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Populärvetenskaplig sammanfattning: Naturens tandemcykel – på väg att spåra ur. På senare år har det talats allt mer om klimatet och allt som ses som ett hot mot det. För växter och djur spelar de säsongsmässiga variationerna i miljöförutsättningar roll för när på året olika steg i deras utveckling sker, hur deras fenologi påverkas. I denna uppsats studeras några av de resultat av förändrad fenolo
For 20 years, induced hypothermia and targeted temperature management have been recommended to mitigate brain injury and increase survival after cardiac arrest. On the basis of animal research and small clinical trials, the International Liaison Committee on Resuscitation strongly advocated hypothermia at 32-34 °C for 12-24 hours for comatose patients with out-of-hospital cardiac arrest with initi
Electronic health records (EHRs) are a rich source of information for medical research and public health monitoring. Information systems based on EHR data could also assist in patient care and hospital management. However, much of the data in EHRs is in the form of unstructured text, which is difficult to process for analysis. Natural language processing (NLP), a form of artificial intelligence, h
Protein tyrosine phosphatases (PTPs) play an important role in cellular signaling and have been implicated in human cancers, diabetes, and obesity. Despite shared catalytic mechanisms and transition states for the chemical steps of catalysis, catalytic rates within the PTP family vary over several orders of magnitude. These rate differences have been implied to arise from differing conformational
Significance: In recent years, a number of studies have shown altered oxygen partial pressure at a tissue level in metabolic disorders, and some researchers have considered oxygen to be a (macro) nutrient. Oxygen availability may be compromised in obesity and several other metabolism-related pathological conditions, including sleep apnea-hypopnea syndrome, the metabolic syndrome (which is a set of
The identification of the BTK(Bruton's tyrosine kinase) gene defective in human immunoglobulin deficiency X-Iinked agammaglobulinaemia (XLA) and characterisation of BTK exon-intron boundaries has now allowed the analysis of mutations and polymorphisms at the level of genomic DNA, Using Southern blot analysis and the polymerase chain reaction single strand conformation polymorphism (PCR-SSCP) assay
Dramatic declines of some arthropod populations have recently received a lot of attention. Identified declines have mainly been attributed to changes in agriculture, climate, pathogen prevalence and light pollution, as well as cross-regional effects of, e.g., drifting pesticides. However, the overall picture is complex and debated, and there is a need for systematically collected long-term data, n
The use of external providers for the provision of information and communication technology (ICT) in small and medium-sized enterprises (SMEs) is expected to increase. At the end of the 1990s the concept of Application Service Provision (ASP) and Application Service Providers (ASPs) was introduced. This is described as one way for SMEs to provide themselves with software applications. However, it
Background: Nearly 18,000 individuals suffer from hip fracture in Sweden each year. The choice in operation method for femoral neck fractures has changed over the years as well as the overall management. Functional outcome after hip fracture is affected by several factors and the overall functional level for old people in Sweden has improved over the last decades. Objective: To describe and analys
The potato onion ‘Leksand’, the soapwort ‘Kvinnsgröta’, and the geranium ‘Drottningminne’ are since a few years officially authorized Swedish heritage plants. They are all named after places; a small town in Dalecarlia, a village on the island Öland and a farmstead in the northern region Jämtland. This presentation will discuss how heritage plants are made, in processes which comprise social and p
The symptoms of interstitial cystitis (IC)/bladder pain syndrome (BPS) may have multiple causes and involve many contributing factors. Traditional treatments (intravesical instillations) have had a primary focus on the bladder as origin of symptoms without adequately considering the potential influence of other local (pelvic) or systemic factors. Systemic pharmacological treatments have had modest
One of the greatest impediments to the use of probabilistic reasoning in legal arguments is the difficulty in agreeing on an appropriate prior probability for the ultimate hypothesis, (in criminal cases this is normally “Defendant is guilty of the crime for which he/she is accused”). Even strong supporters of a Bayesian approach prefer to ignore priors and focus instead on considering only the lik
PurposeThere is a growing demand for a concurrent development of product and packaging in order to better take into account the supply chain needs. Different tasks are required to integrate packaging and product development: 1) At the strategic level, it is necessary to define or refine an integrated development policy; 2) For each new development project, an adaptation of this policy must be unde
The large spatial variability in Arctic tundra complicates the representative assessment of CO2 budgets. Accurate measurements of these heterogeneous landscapes are, however, essential to understanding their vulnerability to climate change. We surveyed a polygonal tundra lowland on Svalbard with an unmanned aerial vehicle (UAV) that mapped ice-wedge morphology to complement eddy covariance (EC) fl
This collection gathers the more important instruments dealing with the relationships of business with a range of topics such as labor rights, security issues, environmental protection, anti-corruption, good governance, poverty alleviation and development, which all have important human rights dimensions. The premise for this selection is that business has both responsibilities and opportunities t
The accumulation of empirical evidence that outward-oriented developing countries have generally performed better than inward-oriented ones in terms of growth, industrialisation, job creation and other macroeconomic indicators provides an essential lesson for both policy-makers and development economists worldwide. The acknowledged importance of trade and non-traditional exports for development an
