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Genetic alterations underlying the development of the cancer of the nose and paranasal sinuses (sinonasal cancer, SNC), a rare cancer that can be included in the group of head and neck cancers, are still largely unknown. We recently reported that TP53 mutations are a common feature of SNC, with an overall frequency of 77%, and they show association to adenocarcinoma and wood-dust exposure [15]. In
The distribution of neuropeptide Y (NPY)-immunoreactivity was investigated in the rabbit maxillary sinus and adjacent ganglia. A moderate supply of NPY-containing nerve fibers occurred around seromucous glands and a denser supply around small blood vessels. Only a few immunoreactive nerve fibers were seen beneath the epithelium. Double immunostaining showed that vasoactive intestinal peptide (VIP)
As their most critical limitation, neighborhood and health studies published to date have not taken into account nonresidential activity places where individuals travel in their daily lives. However, identifying low-mobility populations residing in low-resource environments, assessing cumulative environmental exposures over multiple activity places, and identifying specific activity locations for
The use of folic acid prior to conception is generally recommended for the prevention of birth defects, notably neural tube defects. In a previous study from Sweden, based on interviews of women in early pregnancy, no such effect was found on the general malformation rate, but data for neural tube defects were scarce. Using data from the Swedish Medical Birth Register for the years 1995-2004, 20 8
Purpose – To identify and describe the strategic potential of logistics-driven packaging innovation in retail supply chains, and suggest propositions for further research and development, providing practitioners with a better basis on which to make strategic packaging and logistics decisions. Design/methodology/approach – An in-depth case study was conducted at a large global retailer which had im
Popular Abstract in Swedish Enzymer är viktiga ämnen i naturen. Vi talar då och då om att vi förbränner vår mat. Trots detta känner vi oss oftast inte särskilt varma, i alla fall inte så att det bränns. Visst bränner vi vår mat. Socker omvandlas till koldioxid och vatten precis som om vi hade eldat upp det utanför kroppen. Skillnanden är att kroppen omvandlar sockret långsammare och mer kontrollerWith the goal to study the mechanisms of dinuclear metalloenzymes, a new line of synthetic and computational models were prepared and studied. Mixed imidazole and carboxylate multidentate complexes were synthesized to better simulate carboxylate-rich ligand environments. Of the compounds, which showed to be the most useful, were one symmetric and the other one asymmetric and in both cases they wer
A virtual reality (VR) experiment with 96 participants was carried out in a Cave Automatic Virtual Environment (CAVE) laboratory at Lund University to provide recommendations on the design of flashing lights at emergency exit portals for road tunnel emergency evacuation. A set of variables were investigated, namely 1) Colour of flashing lights, 2) Flashing rate, 3) The type of light source, 4) The
In a time full of environmental changes the need for understandings of the operational work and services, the control of the business and key figures, and flexibility to adapt to different circumstances is crucial in many organizations. In a time where national borders are getting more and more invisible and where the humans are traveling and moving more than ever it is even more important to have
Due to the development of technology, the value of the IP protected goods increases, and so does the harm done by the infringers. The TRIPS Agreement expressly provides for criminal sanctions for the serious cases of trademark counterfeiting and copyright piracy where the offences are committed willfully and on commercial scale. The TRIPS Agreement also reserves a possibility for introduction of m
