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Parkinson’s disease (PD) is a progressive neurodegenerative disorder, characterized by tremor, muscle rigidity and bradykinesia, which is primarily due to the degeneration of nigrostriatal dopaminergic neurons. Currently, patients are primarily treated with L-dopa and other drugs that enhance dopaminergic function. Those are effective during the first years, but eventually the majority of patients

Metallurgical debris is by far the most informative source material for studying the metal craftsmanship of the past. In comparison to the finished objects, which has attracted far more attention in archaeological research, debris material are more or less confined to the original workshop sites and hence provide direct evidence as to production volume and quality, site organization, artisanal ski

Anaerobic digestion (AD) has gained increasing attention nowadays as an approach for both waste treatment and renewable energy generation. Currently, many different types of materials can be used as feedstock for biogas production via AD process, but their biodegradability (based on methane yield, BDCH4) and potential to produce biogas might vary significantly, and these properties are key paramet

Conceptual design is the first phase in the design process in which all the requirements and design objectives are synthesized into conceptual alternatives. In practice today, major decisions regarding the buildings geometry, massing, and overall form are usually made during the first phase. Considering structural performance requirements during conceptual design enhances interdisciplinary interac

This thesis deals with the development of the EU asylum law and policy with focus on the role of burden-sharing and temporary protection. The Geneva Convention is the legal framework for community action. This is laid down by Article 63.1 of the EC Treaty. Article 63 does not only refer to the Geneva Convention, but also to other relevant Human Rights Treaties such as the 1948 Universal Declaratio

Coordinated inventory control is a concept within inventory management where decisions are based on stock and demand situations throughout a whole system of interconnected warehouses and inventories, and where control parameters are simultaneously determined and set at all installations. This thesis is a part of a larger research collaboration project in coordinated inventory control where NGiL (N

Den internationella arenan domineras av stater. Staters existens är befäst i sedvanerätten genom Montevideokonventionen. Det har dock i ivern att hålla sig fast vid denna uppstått en uppfattning om att de kriterierna som krävs för att något kan anses vara en stat, också blir gällande e contrario i hänsyn till när stater ska anses upphöra att existera. En av de fyra kriterierna är kriteriet om terrThe global arena is dominated by states. The existence of a state is regulated in the Montevideo Convention on the Rights of States. There does however seem, that in the desire to follow this convention, a definitive opinion that states losing one of the criteria set up by the convention, also means losing their stateship, as a Montevideo Convention e contrario, if you will. One of these four crit

Studying knowledge-intense regional development from the perspective of classified periphery fills an identified gap in analysis and practice. It illustrates challenges, possibilities, and nuances current trajectory of centre-peripheral development. Exploring role and perspective of peripheral areas within regions, and thus marginalized places, can help increase cohesive, instead of fragmented, re

GABAergic Neurotrasmission – A “cross-talker” between inflammation and neural plasticity in stroke Stroke is a leading cause of disability and no pharmacological treatment is currently available to promote recovery in suffering patients. A major part of research is focusing on finding new biological targets which can be pharmacologically intervened with, providing favorable results in facilitatin

Should I stay or should I go? Every year billions of animals migrate! For different reasons, to different places and different distances but they all have the act of migration in common. In almost all groups of animals migration have evolved time and time again. This raises the question of how and why migration came to be? One possible answer is that it evolved from partial migration, where only

Gut microbiota play a central role in metabolism for example in blood glucose homeostasis and appetite regulation. This thesis provides a prospect of using the bacterium Prevotella copri as a probiotic to help maintain a healthy gut microbiota as many evidences points towards probiotics to have a great potential as preventative agents or therapeutics for type 2 diabetes. In the first part of the tAccording to the World Health Organization (WHO) nearly 8.5% of the global population is affected by metabolic diseases such as type 2 diabetes and obesity which are one of the major causes of death and disability worldwide. This causes a huge financial burden on the healthcare system globally. Therefore, there is an urgent need to prevent, delay and treat these diseases and their debilitating com

Norra Djurgårdsstaden är ett stadsutvecklingsområde i nordöstra Stockholm och har delvis marksanerats ned till grundvattennivån. De föroreningar som förekommit är polycykliska aromater, cyanider, tungmetaller och BTEX. 2003 inleddes en omfattande markundersökning varpå man hittade höga halter bensen i ett av grundvattenrören. Undersökningen följdes upp med ett in-situ försök att avlägsna förorenin

The aim of this project was to examine if it is feasible to develop and apply a reuse concept regarding clean in place (CIP) processes. The concept is based on different topics such as lim-itation, structure, future and reliability. Three CIP processes were chosen to represent the wide variety of cleaning processes available to the food and pharmaceutical industries, Single use Food, Recovery Food

At the IT department of IKEA, test specialists who are responsible for software testing are currently using a suite from Hewlett Packard called HP Application Lifecycle Management that includes an analysis tool for test result evaluation. During the implementation of this thesis work, the real world demand for a replacement of the analysis tool became apparent, as the interface of the analysis too

Airborne diseases are spread when droplets containing pathogens, viruses and/or bacteria, are expelled into the air due to coughing, sneezing or talking. These droplets, or aerosols, can remain suspended in the air for quite some time in contained environments. Diseases are also transmitted by close physical contact and by rubbing eyes, mouth and nose after touching a contaminated surface. Radica

Purpose -- The overall purpose of this study is to enhance the understanding of customer perceived service quality within grocery retailing in a North European context. We do this by comparing customer perceived service quality evaluations of the traditional supermarket store with evaluations of the discount store. Design/methodology/approach -- This study is based on empirical data from four stor

Popular Abstract in Swedish Hjärt- och kärlsjukdomar är den största enskilda orsaken till en för tidig död i västvärlden. För att öka kunskapen om dessa sjukdomar är det viktigt att finna mätmetoder, gärna icke-invasiva, som kan användas för att studera tidiga yttringar av hjärt- och kärlsjukdomar. Förändringar av de mekaniska egenskaperna i artärerna kan vara en sådan tidig yttring. För att få etCardiovascular diseases constitute the major cause of morbidity and mortality in the Western World. To increase our knowledge of cardiovascular diseases, it is important to find methods, preferably non-invasive ones, to study very early manifestations of vascular disease. Changes in the mechanical properties of the arteries can be an early manifestation of vascular disease. Further, changes in the