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The introduction of total prostate-specific antigen (tPSA) testing in serum has revolutionized the detection and management of men with prostate cancer. This review will highlight some of the exciting new developments in the field of prostate cancer screening in general and from our SPORE research program at Memorial-Sloan Kettering Cancer Center. First, it is important to understand that the inhe

The global temperature rise is proportional to the cumulative amount of CO2 emissions to the atmosphere. This observation is consistent between climate models and historical observations. It has also given rise to the concept of a carbon budget, which sets a threshold for the amount of CO2 that can be emitted into the atmosphere while still fulfilling political goals such as the Paris Agreement.Te

This publication describes a concept that intends to enable an optimization of machining with regard to the balance between criteria related to technology, economy and sustainability. The work is of a discussion nature and intends to provide a framework for further research and development in the area. Previous research and development during the 80's and 90's is presented in general terms and in

Background: Voluntary self-exclusion from gambling is a common but underdeveloped harm reduction tool in the management of gambling problems or gambling disorders. Large-scale, multi-operator, and operator-independent self-exclusion services are needed. A recent nationwide multi-operator self-exclusion service in Sweden (Spelpaus), involving both land- and web-based gambling sites, is promising, b

Immune thrombocytopenia (ITP) is an autoimmune bleeding disease caused by immune-mediated platelet destruction and decreased platelet production. ITP is characterized by an isolated thrombocytopenia (<100 × 109/L) and increased risk of bleeding. The disease has a complex pathophysiology wherein immune tolerance breakdown leads to platelet and megakaryocyte destruction. Therapeutics such as cortico

The enormous production and consumption of fossil-based plastics has caused severe environmental challenges such as pollution of the ocean, increased CO2-emissions, and various health problems. Many ofthese concerns are intimately connected to the use of fossil fuels in the production of polymers. For this reason, there is a considerable interest to develop bio-based monomers to mitigate some of t

Ces dernières années en Ouganda, les écologistes ont fait l'objet de répressions partout dans le pays. Pour sauvegarder la nature, des journalistes, des étudiants, ainsi que des agriculteurs et des habitants de zones rurales, protestent et se mobilisent contre les injustices et les déplacements forcés causés aussi bien par les infrastructures utilisant des énergies fossiles que par l’agro-industri

Plastics are widely used in our daily lives and industry. Unfortunaltely, most plastics are produced from non-renewable fossil resources. The transition toward sustainable resources such as various biomass is critically important for the future of plastic industry and the whole society. Polyesters consitute a major class of plastics, which are widely used in textiles, packaging and other applicati

Advances in understanding how cancer cells interact with the immune system allowed the development of immunotherapeutic strategies, harnessing patients’ immune system to fight cancer. Dendritic cell-based vaccines are being explored to reactivate anti-tumor adaptive immunity. Immune checkpoint inhibitors and chimeric antigen receptor T-cells (CAR T) were however the main approaches that catapulted

Background: Long-distance migration has evolved multiple times in different animal taxa. For insect migrants, the complete annual migration cycle covering several thousand kilometres, may be performed by several generations, each migrating part of the distance and reproducing. Different life-cycle stages and preferred orientation may thus, be found along the migration route. For migrating red admi

The emulsion stabilization functionality of surfactants and biopolymers can be replaced by solid particles adsorbed at the interface, where they create a category of emulsions known as Pickering emulsions. Recently, health and environmental concerns have led to new market demand for natural, biodegradable and renewable sources of ingredients. Starch granules meet these ingredient requirements and