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Bröstcancer är av stor relevans i dagens samhälle på grund av dess höga frekvens och mortalitetsgrad. Behandling är härjämte individualiserad utifrån tumörtyp och uttryck av hormonreceptorer. Med upptäckten av en ny receptor, GPR30, som svarar på östrogen, har forskning drivits kring hur denna samverkar med hypoxi, hur det bidrar till tumörcellernas överlevnad samt dess prognostiska och prediktiv

Evolutionen som livboj för en krympande slända Många organismer påverkas negativt av mänsklig miljöpåverkan, och riskerar att dö ut. Evolutionära processer kan dock fungera som en livboj och bromsa den negativa utvecklingen från miljöförändringar. Global uppvärmning driver en insektsart till en mindre kroppsstorlek. Men när naturlig selektion istället verkar för en stor kroppsstorlek kommer de ne

This article sets out to study the ways in which reactions and adaptations to modernity and societal change among non-elite communities in late nineteenth-century Sweden are visible in contemporary attitudes to social deviants and nonconformists. In Swedish provincial cultures, narratives about local characters in the oral tradition played a significant part in regional identity formation in the n

This thesis investigates particle sorting in deterministic lateral displacement (DLD) microfluidic devices, with a focus on how particle size and shape influence sorting behavior. A broad range of synthetic and biological particles were studied, including polystyrene particles, fabricated silicon-based structures, and bacterial samples with diverse physical properties.While DLD has traditionally b

Selective depletion of nerve growth factor receptor-bearing neurons in the basal forebrain cholinergic system nuclei by the immunotoxin 192 IgG-saporin offers a new and highly useful tool for the study of the role of the forebrain cholinergic system in cognitive functions. In the present study, we have tested the effects of 192 IpG-saporin in an operant delayed matching-to-position task which has

BACKGROUND: Mounting evidence supports a significant role of inflammation in Parkinson's disease (PD) pathophysiology, with several inflammatory pathways being suggested as playing a role in the dopaminergic degeneration seen in humans and animal models of the disease. These include tumor necrosis factor, prostaglandins and oxidative-related stress components. However, the role of innate immunity

Purpose: The aim of this paper is to explore the causes of variations in financial accounting and disclosure practices in a municipal setting highly influenced by governance reforms - the Swedish municipal waste management sector. This focus is motivated by the claim that recent governance reforms have made the organization of public services delivery more diversified and fragmented, which may hav

Plastics have become ubiquitous in modern society. It is a group of materials that is versatile and useful in many types of applications and have thus become extremely popular. Plastics are thus important for many industries and value chains as well as for everyday practices of most individuals – and should thus be also for investors and financial actors. A transition to sustainable plastics will

Tactile feedback plays a vital role in inducing ownership and improving motor control of prosthetic hands. However, commercially available prosthetic hands typically do not provide tactile feedback and because of that the prosthetic user must rely on visual input to adjust the grip. The classical rubber hand illusion (RHI) where a brush is stroking the rubber hand, and the user's hidden hand synch

Silicon (Si) phases such as biogenic silica, lithogenic silicate and authigenic silica/silicate in marine sediments provide valuable information about past Si cycling. Wet-chemical sequential leaching methods are often applied to extract different Si phases from marine sediments to study Si diagenetic processes in shallow subsurface. The potential of this method to separate Si phases from deeply-b