by an expansion of the CAG repeat in the huntingtin gene. Non-motor symptoms and signs such as psychiatric disturbances and metabolic dysfunction are also part of the disease manifestation. These symptoms often precede the motor symptoms by decades. The hypothalamus is an area in the brain involved in the regulation of emotions and m
Popular Abstract in Swedish Denna avhandling presenterar data från två olika geografiska områden, Dronning Maud land, Antarktis, och den Skandinaviska fjällkedjan som befinner sig på den Baltiska kontinentalplattan. Dessutom presenteras en jämförande studie mellan två metoder att datera bergarter. Berggrunden i Dronning Maud Land domineras dels av migmatiserade bergarter, dels av post-tektoniska This thesis presents data from two areas, Dronning Maud Land, Antarctica, and the Scandinavian Caledonides, Baltica. In addition, a comparative geochronological study is presented. The bedrock of Dronning Maud Land (DML) is dominated by migmatitic gneisses and post-tectonic intrusions. A migmatitic gneiss at Jutulsessen nunataks, Gjelsvikfjella, has a protolith age of 1163 ± 6 Ma and a migmatisati
The main purpose of the present work is to increase knowledge of in-plane tension behav-iour of masonry and develop a model able to describe the impact of parameters influencing cracking caused by restrained shrinkage. In the process the mechanism of load transfer between units and mortar joints is described. The influence of cohesion between units and mortar joints, unit and joint geometry and ex
Popular Abstract in Swedish Njurfunktion inom hjärtkirurgi Akut njursvikt (AKI) efter hjärtkirurgi är en allvarlig komplikation som förekommer i 25-35 % av alla patientfall. AKI medför förhöjd risk för allvarliga komplikationer och död efter hjärtkirurgi. Ett stort fokus ligger på detektion, prevention och behandling av AKI och forskningsfältet uppdateras kontinuerligt. En rad olika läkemedel har Abstract Acute kidney injury (AKI) is a common and serious complication after cardiothoracic surgery and is associated with increased short- and long-term mortality risk. Despite extensive studies in the field, a comprehensive understanding of this syndrome has remained elusive, partly due to divergent definitions of AKI and partly due to the limitations of available routine biomarkers to predict,
