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A burden of rare copy number variants in obsessive-compulsive disorder
Right ventricular dyssynchrony predicts outcome in pulmonary arterial hypertension when assessed in multiple cardiac magnetic resonance views
“Otiosorum hominum receptacula”: Orthodox Religious Houses in Ingria, 1615–52
The essay collects and analyses sources on the Russian Orthodox monasteries of the Swedish province of Ingria (Ingermanland). These houses have rarely been treated; their very existence is largely unknown among specialists, although they are the only Orthodox religious houses to have existed in Scandinavia before the mid-20th century, apart from those of post-1809 Finland. On the basis of printe
Synthesis and tentative identification of novel polybrominated diphenyl ether metabolites in human blood
Hydroxylated polybrominated diphenyl ethers (OH-PDBEs) are exogenous, bioactive compounds that originate, to a large extent, from anthropogenic activities, although they are also naturally produced in the environment. In the present study nine new authentic OH-PBDE reference standards and their corresponding methyl ether derivatives (MeO-PBDEs) were synthesised and characterised by NMR spectroscop
A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile
Milk and dairy products - a scoping review for nordic nutrition recommendations 2023
Introduction: Milk and dairy products are major sources of protein, calcium, and other micronutrients. Milk and dairy products contribute with approximately half of the total intake of saturated fat. Saturated fat is an important determinant of plasma total and low density lipoprotein (LDL)-cholesterol levels, and a causal relationship between high LDL-cholesterol and atherosclerotic cardiovascula
Efficacy of immune checkpoint inhibitors in alveolar soft-part sarcoma : results from a retrospective worldwide registry
Background: Conventional cytotoxic drugs are not effective in alveolar soft-part sarcoma (ASPS). Immune checkpoint (programmed cell death protein 1/programmed death-ligand 1) inhibitors (ICIs) are promising drugs in ASPS. A worldwide registry explored the efficacy of ICI in ASPS. Materials and methods: Data from adult patients diagnosed with ASPS and treated with ICI for advanced disease in expert
Clinical impact of medication reviews for community-dwelling patients in primary healthcare
Time-resolved transmission spectroscopy of the ultra-hot Jupiter WASP-189 b
Ultra-hot Jupiters are tidally locked with their host stars, dividing their atmospheres into a hot dayside and a colder nightside. As the planet moves through transit, different regions of the atmosphere rotate into view, revealing different chemical regimes. Highresolution spectrographs can observe asymmetries and velocity shifts and offer the possibility for time-resolved spectroscopy. The ultra
Accumulation of advanced glycation end products in skin and increased vascular ageing in the general population : The Malmö Offspring Study
Making hot Jupiters in stellar clusters - II. Efficient formation in binary systems
Observations suggested that the occurrence rate of hot Jupiters (HJs) in open clusters is largely consistent with the field (∼ 1 per cent) but in the binary-rich cluster M67, the rate is ∼ 5 per cent. How does the cluster environment boost HJ formation via the high-eccentricity tidal migration initiated by the extreme-amplitude von Zeipel–Lidov–Kozai (XZKL) mechanism forced by a companion star? Ou
Evaluation of the adsorptive behaviour of kraft black liquor on nanofiltration model membrane surfaces via quartz crystal microbalance with dissipation monitoring (QCM-D)
Clinical and Metabolic Signatures of FAM47E–SHROOM3 Haplotypes in a General Population Sample
Introduction: Genome-wide association studies (GWAS) identified a locus on chromosome 4q21.1, spanning the Family With Sequence Similarity 47 Member E (FAM47E), Starch Binding Domain 1 (STBD1), Coiled-Coil Domain Containing 158 (CCDC158), and Shroom Family Member 3 (SHROOM3) genes, to be associated with kidney function markers. Functional studies implicated SHROOM3 as the effector gene, demonstrat
Limosilactobacillus reuteri DSM 17938 Produce Bioactive Components during Formulation in Sucrose
Improved efficacy of probiotics can be achieved by using different strategies, including the optimization of production parameters. The impact of fermentation parameters on bacterial physiology is a frequently investigated topic, but what happens during the formulation, i.e., the step where the lyoprotectants are added prior to freeze-drying, is less studied. In addition to this, the focus of proc
