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The tau R406W mutation causes progressive presenile dementia with bitemporal atrophy

Frontotemporal dementia (FTD) and Alzheimer's disease (AD) are two frequent causes of dementia that share both clinical and neuropathological features. Common to both disorders are the neurofibrillary tangles consisting of aggregations of hyperphosphorylated tau protein. Recently, a number of different pathogenic mutations in the tau gene have been identified in families with FTD and parkinsonism

Bullied into it: bullying, power and the conduct of conduct

Bullied into it: Bullying, Power and the Conduct of Conduct takes issue with the way in which the relations between school bullying and power have commonly been understood. Drawing on long-term ethnographic fieldwork conducted in two schools in the northern Vietnamese port city of Haiphong, the book contextually situates the bullying that occurs within the disciplinary framework of the school an

Microvariation in Norwegian long distance binding

It is well known that (some speakers of) Norwegian allow long distance binding, defined here as binding across a finite clause boundary. A number of factors that facilitate long distance binding have also been identified. In the study reported on here, 93 native speakers of Norwegian judged 30 sentences in a web-based questionnaire. The results show that V2 order in the embedded clause reduces the

Phosphatised olenid trilobites and associated fauna from the Upper Cambrian of Vastergotland, Sweden

Secondarily phosphatised olenid trilobites from organic-rich limestones (orsten) in the Furongian (Upper Cambrian) of Vastergotland, south-central Sweden, are described and illustrated. All trilobites originate from the Peltura scarabaeoides Zone and were collected on the western slope of Kinnekulle. Only the dorsal exoskeletons have become secondarily phosphatised, and the ventral appendages are

Arthritis induced in rats with non-immunogenic adjuvants as models for rheumatoid arthritis

Rat models are useful for studies of the pathogenesis of rheumatoid arthritis (RA) since rats are extraordinarily sensitive to induction of arthritis with adjuvants. Injection of not only the classical complete Freund's adjuvant but also mineral oil without mycobacteria and pure adjuvants such as pristane and squalene, induce severe arthritis in many rat strains. Models like pristane-induced arthr

The Substituted Judgment Standard. Studies on the Ethics of Surrogate Decision Making

Popular Abstract in Swedish Beslutsinkompetenta patienter behöver en ställföreträdande beslutsfattare som kan fatta vårdbeslut för deras räkning. En av de etiska frågor som aktualiseras i detta sammanhang är vilka riktlinjer som bör gälla för sådant beslutsfattande. Enligt ?the Substituted Judgment Standard? (SJS) bör en ställföreträdare fatta det beslut som patienten själv hade fattat, om denne hPatients who are incompetent need a surrogate decision maker to make treatment decisons on their behalf. One of the main ethical questions that arise in this context is what standard ought to govern such decision making. According to the Substituted Judgment Standard (SJS), a surrogate ought to make the decision that the patient would have made, had he or she been competent. Although this standard

Analysis of Mice Lacking the Heparin-Binding Splice Isoform of Platelet-Derived Growth Factor A

Platelet-derived growth factor A-chain (PDGF-A) exists in two evolutionarily conserved isoforms, PDGF-Along and PDGF-Ashort, generated by alternative RNA splicing. They differ by the presence (in PDGF-Along) or absence (in PDGF-Ashort) of a carboxyterminal heparin/heparan sulfate proteoglycan-binding motif. In mice, similar motifs present in other members of the PDGF and vascular endothelial growt

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English (French summary below)Is it still possible to speak of authority other than in negative terms? In particular, to speak of exercising authority in religious institutions? I believe so. It is essential to exercise authority, also in religious institutions. But this exercise is not a simple matter. I propose to reflect on the question from four perspectives. The first is inspired by Martin Lu

Prion-like seeding and nucleation of intracellular amyloid-β

Alzheimer's disease (AD) brain tissue can act as a seed to accelerate aggregation of amyloid-β (Aβ) into plaques in AD transgenic mice. Aβ seeds have been hypothesized to accelerate plaque formation in a prion-like manner of templated seeding and intercellular propagation. However, the structure(s) and location(s) of the Aβ seeds remain unknown. Moreover, in contrast to tau and α-synuclein, an in

What Now for Myanmar? - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law

What Now for Myanmar? - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of Programme Work Met

https://rwi.lu.se/2015/12/21/what-now-for-myanmar/ - 2026-06-05

InfraVis@LU

InfraVis is a Swedish national Research Infrastructure for data visualization. InfraVis helps you visualize research data from any scientific domain and gives you access to state-of-the-art visualization competence, support, equipment, training, and methods. InfraVis@LU is the InfraVis node for Visualisation and Analysis at Lund University, coordinated by CIPA.   InfraVis provides advanced visuali

https://www.microscopy.lu.se/cipa/infravislu - 2026-06-05