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Calcium binding to carbohydrate binding module CBM4-2 of xylanase 10A (Xyn10A) from Rhodothermus marinus was explored using calorimetry, NMR, fluorescence, and absorbance spectroscopy. CBM4-2 binds two calcium ions, one with moderate affinity and one with extremely high affinity. The moderate-affinity site has an association constant of (1.3 +/- 0.3) x 10(5) M(-1) and a binding enthalpy DeltaH(a)

Developing countries, including Egypt and North African countries, need to improve their quality of research by enhancing international cooperation and exchanges of scientific information, as well as competing for obtaining international funds to support research activities. Research must comply with laws and other requirements for research that involves human subjects. The purpose of this article

In recent years, a number of new developments in targeted therapies using radiolabeled compounds have emerged. New developments and insights in radioiodine treatment of thyroid cancer, treatment of lymphoma and solid tumors with radiolabeled monoclonal antibodies (mAbs), the developments in the application of radiolabeled small receptor-specific molecules such as meta-iodobenzylguanidine and pepti

It is generally considered mammals and birds have five Tec family kinases (TFKs): Btk, Bmx (also known as Etk), Itk, Tec, and Txk (also known as Rlk). Here, we discuss the domains and their functions and regulation in TFKs. Over the last few years, a large number of genomes from various phyla have been sequenced making it possible to study evolutionary relationships at the molecular and sequence l

Digital twins – realistic digital representations of physical entities, connected by real-time data flow – have spread into varied sectors of society. One sector that deserves further attention is the digital twinning of urban areas. The quick deployment of digital twins of cities and their interactions with the material and social elements of the 'smart city' have been enabled by discourses of te

Learning by teaching someone else has proven to be beneficial in both human-human and human-agent interaction. Instructing someone else, that is, taking the role as a tutor, has a series of positive effects on students' learning and performance. For example, the fact that someone else is in need of help seems to affect students to put more effort into the task at hand, trying harder, being more th

Since the Rio+20 gathering in 2012, and under the banner of blue growth, heads of state, corporations, investors and environmental NGOs have been debating the oceans’ role in solving everything from world food security, to provisioning of energy and natural resources, to mitigating the impacts of climate change and ensuring improved medical care. For the ocean and its resources to play this role,

The chapter provides a historic overview of the research in physics and chemistry for the development of radionuclides, radiopharmaceuticals, and instrumentation which have had a major impact for the today’s status of nuclear medicine. During the first half of the 20th century in particular, a number of researchers with relevance to the development of nuclear medicine have been awarded the Nobel P

Health system resilience, known as the ability for health systems to absorb, adapt or transform to maintain essential functions when stressed or shocked, has quickly gained popularity following shocks like COVID-19. The concept is relatively new in health policy and systems research and the existing research remains mostly theoretical. Research to date has viewed resilience as an outcome that can

Sweden needs affordable housing solutions to counteract segregation and isolation whilst promoting resilient cities. The COVID-19 pandemic has changed the conditions for being and sharing with others. The aim of the article is to explore residents practices of inhabiting, sharing and being involved in existing collaborative housing during the pandemic. The article conceptualizes collaborative hous

När skottskogsbruket/stubbskottsängsbruket upphörde i början av 1800-talet försvann även landskapet som humlesugan, Betonica officinalis L., var anpassad till. Från att ha varit allmän på sydvästra Lolland och i västra Mellanskåne blev den mycket sällsynt inom dessa kärnområden i humlesugans tidigare utbred- ning i Skandinavien. Ändå lyckades den överleva på sju lokaler. För att bevara dessa krävsWhen coppice forestry and the use of wooded meadows ceased in the early 19th century, the landscape to which Betony, Betonica officinalis L., was adapted also disappeared. From being common in southwestern Lolland and in western Mid­Skåne, it became very rare in these core areas of Betony’s earlier distribution in Scandi­ navia. However, the species has managed to survive at seven localities and t

Given a sensor network, TDOA self-calibration aims at simultaneously estimating the positions of receivers and transmitters, and transmitters time offsets. This can be formulated as a system of polynomial equations. Due to the elevated number of unknowns and the nonlinearity of the problem, obtaining an accurate solution efficiently is nontrivial. Previous work has shown that iterative algorithms

Berlin is a major tourist destination, a world city with a dramatic history. Many shelf meters have been written about it, not least combinations of travel guide and history book. The latest contribution of this kind is John Kampfner’s in Search of Berlin: The Story of a Reinvented City (London: Atlantic Books 2023, 400 pages). Kampfner is a British author, journalist and documentary maker with a

This literature review presents a summary of recent research about PM-less machines for electrical vehicles. Recently, IPM machines has proven to be very popular among electrical vehicle manufacturers. However, the neodymium permanent magnets being used are expensive and have a risk of rocketing the production cost of a machine if the price increases more. With this in mind, five PM-less machine t

High-frequency in situ measurements at Gosan (Jeju Island, Korea) during November 2007 to December 2008 have been combined with interspecies correlation analysis to estimate national emissions of halogenated compounds (HCs) in East Asia, including the chlorofluorocarbons (CFCs), halons, hydrochlorofluorocarbons (HCFCs), hydrofluorocarbons (HFCs), perfluorocarbons (PFCs), sulfur hexafluoride (SF6),

Tomographic surface X-ray diffraction (TSXRD) is an adaptation of classic surface X-ray diffraction to allow for measurements of polycrystalline surfaces. Compared to most other surface-sensitive techniques, surface X-ray diffraction has advantages in operando studies, since it can provide crystallographic information about surface structures in high gas pressures (above atmospheric) as well as th