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Studies on the interaction between vitamin K-dependent protein S and complement regulator C4b-binding protein: localization of binding sites and identification of a possible function of the complex.

Complement is a cascade-like system that is part of the innate immune defence. It is an explosive system, potentially harmful also for the host cells, and needs to be strictly regulated. An important down-regulator of complement is C4b-binding protein (C4BP). C4BP contains two different types of subunits, seven identical a-chains and one unique P-chain. The alpha-chains bind to C4b, C4BP's target

Interspecific variation in hatching success among three sea duck species at one breeding site in the Baltic Sea

Understanding variation in survival and reproduction is key for conservation and management of bird populations. By compiling and analysing data on hatching success (i.e. proportion of nests with at least one hatched egg) from Common Eider Somateria m. mollissima, Velvet Scoter Melanitta fusca and Red-breasted Merganser Mergus serrator, all breeding on a single island in the Baltic Sea, we demonst

The stereospecific interaction sites and target specificity of cGMP analogs in mouse cortex

cGMP interactors play a role in several pathologies and may be targets for cGMP analog-based drugs, but the success of targeting depends on the biochemical stereospecificity between the cGMP-analog and the interactor. The stereospecificity between general cGMP analogs—or such that are selectivity-modified to obtain, for example, inhibitory actions on a specific target, like the cGMP-dependent prot

Beyond site/sight : Culural spaces and the conditions of creativity

My written contribution responds to the questions: How des your practice relate to placemaking? How is it possible to use sense of place as material and starting point for research or artistic work? What methods do you use for co-creation and relationship building in relation to place?

Binding of monoclonal IgM rheumatoid factor to streptococci via the antibody combining site

Radiolabelled monoclonal IgM rheumatoid factors, four from patients with type II essential cryoglobulinaemia and one originating from a patient with rheumatoid arthritis, were tested for binding to group A, B, C and G streptococci and Escherichia coli. Two of the preparations exhibited different binding patterns for the streptococci, whereas the remaining three were not reactive. The binding of on

Modalities of Place: On Polarisation and Exclusion in Concepts of Place and in Site-Specific Art

In this thesis the notion of place is studied by way of investigating the “non-place” which is excluded or opposed, whenever a place is defined. “Non-place” is used here as a meta-concept, covering various recurring types of opposition to “place,” and it therefore represents a profoundly incoherent spect-rum of realities and concepts. Hence, a “non-place” may in this investigation appear as “lefto

A Heterobimetallic FeIIIMnII Complex of an Unsymmetrical Dinucleating Ligand: A Structural and Functional Model Complex for the Active Site of Purple Acid Phosphatase of Sweet Potato

The heterodinuclear mixed-valence complex [FeMn(ICIMP)(OAc)(2)Cl] (1) {H2ICIMP = 2-(N-carboxylmethyl)-[N-(N-methylimidazolyl-2-methyl)aminomethyl]-[6-(N-isopropylmethyl)-[N-(N-methylimidazolyl-2-methyl)]aminomethyl-4-methylphenol], an unsymmetrical N4O2 donor ligand} has been synthesized and fully characterized by several spectroscopic techniques as well as by X-ray crystallography. The crystal st

Glass, alcohol and power in Roman Iron Age Scotland - a study of the Roman vessel glass from non-Roman/native sites in north Northumberland and Scotland

Popular Abstract in Swedish Denna avhandling bygger på ett studium av romerska glaskärl funna på icke-romerska/inhemska fyndorter — huvudsakligen tillhörande den romerska järnåldern (0–400 e.Kr.) — bortom Hadrianus mur i norra Britannien. Romerska glaskärl har påträffats på inalles 60 fyndorter, varav en stor del utgörs av bosättningar av skilda slag, och endast en liten del härrör från gravar. So