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The quality movement: where are you going?

The aim of this article is to reflect on the evolution of total quality management (TQM) as the most widespread quality management approach during the last 25 years. However, during the first 10 years of the new millennium, the term TQM seems to have lost its attractiveness in Western parts of the world and instead new terms such as Business Excellence, Organisational Excellence, Six Sigma, and Le

Platinum Interference with siRNA Non-seed Regions Fine-Tunes Silencing Capacity.

Knowledge concerning the molecular mechanisms governing the influence of non-coding RNAs on protein production has emerged rapidly during the past decade. Today, two main research areas can be identified, one oriented toward the use of artificially introduced siRNAs for manipulation of gene expression, and the other one focused on the function of endogenous miRNAs. In both cases, the active molecu

Assessing atmospheric nitrogen deposition to natural and semi-natural ecosystems - Experience from Danish studies using the DAMOS

Local agricultural emissions contribute significantly to the atmospheric reactive nitrogen loads of Danish terrestrial ecosystems. In the vicinity of the sources this may be up to 6-8 kg N ha(-1) yr(-1) depending on location and ecosystem type. This contribution arises from dry deposition of gas phase ammonia derived from local livestock production. Long-range transport, however, often constitutes

Advances in Bone Tissue Engineering

Popular Abstract in Swedish Skador på skelettet kan uppstå efter bl.a. olyckor, tumörkirurgi eller strålning. Ofta är sådana skador mycket handikappande då de påverkar kroppens funktion, stabilitet och utseende. Om benvävnad saknas eller måste bytas ut använder man sig idag av mikrokirurgiska metoder, där man flyttar kroppseget ben från ett ställe till ett annat. Tyvärr innebär detta att man skapaBone deficiencies, caused by malformations, trauma or adverse effects from medical treatments, are a clinical challenge and often associated with reduced physical function and quality of life. Autologeous bone grafts can be used to reconstruct skeletal defects, but the right size and quality of bone might not always be available and even so, donor-site morbidity might follow. A pre-fabricated or t

Migration of Sea Turtles from Caribbean Costa Rica: Implications for Management

Popular Abstract in Swedish Fyra högst migratoriska och utrotningshotade havssköldpaddsarter (soppsköldpadda, karettsköldpadda, havslädersköldpadda och oäkta karettsköldpadda) lägger ägg i Tortuguero nationalparken i Costa Rica. Havssköldpaddsforskning har pågått fortlöpande i Tortuguero sedan Dr. Archie Carr påbörjade studier under 1950-talet. Denna avhandling avser att klargöra Tortugueros havs

Mannen i ledet. Takt och otakt i värnpliktens skugga

Popular Abstract in Swedish Från början användes uttrycket "mannen i ledet" bara om meniga soldater, men det är också ett bildligt uttryck med innebörden gemene man, gräsrot, medlem på fältet/gräsrotsnivå/verkstadsgolvet. Den här avhandlingen handlar om unga män som under mitten av 1990-talet gjorde lumpen på ett pjäskompani vid Wendes artilleriregemente i skånska Hässleholm. ”Pjäs” betyder kanoneThis dissertation deals with young men who in the mid 1990s made their military service at a cannon company at Wende’s artillery regiment in the scanian town Hässleholm. ”Cannon” refers not only to cannons, but also to haubitses, grenade-throwers and other heavy arms. The focus, however, is on cultural and social aspects of everyday military service. What does actually happen in the encounter betw

Advanced Texturing in Mobile Phone Covers

Discussion The trend on the mobile phone market indicates that mobiles with advanced texture will be in demand. Sony Ericsson Mobile Communications AB would like to examine what possibilities there are in the field for texturing. In 2006 they introduced the mobile phone W850i with advanced texture on the market and now they want to know more about different techniques for texturing in the future.

The Sustainable Future of Music Festivals: How can new policy instruments and voluntary guidance tools help music festivals become more sustainable?

Over the last decade the music festival sector grew enormously: in 2008 over a million festivalgoers gathered in the UK to share music and companionship. However in doing so musicfestivals generate large volumes of waste streams and consume large quantities of resources. Amusic festival of more than 40 000 people will produce in the order of 2000 tons of CO2e –with audience transportation and on s

Hypotekarisk säkerhet i lös egendom - tre länder, tre lösningar och svårigheten att enas

Flertalet näringsidkare är i behov av krediter när verksamheten skall startas upp eller större investeringar skall göras. Borgenären kräver här inte sällan en säkerhet för sin fordran. Huvudregeln är att handpanträtter skall traderas till borgenären. Ett problem uppstår således i de fall då näringsidkaren behöver nyttja alla sina tillgångar i den löpande verksamheten. Av denna anledning finns det The vast majority of businessmen and manufacturers are not seldom in need of credits when starting up a new business, or when making larger investments. The creditor, usually a bank, commonly requires securities for debts. A problem occurs when a debtor needs to have access to all his assets in the ongoing business. He is therefore not able to transfer the assets that constitute the security. A so

A1M: a heme and radical binding protein. A study on structure, function and mechanisms

This thesis describes functional and structural studies of the human protein α1-microglobulin (A1M), an evolutionarily well-conserved 26 kDa plasma and tissue protein mainly synthesized in the liver. A1M belongs to the lipocalin protein family. Lipocalins share a very similar structur, an 8-stranded β-barrel forming a hydrophobic pocket. A1M has reductase and radical scavenging properties. A1M als

Variations in the pre-operative status of patients coming to primary hip replacement for osteoarthritis in European orthopaedic centres

Background: Total hip joint replacement (THR) is a high volume, effective intervention for hip osteoarthritis (OA). However, indications and determinants of outcome remain unclear. The 'EUROHIP consortium' has undertaken a cohort study to investigate these questions. This paper describes the variations in disease severity in this cohort and the relationships between clinical and radiographic sever

Chromosome dynamics and genomic instablity in neuroblastoma. Three genomic pillars: MYCN amplification, numerical and structural changes.

Popular Abstract in Swedish Neuroblastom är den vanligaste solida tumören, utanför hjärnan, hos små barn och finns nästan inte alls hos vuxna. Varje år insjuknar mellan femton och tjugo barn i Sverige, de flesta före två års ålder. Överlevnaden har ökat de senaste tjugo åren men är fortfarande på låga nivåer för de mer aggressiva formerna. Neuroblastom uppstår i det sympatiska nervsystemet. Därför

Calcium-induced mitochondrial permeability transition in CNS-derived mitochondria - Pharmacological aspects of specificity and toxicity in neuroprotection

Mitochondria are the main site for energy conversion in the cell. Under certain circumstances, such as excess calcium retention or production of reactive oxygen species, a pore forms at contact sites between the outer and the normally impermeable inner mitochondrial membrane. The ensuing osmotic mitochondrial swelling and loss of bioenergetic function is referred to as the mitochondrial permeabili

Reproductive function in male childhood cancer survivors

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Målet med denna avhandling var att undersöka hur cancersjukdomar i barndomen och behandlingen av dessa påverkar olika aspekter av fortplantningsförmågan i vuxen ålder. Glädjande nog har andelen patienter som överlever cancer i barndomen de senaste decennierna ökat stadigt till nivåer som idag ligger på nästan 80%. Ökad överlevnad medf