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Site-level model intercomparison of high latitude and high altitude soil thermal dynamics in tundra and barren landscapes

Ionization-site effects on the photofragmentation of chloro- and bromoacetic acid molecules

Simulation of CO2 and Attribution Analysis at Six European Peatland Sites Using the ECOSSE Model

Tumor Targeting Using Affibody Molecules: Interplay of Affinity, Target Expression Level, and Binding Site Composition.

Quantitative assessment of the antiviral potencies of 21 shRNA vectors targeting conserved, including structured, hepatitis B virus sites

Variability in exchange of CO2 across 12 northern peatland and tundra sites

A new route towards colloidal molecules with externally tunable interaction sites.

Efficient characterization of retro-, lenti-, and foamyvector-transduced cell populations by high-accuracy insertion site sequencing

The identification of unknown genomic flanking DNA sequences can be used for the molecular monitoring of retro-, lenti- and foamyviral integration, transgenes in early embryogenesis, insertional mutagenesis, cell fate, and stem cell plasticity. Most existing methods reflect shortcomings in sensitivity and or specificity, thus limiting genomic sequencing of unknown flanking DNA to clonal preparatio

Analysis of regulatory phosphorylation sites in ZAP-70 by capillary high-performance liquid chromatography coupled to electrospray ionization or matrix-assisted laser desorption ionization time-of-flight mass spectrometry

The adapter protein APS associates with the multifunctional docking sites Tyr-568 and Tyr-936 in c-Kit.

The adapter protein APS has previously been shown to be involved in recruiting the ubiquitin E3 ligase c-Cbl to the insulin receptor, the platelet-derived growth factor b-receptor and the erythropoietin receptor, leading to increased degradation of the receptors and inhibition of mitogenesis. Here we demonstrate, by use of immobilized synthetic phosphopeptides corresponding to various autophosphor

Dynamics of water molecules in the active-site cavity of human cytochromes P450

Identification of Csk tyrosine phosphorylation sites and a tyrosine residue important for kinase domain structure

Redox potentials of the blue copper sites of bilirubin oxidases

Does nest site availability limit the density of hole nesting birds in small woodland patches?

Geometry, Reduction Potential, and Reorganization Energy of the Binuclear CuA Site, Studied by Density Functional Theory

Pollen analysis, chronology and palaeomagnetism of three Late Weichselian sites in southern Sweden

Popular Abstract in Swedish Pollenanalys, kronologi och paleomagnetism på tre senglaciala lokaler i södra Sverige Senglaciala sjösediment (d.v.s. avsatta under slutet av den senaste istiden) från tre bassänger i södra Sverige, Torreberga i Skåne, Farslycke i Blekinge och Bolmen i Småland, har studerats med avseende på pollensammansättning och paleomagnetism. Åldersbestämning och tidsjämförelser b

Identification of a Ser/Thr cluster in the C-terminal domain of the human prostaglandin EP4-R essential for agonist-induced beta-arrestin1 recruitment that differs from the apparent principal phosphorylation site.

hEP4-R (human prostaglandin E2 receptor, subtype EP4) is a Gs-linked heterotrimeric GPCR (G-protein-coupled receptor). It undergoes agonist-induced desensitization and internalization that depend on the presence of its C-terminal domain. Desensitization and internalization of GPCRs are often linked to agonist-induced b-arrestin complex formation, which is stabilized by phosphorylation. Subsequentl

Screening the molecular surface of human anticoagulant protein C: a search for interaction sites

Protein C (PC), a 62 kDa multi-modular zymogen, is activated to an anticoagulant serine protease (activated PC or APC) by thrombin bound to thrombomodulin on the surface of endothelial cells. PC/APC interacts with many proteins and the characterisation of these interactions is not trivial. However, molecular modelling methods help to study these complex biological processes and provide basis for r

Prospects for a regional assessment of forest soil chemistry dynamics in Croatia: Application of the SAFE model to a forested site in the region of Mt. Medvednica

Unusual CO adsorption sites on vanadium oxide-Pd(111) "inverse model catalyst" surfaces

The morphology, structure, and reactivity of vanadium oxide-decorated Pd(111) surfaces, which have been subjected to oxidation and reduction treatments, have been investigated by scanning tunneling microscopy (STM), high-resolution electron energy loss spectroscopy (HREELS), and high-resolution X-ray photoelectron spectroscopy (HR-XPS) with synchrotron radiation combined with ab initio density fun