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Popular Abstract in Swedish Transformationen av läkemedel till "pro-drugs" är ett lockande koncept där man tillåts förändra en förenings kemiska och fysikaliska egenskaper utan att ändra den aktiva molekylens struktur. Vilken förening som helst kan i princip omformas till en "pro-drug". Många naturprodukter besitter egenskaper som är potentiellt intressanta för behandling av sjukdom men är svåra aThe modification of drugs into pro-drugs is an attractive concept allowing you to tweak the chemical and physical properties of a drug without changing the original structure of the active compound. In principle, any compound possessing a preferred biological activity can be transformed into a pro-drug. Many natural products harbor qualities that are potentially interesting as drugs but difficult

Popular Abstract in Swedish Det doktorandarbete som framläggs av Pawel Brühl handlar om flera aspekter av ett framgångsrikt genomfört bullerskyddsarbete i en stor svensk industri med mycket hög bullernivå (Volvos pressverk i Olofström). Man har genomfört ett program bestående av bullermätningar, bullerreduktion med flera metoder samt studium av automatiseringens konsekvenser. Arbetstagarna har fåt

Popular Abstract in Swedish Modellering och krav för automation av gradningsprocessAn increasing number of robots have been used for the finishing of castings during recent years. This is mainly due to developments to overcome problems that restricted their use during the past decade. The major difficulties have been the need to control reaction forces during metal removing by grinding operations and the lack of tools designed specially for robots. The elimination of these two p

In their natural habitats, bacteria and plants can be exposed to abiotic stresses such as drought, high salt concentrations and freezing, which are factors limiting their capacity for growth and proliferation. To withstand environmental stresses, they have evolved specific stress responses. These responses include physiological adaptations, alterations in gene expression and production of protecti

This thesis is divided into two parts in which two different aspects of the Large Hadron Collider (LHC) Project are discussed. The first part describes the design of a transition radiation tracker (TRT) for the inner detector in ATLAS. In particular, the barrel part was studied in detail. The barrel TRT consists of 52 544 1.5-m-long proportional tubes (straws), parallel to the beam axis and each

Marine endotherms in the polar regions face a formidable thermal challenge when swimming in cold water. Hence, they use morphological (fat, blubber) adjustment and peripheral vasoconstriction to reduce demands for heat production in water. The animals then regain normothermia when resting ashore. In the king penguin (Aptenodytes patagonicus) metabolic rate is lower in fed than in fasted individual

Both current and historical settlement forms experience evolutionary, permanent changes to their spatial and socio-economic attributes, not seldom accompanied by dynamic functional transformations. The linkage between functionalism and dynamism, in turn, is one of those elements of conventional geographical theory used to explain the phenomena of urbanization and urbification. While urbanization r

Examensarbetets titel: We plan to win - En fallstudie om Svenska Hockeyklubbar och dess ekonomistyrning Seminariedatum: 2:a Juni 2021 Ämne/kurs: FEKH69 - Examensarbete kandidatnivå i redovisning; 15 högskolepoäng. Ekonomihögskolan vid Lunds Universitet Författare: Clara Herberts, Emma Wiklund och Olivia Bladh Handledare: Gert Paulsson Fem nyckelord: Elithockey, Ekonomistyrning, Mål, Vision, SHL SyTitle: We plan to win - En fallstudie om Svenska Hockeyklubbar och dess ekonomistyrning Seminar Date: June 2:nd 2021 Course: FEKH89 Authors: Clara Herberts, Emma Wiklund och Olivia Bladh Advisor: Gert Paulsson Key words: Elite hockey, Financial management, Goals, Vision, SHL Purpose: The purpose of the study is to process how organisations within the sport industry can use financial management to

Immunophenotypic characterization and molecular analysis have long been used to delineate heterogeneity and define distinct cell populations. FACS is inherently a single-cell assay, however prior to molecular analysis, the target cells are often prospectively isolated in bulk, thereby losing single-cell resolution. Single-cell gene expression analysis provides a means to understand molecular diffe

Diiron complexes bearing redox active diamine ligands have been studied as models of the active site of [FeFe]-hydrogenases. Heating [Fe2(CO)6(μ-edt)] (edt = 1,2-ethanedithiolate) with 2,2′-bipyridine (2,2′-bipy) or 1,10-phenanthroline (1,10-phen) in MeCN in the presence of Me3NO leads to the formation of [Fe2(CO)4(κ2-2,2′-bipy)(μ-edt)] (1-edt) and [Fe2(CO)4(κ2-1,10-phen)(μ-edt)] (2-edt), respecti

Retail and place have always been in a dynamic interrelation throughout the history. However particularly in the last three decadesthere have been some radical shifts in the outcomes of this interrelationship. The spatial formation of stores, shopping streets,malls, and in turn, cities have dramatically changed. These contemporary shifts, formations and transformations in the retailgeographies hav

Little is known about the long-term consequences of anorexia nervosa (AN) in terms of possible brain neuronal injury. We aimed at investigating whether women with adolescent-onset AN exhibit increased serum levels of neurofilament light chain protein (NfL), a biomarker for neuronal injury, compared with matched controls at 30-year follow-up. Blood samples were collected from 34 women with adolesce