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Background: Thymic stromal lymphopoietin (TSLP) is released from the airway epithelium in response to various environmental triggers, inducing a type-2 inflammatory response, and is associated with airway inflammation, airway hyperresponsiveness (AHR), and exacerbations. TSLP may also induce AHR via a direct effect on airway smooth muscle and mast cells, independently of type-2 inflammation, altho

The tribe Ithomiini (Nymphalidae: Danainae) includes nearly 400 species of butterflies distributed from Mex-ico to Northern Argentina, and adults of all species are aposematic and the main models in several Neotropical mimicry rings. The subtribe Melinaeina, a small group composed of five genera of large ithomiines, is the sister group of all remaining groups in the tribe Ithomiini. With 14 recogn

BACKGROUND: Anisakis simplex, a fish parasite, causes allergic urticaria, angioedema and anaphylactic shock through an IgE-mediated hypersensitivity mechanism. Consensus on the dietary recommendations that should be given to allergic patients is lacking. Our objective was to evaluate the usefulness of different types of diets in preventing further reactions in patients allergic to A. simplex. METH

BACKGROUND. Hypoxia induces increased tumor growth by promoting angiogenic and glycolytic pathways. Tumors expressing hypoxia-inducible factor-la (HIF-1 alpha), an important transcriptional activator of oxygen-regulated genes, are resistant to chemotherapy and radiotherapy. The major challenge in prostate cancer therapy today is to gain a better understanding of the development of hormone-refracto

Trophic factors secreted both from the endocardium and epicardium regulate appropriate growth of the myocardium during cardiac development. Epicardially-derived cells play also a key role in development of the coronary vasculature. This process involves transformation of epithelia] (epicardial) cells to mesenchymal cells (EMT). Similarly, a subset of endocardial cells undergoes EMT to form the mes

Syftet med denna uppsats är att undersöka hur anställningsskyddet ser ut för arbetstagare med nedsatt arbetsförmåga (sjuka arbetstagare) i svensk rätt. Detta sker genom att med hjälp av den rättsdogmatiska metoden försöka fastställa när det kan anses vara sakligt enligt 7 § lagen (1982:80) om anställningsskydd att säga upp en sjuk arbetstagare. Nära kopplat till denna frågeställning är arbetsgivarThe purpose of this essay is to examine the employment protection for employees with reduced working ability (sick employees) in Swedish law. This is done by using the legal dogmatic method to determine when it may be considered just cause for dismissal of employment of a sick worker according to 7 § Employment Protection Act, LAS. The employer's responsibility for rehabilitation is closley li

Den svenska rättsordningen är unik i det att lagförarbeten tillmäts osedvanligt stor vikt i rättstillämpningen. Dessa har gått från att endast vara arbetsmaterial i lagstiftningsprocessen till att utgöra en viktig rättskälla i rättstillämpningen. Den svenska lagstiftningstekniken producerar kortfattade och allmänt hållna lagtexter. För att finna lagens sanna innehåll är domare och andra rättstilläThe Swedish judicial system is unique in that an unusual amount of importance is attributed to preparatory works. These have evolved from just being a law in progress to constituting one of the major sources of law in the application of such. The Swedish legislative technique tends to produce concise and general rules of law. In order to find the true meaning of the law, judges and other legal pra