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The identification of the BTK(Bruton's tyrosine kinase) gene defective in human immunoglobulin deficiency X-Iinked agammaglobulinaemia (XLA) and characterisation of BTK exon-intron boundaries has now allowed the analysis of mutations and polymorphisms at the level of genomic DNA, Using Southern blot analysis and the polymerase chain reaction single strand conformation polymorphism (PCR-SSCP) assay

Glucose-induced insulin secretion in response to a step increase in blood glucose concentrations follows a biphasic time course consisting of a rapid and transient first phase followed by a slowly developing and sustained second phase. Because Type 2 diabetes involves defects of insulin secretion, manifested as a loss of first phase and a reduction of second phase, it is important to understand th

For 20 years, induced hypothermia and targeted temperature management have been recommended to mitigate brain injury and increase survival after cardiac arrest. On the basis of animal research and small clinical trials, the International Liaison Committee on Resuscitation strongly advocated hypothermia at 32-34 °C for 12-24 hours for comatose patients with out-of-hospital cardiac arrest with initi

Electronic health records (EHRs) are a rich source of information for medical research and public health monitoring. Information systems based on EHR data could also assist in patient care and hospital management. However, much of the data in EHRs is in the form of unstructured text, which is difficult to process for analysis. Natural language processing (NLP), a form of artificial intelligence, h

One of the greatest impediments to the use of probabilistic reasoning in legal arguments is the difficulty in agreeing on an appropriate prior probability for the ultimate hypothesis, (in criminal cases this is normally “Defendant is guilty of the crime for which he/she is accused”). Even strong supporters of a Bayesian approach prefer to ignore priors and focus instead on considering only the lik

The large spatial variability in Arctic tundra complicates the representative assessment of CO2 budgets. Accurate measurements of these heterogeneous landscapes are, however, essential to understanding their vulnerability to climate change. We surveyed a polygonal tundra lowland on Svalbard with an unmanned aerial vehicle (UAV) that mapped ice-wedge morphology to complement eddy covariance (EC) fl

PurposeThere is a growing demand for a concurrent development of product and packaging in order to better take into account the supply chain needs. Different tasks are required to integrate packaging and product development: 1) At the strategic level, it is necessary to define or refine an integrated development policy; 2) For each new development project, an adaptation of this policy must be unde

The use of external providers for the provision of information and communication technology (ICT) in small and medium-sized enterprises (SMEs) is expected to increase. At the end of the 1990s the concept of Application Service Provision (ASP) and Application Service Providers (ASPs) was introduced. This is described as one way for SMEs to provide themselves with software applications. However, it

Foreign nationals may, according to Swedish law, be placed in detention centers. That means that they are deprived of their liberty for the purpose of being accessible for the migration authorities. The person will thereby be placed in a designated premises provided by the Swedish Migration Agency, although an incapacitation in police custody or correctional facilities can also become a reality. T

Många av dem mest spektakulära händelserna som sker i vår värld kan inte ses med blotta ögat. Vid varje andetag sker miljontals reaktioner, saltkoncentrationen i cellerna regleras, signaler skickas genom kroppens nervsystem, och receptorer plockar upp signalmolekyler likt hur post skickas till brevlådan och läses av oss i hemmet. Immunförsvaret är en otroligt viktig del av vår kropp som dagligen The immune system is a very complex system, aimed to protect the body from the many dangers that loom around us. A well-functioning immune system can fight of most invaders, remove foreign particles that entered our bodies, and take care of dead cells. The aim in this work is seeing how the protein CD45 (also known as PTPRC, protein tyrosine phosphatase, receptor type, C) is affected by salt conc

Den primära frågan i uppsatsen är om säljarens upplysningsplikt gentemot köparen för fel vid försäljning av en fastighet går att definiera; för vilka typer av avvikelser har säljaren en upplysningsplikt och finns det situationer då en upplysningsplikt alltid uppstår? Upplysningsplikten finns inte uttryckligen formulerad i lag. Indirekt går det däremot att utläsa en upplysningsplikt i ett fåtal laThe primary inquiry in the thesis is whether the seller's disclosure obligation towards the buyer for property defects can be defined; For what types of defects does the seller have a duty to provide information and do situations exist in which an obligation to provide information always apply? The duty to provide disclosure is not expressly stated by law. Indirectly, on the other hand, it is

This study is a qualitative study of women who have been exposed to violence in close relationship. We have chosen to focus on how women who have been exposed to domestic violence, present themselves and the perpetrator in mass media. We are also interested of studying how these women present the consequences of the violence in mass media. The analysis is accomplished by qualitative content analys

The profane choir - finds and traces in the choir stalls of Lunds cathedral. When the choir in Lunds cathedral was being rebuilt in 1833 the choir-stalls were moved. Beneath them a surprising amount of well preserved artefacts were found. This included pencils, sandals, a large amount of coins, papers with writing and half a deck of playing cards. For almost 200 years these finds have received lit

Sverige har i över tjugo års tid, från såväl nationellt som internationellt håll, utstått omfattande kritik angående långa häktestider och en allt för liberal restriktionsanvändning. Vissa mindre förändringar har skett med tiden men de svenska problemen kvarstår i stort oförändrande än idag. I ett försök att åtgärda problemen tillsatte regeringen en utredning som presenterade sitt betänkande 2016,

Skillnader i kultur mellan länder är sedan länge väldokumenterade (Hofstede, 1998). I en allt mer globaliserad värld där det blir vanligare att personer flyttar mellan länder har det blivit aktuellt att studera huruvida dessa personer “akulturaliseras” (Berry, 2003), alltså anpassar sig kulturellt, till sin nya hemmiljö. I denna studie undersöks huruvida personer från ett land som Hofstede (1998)