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1. The effects of antimalarial drugs on the intracellular signaling leading to activation of the phospholipase C and phospholipase A2 pathways and the induction of proinflammatory cytokines have been studied in mouse macrophages. 2. Both chloroquine and quinacrine, and to a lesser extent hydroxychloroquine, inhibited arachidonate release and eicosanoid formation induced by phorbol diester. This in

In the teacher education programme at Halmstad University, Sweden, the supervision and examination of the students’ degree papers recently changed. Groups of students are now supervised by supervisor pairs, who in turn are part of a team that is coached by a colleague. The examination of the degree papers has also changed, in that the examination is conducted by someone outside the supervising tea

Despite recent technological advancements allowing the characterization of cancers at a molecular level along with biomarkers for cancer diagnosis, the management of ovarian cancers (OC) remains challenging. Proteins assume functions encoded by the genome and the complete set of proteins, termed the proteome, reflects the health state. Comprehending the circulatory proteomic profiles for OC subtyp

In ecology, multifunctionality metrics measure the simultaneous performance of multiple ecosystem functions. If species diversity describes the variety of species that together build the ecosystem, multifunctionality attempts to describe the variety of functions these species perform. A range of methods have been proposed to quantify multifunctionality, successively attempting to alleviate problem

Hereditary CNS amyloid angiopathy occurring in Icelanders is the first human disorder known to be caused by deposition of cystatin C amyloid fibrils in the walls of the brain arteries leading to single or or multiple strokes with fatal outcome. One or more affected members have been verified by histological examination in 8 families containing 127 affected. These originated from the same geographi

We investigate German–Russian bilingual children's sensitivity to formal and semantic cues when assigning gender to nouns in German. Across languages, young children have been shown to primarily rely on phonological cues, whereas sensitivity to semantic and syntactic cues increases with age. With its semi-transparent gender assignment system, where both formal and semantic cues are psycho linguist

The United Nations Security Council has the authority to adopt binding decisions and to authorise military means to ensure international peace and security. Whereas the Security Council is not typically associated with animal protection, wildlife issues have become an international security concern. Wildlife poaching and trafficking of wildlife products finance criminal networks and armed groups.

The past three decades have seen a surge in access to information (ATI) legislation at the global level. The right to freely review government information has become a component of political liberalization movements in countries transitioning to democracy as well as reform efforts in already established democracies. ATI is seen as an important measure in fighting corruption and promoting transpare

Abstract in UkraineІнтелігенція привласнює собі право говорити від імені всієї нації та екстраполювати на неї власні смаки, цінності й вподобання. Тому голоси інтелігенції багато в чому були визначальними в дискусіях про українську національну ідентичність, які набули імпульсу в пострадянському українському суспільстві. Історичний і культурний міський ландшафт Львова є особливо придатним місцем длIntelligentsia assumes the right to speak in the name of the entire nation and to extrapolate its own tastes, values and choices to it. Therefore, intelligentsia’s voices have been in many ways decisive in the discussions about Ukrainian national identity, which gained momentum in the post-Soviet Ukrainian society. The historical and cultural cityscape of L’viv is an especially apt site for invest