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The G protein-coupled receptor GPR30 signalosome - A novel G protein-independent mechanism regulating cAMP signaling and receptor trafficking

Popular Abstract in Swedish Den här avhandlingen handlar om ett protein, en receptor, kallad GPR30. GPR30 tillhör proteinfamiljen G protein-kopplade receptorer vilka är nödvändiga för att celler ska kunna kommunicera med varandra och med sin omgivning. Förenklat sätt kan de ses sitta på ytan av en cell där de väntar på att någonting ska binda till dem, vilket aktiverar receptorerna och får dem attThe large protein family called G Protein-coupled receptors (GPCRs) has co-evolved with life throughout evolution; from single cell organisms all the way to complex beings such as us humans. The fact that GPCRs are involved in essentially every physiological event, and that ~50% of drugs on the current market are either directly or indirectly targeted towards the function of GPCRs, we can be certa

The role of the recording studio

The transformation from analogue to digital recording techniques has not only changed the ways of working for the studiotechnician, but affects the musician in the way he thinks about performance and sound, and therefore also his actual performance. The signal processing and the staging of the singing voice in the studio is both influenced by, and influences the estethics of popular song performa

A GPS-Based Methodology to Analyze Environment-Health Associations at the Trip Level : Case-Crossover Analyses of Built Environments and Walking

Environmental health studies have examined associations between context and health with individuals as statistical units. However, investigators have been unable to investigate momentary exposures, and such studies are often vulnerable to confounding from, for example, individual-level preferences. We present a Global Positioning System (GPS)-based methodology for segmenting individuals' observati

Bats may eat diurnal flies that rest on wind turbines

Bats are currently killed in large numbers at wind turbines worldwide, but the ultimate reason why this happens remains poorly understood. One hypothesis is that bats visit wind turbines to feed on insects exposed at the turbine towers. We used single molecule next generation DNA sequencing to identify stomach contents of 18 bats of four species (Pipistrellus pygmaeus, Nyctalus noctula, Eptesicus

The Revival Church

Throughout the years, the church has played an integral role in the community. It has served as a spiritual hub, a political symbol, and a center point for the community. One thing that cannot be denied is that the church has had some sort of power and influence on the community throughout different periods of time. You may even argue if the impact it has had on the community is positive or not. S

Icke-erkännande av transpersoner - En queerteoretisk analys av åsiktsfriheten i klassrummet

Diskrimineringsskydd för personer med könsöverskridande identitet eller uttryck infördes i svensk lagstiftning år 2009, många år efter att andra utsatta grupper erhöll ett likvärdigt skydd. Det sena införandet speglar en samhällelig diskurs som råder än idag, där vissa förhåller sig kritiska till användandet av transpersoners önskade pronomen. Frågan om transpersoners rättsliga skydd aktualiserasProtection from discrimination for people with transgender identity and expression was not introduced in Swedish legislation until 2009, years after other vulnerable groups obtained the same protection. The late introduction reflects a societal discourse that still prevails today, where some are critical of the use of transpeople’s desired pronouns. The issue of the legal protection of people wit

Metrics of making knowledge in a wilder Anthropocene : the roles and implications of produced knowledge in the governance of synthetic biology for biodiversity conservation

Under the growing influence of dominant discourses such as ecological modernisation and neo- liberalisation, proposed alternative conservation approaches focus more and more on efficiency. In the realm of biodiversity conservation, synthetic biology - the application of engineering to facilitate and accelerate the design or modification of genetic materials in living organisms – has emerged as an

Gröna Handlingar - Dynamiskt bevarande av organiskt material

Genbanker har existerat i en eller annan form i årtusenden. De tjänar som bevaring för biologiskt material. Formerna genbanker kan ta skiftar; De kan vara en botanisk trädgård, ett akvarium, eller ett laboratorie med frysarna fulla av genetiskt material. Ibland kan det röra sig om vävnadsprover, frön, eller DNA, Avsikten är att bevara, även om anledningarna kan vara olika. Det finns många likheterGene banks have in one form or another existed for thousands of years. They serve the purpose of repository for biological material. They can take the shape of a botanical garden, of an aquarium, or as a laboratory where the freezers are stuffed full with genetic resources. Sometimes as tissue samples or seeds, and sometimes as strands of DNA. The intention is to preserve, although the reasons may

How to manage the recession

In knowledge based industries, how has the changing economic climate in the United States altered hiring and training programs? Technology related jobs have faced a shortage of educated workers in the past and this trend was expected to continue in the future (See Waiting for Superman). With this situation in mind, has this sector followed the stereotype of the recession by laying off workers and

Food Waste in Everyday Life --The Power Relationship between People and Food Waste

Domestic food waste is a concept that recently has gained a lot of interest in the waste management industry. While people’s daily practices have converged more cultural and social symbols with food waste and keep re-defining and re-constructing the domestic food waste system, food waste then has emerged as a way to explain the real meaning hidden behind the everyday practices. By studying litera

A qualitative and quantitative analysis of the risk parameter LGD based on the Basel II Framework

Title: A qualitative and quantitative analysis of the risk parameter LGD based on the Basel II Framework Seminar date: 27 January 2007 Course: Financial Economy, Master Thesis, 10 poäng (15 ECTS) Author: Helén Dybing Advisor: Hans Byström Key words: LGD, LTV, Risk, Basel II, Estimation model Purpose: The purpose of this thesis is to get a deeper understanding of the risk parameter LGD and try to i

Laser trabeculoplasty in newly diagnosed multi-treated glaucoma patients

PURPOSE: To evaluate the intraocular pressure (IOP)-lowering effect of laser trabeculoplasty (LTP) in eyes which IOP had been substantially reduced by intensive topical treatment for one week.METHODS: Patients with newly diagnosed open-angle glaucoma were randomized to treatment with three IOP-lowering substances. One week later, 360° argon or selective LTP was performed. IOP was measured before L

Trajectories of primary health care utilization : a 10-year follow-up after the Swedish Patient Choice Reform of primary health care

Background: In January 2010, the choice reform was instituted in Swedish primary health care establishing free entry for private primary health care providers and enabling patients to choose freely among primary health care centers. The motivation behind the reform was to improve access to primary care and responsiveness to patient expectations. Reform effects on health care utilization have previ

Risk of Rehospitalization and Death in Patients Hospitalized Due to Asthma

Background: Asthma is a heterogeneous inflammatory airway disease that continues to cause considerable morbidity across the world, with poor asthma control leading to hospitalizations. Objective: The present study investigated the risk of rehospitalization, mortality, and the management of patients with asthma who had been hospitalized because of an asthma exacerbation. Methods: National Swedish h

Short-term outcomes following beyond total mesorectal excision and reconstruction using myocutaneous flaps : A retrospective cohort study

Introduction: Beyond total mesorectal excision (bTME) offers long-term survival in patients with advanced pelvic malignancy. At Skåne University Hospital (SUS) Malmö in Sweden, the vertical rectus abdominis musculocutaneous (VRAM) and gluteal maximus (GM) flap have been used for perineal reconstruction to promote healing and functional outcomes after significant tissue loss. This study aims to exa

Multagri outputsdec2015 final

Outputs&and&Proceedings&from&the&MULTAGRI&Research& Project& January&2014&–&December&2015& ! Contents' Page' Wie!können!Artenvielfalt!und!Landwirtschaft!besser!in!Einklang! gebracht!werden?!(DE)!! Report'to'Stakeholders'from'Lower'Saxony'Workshop' 1! Wie!können!Artenvielfalt!und!Landwirtschaft!besser!in!Einklang! gebracht!werden?!(DE)!! Report'to'Stakeholders'from'Saxony'and'Sweden'Workshops' 4! P

https://www.cec.lu.se/sites/cec.lu.se/files/multagri_outputsdec2015_final.pdf - 2026-05-05

Ghana afrint iii report

GHANA: AFRINT 3: Ghana Micro Report GHANA: Household–Level Farm–Nonfarm Linkages and Household Welfare Implications Fred M. Dzanku Institute of Statistical Social & Economic Research University of Ghana fdzanku@gmail.com & Daniel B. Sarpong Department of agricultural economics & Agribusiness University of Ghana akwei7@yahoo.com August 2014 AFRINT 3: Ghana Micro Report 1 Executive Summary This repo

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/ghana_afrint_iii_report.pdf - 2026-05-05

"Utan naturen kan vi inte leva" - Associationer, erfarenheter, värderingar och miljöengagemang hos unga utomeuropéer i Malmö

Caroline Arvaker Utan naturen kan vi inte leva I naturen finns alla våra resurser vilket gör den viktig att skydda. Detta är en gemensam värdering hos ett antal unga utomeuropéer boende i Malmö. Dock leder inte pro naturella värderingar alltid till ett miljöengagemang i handling, det finns andra faktorer som spelar in. I mitt masterarbete har jag genom intervjuer undersökt hur tio utomeuropéer ABSTRACT The purpose of this study is to examine how young adults with non-European background and with an upbringing in a city associate to nature and what may have influenced these associations. Given that a majority of people live in cities, there is a risk that many young people do not spend time in natural environments, which may affect their associations to nature and also their environment

Normskyddsläran i aktiebolagsrätten - om normskyddets påverkan på bolagsledningens skadeståndsansvar

Uppsatsen behandlar normskyddslärans påverkan på bolagsledningens aktiebolagsrättsliga skadeståndsansvar. Syftet är att på ett kritiskt sätt utreda hur normskyddsläran påverkar bolagsledningens skadeståndsansvar. De frågeställningar som uppsatsen utgår från är vidare: Hur påverkar normskyddsläran skadeståndsansvaret för bolagsledningen? Vilka effekter kan de argument som framfördes av HD inom rameThe thesis deals with the impact the doctrine of norm protection has on a company management’s liability to pay damages. The purpose is to critically examine how the doctrine affects a company management’s liability to pay damages. The thesis is furthermore based on the following questions: How does the doctrine of norm protection affect a company management’s liability to pay damages? What effect

Oligopolföretags parallella uppträdanden som bevismedel för ett samordnat förfarande - Företagens intressen mot intresset av en fungerande inre marknad

Uppsatsen behandlar svårigheterna för oligopol att beakta varandras beteenden, då detta kan anses utgöra ett samordnat förfarande. Att på ett självständigt och intelligent sätt anpassa sig till andra företags beteenden är något helt tillåtet i konkurrensrätten, och begränsas inte av EU-rättens artikel 101.1 i fördraget om Europeiska unionens funktionssätt. Problematiken uppstår om kommissionen stöThis essay examines the fine line between parallel behaviour of companies active in an oligopolistic market and concerted practices. Enterprises are fully permitted to independently and intelligently adapt their behaviour to the actions of their competitors, since this conduct is not illegal according to article 101.1 in the Treaty on the Functioning of the European Union. However, the Commission