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Abstract in UndeterminedAlthough the diffusion of fertility behavior between different social strata in historical communities has received considerable attention in recent studies, the relationship between the diffusion of fertility behavior and the diffusion of people (migration) during the nineteenth century remains largely underexplored. Evidence from population registers compiled in the Histo
Ovarian cancer has one of the poorest prognoses among carcinomas. Advanced ovarian cancer often develops ascites and peritoneal dissemination, which is one of the poor prognostic factors. From the perspective of the “seed and soil” hypothesis, the intra-abdominal environment is like the soil for the growth of ovarian cancer (OvCa) and mesothelial cells (MCs) line the top layer of this soil. In rec
This open issue is published against the background of a major global pandemic. The old ‘normal’ seems far away and undesirable, as a socio-ecological transformation becomes even more urgent. The contributions featured here scrutinize the current trends in the capitalist mode of production and envision the alternative organization of our societies. They examine new configurations of work, to which
Complex diseases represent a number of common disorders such as allergic conditions, cardiovascular, metabolic and chronic inflammatory diseases. These diseases are caused by a combination of genetic, environmental and lifestyle factors. This complex etiology creates challenges when it comes to diagnostics, follow-up programs and treatment. Although exact disease mechanisms are yet to be elucidate
In the past, the identification of myocardial fibrosis was only possible through invasive histologic assessment. Although endomyocardial biopsy remains the gold standard, recent advances in cardiac imaging techniques have enabled non-invasive tissue characterization of the myocardium, which has also provided valuable insights into specific disease processes. The diagnostic accuracy, incremental yi
The alarmone nucleotide (p)ppGpp is a key regulator of bacterial metabolism, growth, stress tolerance and virulence, making (p)ppGpp-mediated signaling a promising target for development of antibacterials. Although ppGpp itself is an activator of the ribosome-associated ppGpp synthetase RelA, several ppGpp mimics have been developed as RelA inhibitors. However promising, the currently available pp
The unsurpassed versatility of heat sensitive biosensors is illustrated by various new applications of the flow-calorimetric biosensor system, the enzyme thermistor (ET) developed in our laboratory. The ET measures the reaction heat in a small column containing immobilized biocatalyst. Since most biological reactions are exothermic, the ET has a very broad applicability and numerous assays of clin
We examine socioecological drivers of nutrient overloading and eutrophication in the Chesapeake Bay associated with poultry production on the Delmarva Peninsula. We use a social metabolic analysis—rooted in a political-economy perspective—that highlights the interchange of matter and energy and the inextricable links within and between social and ecological systems, illuminating the social structu
What is the relation between scientific explanation and understanding? The thesis investigates a notion of understanding that is believed to be central to scientific explanation. The role of understanding in explanation is double: it is both an essential component, as well as a criterion, by which we select bona fide explanations from non-explanations. The model of explanation that is outlined in
This review with 239 references has as its aim to give the reader an introduction to the kinds of methods used for developing microchip based electrode systems as well as to cover the existing literature on electroanalytical systems where microchips play a crucial role for “none-destructive” measurements of processes related to living cells, i.e., systems without lysing the cells. The focus is on
During recent decades we have witnessed growing scientific concern, public debate and media attention concerning the possible adverse effects on humans and wildlife that may result from exposure to a wide range of environmental contaminants. These contaminants are called endocrine disrupters, or endocrine-disrupting compounds (EDCs) and are defined as chemicals that interfere with the function of
In this paper, we study the problems of estimating relative pose between two cameras in the presence of radial distortion. Specifically, we consider minimal problems where one of the cameras has no or known radial distortion. There are three useful cases for this setup with a single unknown distortion: (i) fundamental matrix estimation where the two cameras are uncalibrated, (ii) essential matrix
We propose a new model that accounts for the asymmetric response of volatility to positive (`good news') and negative (`bad news') shocks in economic time series – the so-called leverage effect. In the past, asymmetric powers of errors in the conditionally heteroskedastic models have been used to capture this effect. Our model is using the gamma difference representation of the generalized Laplace
The studies on political parties in the political sphere have for a long time been at the center of understanding why political parties act the way they do and how this affects their chances in upcoming elections. Instead, this paper aims to examine how representatives from the Social Democrats, Swedish Democrats and Liberals relate to the parties common positions regarding the European Union in t
AI och algoritmer förutspås revolutionera stora delar av samhället. Den snabba tekniska utvecklingen har redan idag nått arbetslivet och används i allt större utsträckning av arbetsgivare för att rekrytera personal, utöva arbetsledning och fatta viktiga arbetsrelaterade beslut. I gig-ekonomin och plattformsföretagen är användningen särskilt utbredd och algoritmer används för allt från att administAI and algorithms are predicted to revolutionize large sections of society. The rapid technical development has already reached working life and is increasingly used by employers to recruit staff, exercise management and make important work-related decisions. In the gig economy and platform companies the use is particularly widespread and algorithms are used for purposes ranging from managing the
