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Discordant amyloid-β PET and CSF biomarkers and its clinical consequences

Injury severity prediction of cyclist crashes using random forests and random parameters logit models

Cycling provides numerous benefits to individuals and to society but the burden of road traffic injuries and fatalities is disproportionately sustained by cyclists. Without awareness of the contributory factors of cyclist death and injury, the capability to implement context-specific and appropriate measures is severely limited. In this paper, we investigated the effects of the characteristics rel

Coronary microvascular dysfunction in Takotsubo syndrome and associations with left ventricular function

Exposure to long-term source-specific transportation noise and incident breast cancer : A pooled study of eight Nordic cohorts

Maternal separation differentially modulates early pathology by sex in 5xFAD Alzheimer’s disease-transgenic mice

Gaia Data Release 3: Chemical cartography of the Milky Way

Long-Term Oxygen Therapy for 24 or 15 Hours per Day in Severe Hypoxemia

Melanoma Incidence and Mortality Trends in Sweden

Gaia Data Release 3: Properties and validation of the radial velocities

Context. Gaia Data Release 3 (Gaia DR3) contains the second release of the combined radial velocities. It is based on the spectra collected during the first 34 months of the nominal mission. The longer time baseline and the improvements of the pipeline made it possible to push the processing limit from GRVS= 12 in Gaia DR2 to GRVS= 14 mag. Aims. We describe the new functionalities implemented for

Computing irregular hypar-based quad-mesh patterns for segmented timber shells

Hyperbolic paraboloids, “hypars,” are special types of ruled surfaces. Their geometric properties provide them with loadbearing and stabilizing capacities, as well as distinct esthetic qualities. These attributes become evident in numerous applications in buildings, in many of which concrete or timber is used for the construction of the hypars. Hypars could also be relevant in the context of circu

Red cell distribution width and its polygenic score in relation to mortality and cardiometabolic outcomes

Transnasal Evaporative Cooling in Out-of-Hospital Cardiac Arrest Patients to Initiate Hypothermia—A Substudy of the Target Temperature Management 2 (TTM2) Randomized Trial

Atopic dermatitis, systemic inflammation and subsequent dementia risk

Retrospective validation study of an artificial neural network-based preoperative decision-support tool for noninvasive lymph node staging (NILS) in women with primary breast cancer (ISRCTN14341750)

Background: Surgical sentinel lymph node biopsy (SLNB) is routinely used to reliably stage axillary lymph nodes in early breast cancer (BC). However, SLNB may be associated with postoperative arm morbidities. For most patients with BC undergoing SLNB, the findings are benign, and the procedure is currently questioned. A decision-support tool for the prediction of benign sentinel lymph nodes based

Hounsfield Unit-Calculated Bone Mineral Density Loss Following Combat-Related Lower Extremity Amputations

Higher target attainment for B-lactam antibiotics in patients with Gram-negative bloodstream infections when four times actual minimum inhibitory concentrations and epidemiological cutoff values are applied compared to clinical breakpoints

Flooding and erosion of coastal roads - exposure, mitigation and climate change impact

The coastal zone is a dynamic region where the sea meets land, making it highly influenced by environmental conditions such as storm surges, extreme weather events, and coastal erosion. Coastal areas are also characterized by high population densities, significant urban development, and important socio-economic functions such as transportation, trade, tourism and recreation. Consequently, they are

Holocene land cover change in North America : Continental trends, regional drivers, and implications for vegetation-atmosphere feedbacks

Land cover governs the biogeophysical and biogeochemical feedbacks between the land surface and atmosphere. Holocene vegetation-atmosphere interactions are of particular interest, both to understand the climate effects of intensifying human land use and as a possible explanation for the Holocene temperature conundrum, a widely studied mismatch between simulated and reconstructed temperatures. Prog

RET inhibition overcomes resistance to combined CDK4/6 inhibitor and endocrine therapy in ER+ breast cancer

Nutritional quality of diet characterized by the Nutri-Score profiling system and cardiovascular disease risk : a prospective study in 7 European countries