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Assessment of lumbar radicular pain. Validity and predictive value of clinical tests

Popular Abstract in Swedish Kroniska ländryggsbesvär är en ekonomisk belastning för sjukvården och samhället i stort, och ger framför allt ett personligt lidande för den drabbade. Nästan alla (75-80 %) kommer att ha åtminstone en episod med ryggbesvär någon gång under sin livstid. Hälften av dessa kommer att ha utstrålande bensmärtor och ofta är besvären ett symtom på ischias (nervrotspåverkan). MRadicular pain is in the majority of cases caused by a disc herniation with a coexisting inflammation. It is characterized by positive neural tension tests, such as the Slump test, and by decreased range of motion (ROM) in the straight leg raising test (SLR) and lumbar flexion (Fingertip-to-floor test[FTF]). This may suggest that improvement in ROM correlates to reduction of self-reported disabili

Optimization of image quality and radiation dose in neuroradiological computed tomography

Background: The goal of clinical computed tomography (CT) is to produce images of diagnostic quality using the lowest possible radiation exposure. Degradation of image quality, with increased image noise and reduced spatial resolution, is a major limitation for radiation dose reduction in CT. This can be counteracted with new post-processing image filters and iterative reconstruction (IR) algorith

Omics Techniques Applied to Diabetes Research - Focus on HSL-Null Mice and Clonal β-Cells

Diabetes mellitus is a disease characterized by increased blood glucose levels. For overt type 2 diabetes to develop, both insulin action and insulin secretion must be perturbed. In the work presented in this thesis, two models were analyzed: hormone-sensitive lipase (HSL) null mice and a pancreatic clonal β-cell line to study the mechanisms underlying insulin resistance and insulin secretion pert

Självförvållad berusning och skuldprincipen - En jämförelse mellan svensk och tysk rätt

Syftet med denna uppsats är att redogöra för regleringen av självförvållad berusning i svensk och tysk straffrätt, och dess förhållande till grundläggande straffrättsliga principer. Utmärkande för problematiken kring självförvållad berusning är stridigheterna mellan kriminalpolitiska effektivitetsskäl å ena sidan, och den grundläggande straffrättsliga skuldprincipen å andra sidan. I svensk rätt reThe aim of this essay is to investigate the regulation of self-induced intoxication in Swedish and German criminal law and its relation with fundamental rule of law-principles. Characteristic for this problematic area is the incompatibility between the legislator’s criminal policy on the one hand, and fundamental rule of law principles as the principle of culpability on the other hand. In Swedish

Utredningsskyldigheten och asylsökande ensamkommande barn

Kronologisk ålder utgör en viktig del av en persons identitet och i västvärlden är det en självklarhet att alla känner till sin ålder. Så är det dock inte fallet för personer som kommer från vissa länder i mellanöstern där födelseregister oftast inte existerar och där det är högst ovanligt att någon firar sin födelsedag. Just från mellanöstern kommer många ensamkommande barn till Sverige och ansökChronological age is an important part of every person’s identity and in the Western communities it is given that everyone knows how old they are. However, it is not the case for people coming from certain countries in the Middle East where birth records do not exist and where it is highly unusual for someone to celebrate a birthday. Many unaccompanied children from, Middle East apply for asylum i

Development of a co-culture system for studies of airway epithelial and dendritic cell interactions

The interactions between airway epithelial cells (AECs) and dendritic cells (DCs) play an important role in the sensitization towards airborne allergens. Not much is known about the underlying mechanisms and novel in vitro approaches are needed, which include the different involved cell types in order to investigate what happens at the molecular level during sensitization. In this project, one aim

How to meet security standards as a cloud provider - A journey set out to clear the sky of cloud security and certifications

An upcoming trend in the current IT-landscape is to outsource services to so called Cloud Service Providers (CSPs). However, many companies are still sceptical to this new kind of services, since they bring about a certain loss of control. For this reason, it is important for CSPs to show that their services are secure. There are several options in proving this and it is up to every CSP to choose

Assisterad befruktning och rättsligt föräldraskap - Om ställningstaganden och normer som regelverken bygger på

Ofrivillig barnlöshet är ett problem som kan bero på många olika faktorer. Ett sätt för att avhjälpa den är att genomgå assisterad befruktning. Assisterad befruktning inom svensk hälso- och sjukvård är däremot inte tillgängligt för alla. För att få genomgå en behandling krävs det att vissa villkor är uppfyllda. En av dessa förutsättningar är att den assisterade befruktningen utförs på en kvinna soInvoluntary childlessness can be a problem caused by many different factors. One way to remedy is to undergo assisted reproduction. However, assisted reproduction within the Swedish healthcare is not available for everybody. Certain conditions need to be met for a person to be eligible for treatment. One of these conditions is that the woman who is going to undergo the assisted reproduction is tog

Screening for anti-allergic properties of probiotic lysates - For the down-regulation of Th2-secreted cytokines in humans suffering from Allergic rhinitis

Allergic rhinitis is a common disease affecting millions of people worldwide. Biocare Copenhagen A/S, a Danish biotechnology company decided to screen a number of probiotic lysates, with the aim to identify suitable strains with potential anti-allergic properties, that could regulate production of cytokines and divert the immune system in a regulatory or tolerant mode. People suffering from aller

Impact Investing in Kenya: An Assessment of Practises and Potential

Background There is a widespread consensus that aid alone will not be able to solve the development challenges facing Africa, with Kenya being no exception. The challenges are simply too great. One potential way to facilitate growth while also making it more inclusive is to use impact investing. Impact investing could be defined as investments made with the intention of yielding a financial return

Effekter på bostadsmarknaden av stabiliseringspolitiska åtgärder

En aktuell debatt i svensk politik är hushållens växande skulder, framför allt i storstadsområdena. Förslag har lagts fram från Finansinspektionen och Sveriges Riksbank om amorteringskrav, skuldkvotstak och sänkt ränteavdrag. Detta för att hämma en eventuellt fortsatt ökning av hushållens skulder. Den svenska hushållssektorns ökande skuldsättning tillskrivs främst de lägre kostnaderna för bolån soA current topic in Swedish politics is the increasing household debt, particularly in the metropolitan areas. The Swedish Central Bank and the Financial Supervisory Authority have made proposals for several policies, to inhibit a continued growth of the household debt. These policies include introducing amortization requirements, a debt-to-income ratio limit and reduced home mortgage interest dedu

Evaluating Off-the-shelf Hardware for Indoor Positioning

An indoor positioning system (IPS) is a system to locate objects in indoor environments using radio waves, magnetic fields, acoustic, optical and video signals or other sensory information with help of a number of known reference positions. Nowadays, indoor positioning based services are used in a wide variety of areas and indoor positioning is getting considerable attention from both research and

Hör, ni som har öron: En studie av samtalets funktion för nutida predikan

The purpose of this practical theological master’s thesis is to examine conversation as part of sermon preparation in present day preaching in the Lutheran Church of Sweden. This study combines studies of homiletical literature with qualitative empirical methods, stating that theory and practice informs one another. Through participant observation in Bible study groups and the following Sunday’s s

Comparison of various concatenated convolutional code ensembles under spatial coupling

A big challenge faced by the digital communication world today is increasing the reliability of information which is being transmitted. During the transmission of information, there is a possibility that the information is corrupted or distorted. If this distortion is considerably high, it becomes dicult to decode and retrieve the original information. To help mitigate this eect, the information b

Human neural stem cells: region-specific properties and prospects for cell therapy

Popular Abstract in Swedish Stroke är en sjukdom som främst drabbar äldre och är den största anledningen till att människor får olika slags handikapp såsom förlamning och afasi. Det finns ännu ingen effektiv behandling för att lindra symtom och lidande efter en stroke, förutom rehabilitering, och därför kostar stroke samhället enormt mycket pengar. Befolkningen blir allt äldre, vilket även medför Cell replacement by neural transplantation can, in animal models of neurodegenerative diseases, reconstruct damaged brain circuitry. In the clinical situation, the graft material used for cell therapy must, most likely, be of human origin. The human fetal brain is one potential source of neural stem cells (NSCs) for cell replacement therapy in neurodegenerative disorders such as stroke. Stroke is

Hyperpolarized 3He-diffusion MRI in evaluation of lung structure in emphysema. Validation and development of the method

Abstract COPD is a major cause of chronic morbidity and mortality throughout the world. It is a preventable and treatable disease. Smoking is the most commonly encountered risk factor for COPD and the habit now unfortunately starts at earlier ages than before. There is a strong necessity to diagnose COPD in early stages before symptoms present themselves. MRI with hyperpolarized 3He using diffusio