Filetype
Autoignition in SI engines is an abnormal combustion mode and may lead to engine knock which is an undesired phenomenon in SI engines. It may cause damage and it is a source of noise in engines. Knock limits the compression ratio of the engine and a low compression ratio means low fuel conversion efficiency of the engine. This thesis presents a theoretical investigation about the modeling of the e
Embryonic stem cells (ESCs) are derived from the inner cell mass (ICM) of blastocyst stage embryos, and upon differentiation into embryoid bodies (EBs) they recapitulate the genetic, cellular and morphological events occurring in early embryogenesis. Among several signalling pathways and inductive factors, the fibroblast growth factors (FGFs) and their receptors (FGFRs) have been shown to be impor
Popular Abstract in Swedish Varje år insjuknar mer än 8000 kvinnor i Sverige i bröstcancer, och 5 år efter diagnos är nära 90% fortfarande i livet. Trots att prognosen för majoriteten av patienterna är god, dör 1400 kvinnor årligen av bröstcancer. Till följd av detta pågår mycket forskningsarbete för att finna faktorer som bättre kan förutsäga prognos, prognostiska studier, men även för att finna Breast cancer is the most common tumour form and the second leading cause of death in solid tumours in women in the Western world. Despite improvements in the treatment, a considerable number of patients will relapse and die from their breast cancer. At the same time, a substantial number of patients will be over-treated, as they would have been cured by surgery and radiotherapy alone. In the meta
Formation of incipient charnockite in Söndrum, SW Sweden and the Kerala Khondalite Belt (KKB), S. India is accompanied by zircon growth. The age of the dehydration event is constrained by dating newly formed zircon to 1397±4 Ma (2?, MSWD=1.7) in Söndrum and ca. 520-510 Ma in S. India by secondary ionization mass spectrometry (SIMS). The formation of incipient charnockites correlates with regional
The exposure to fragrances is widespread and contact allergy to fragrance substances affects 1–4% of the general population. Many fragrance substances are volatile and it can therefore be suspected that they may evaporate from petrolatum patch test preparations applied in test chambers. In the first two papers included in this thesis the aims were to i) to investigate the stability of fragrance pr
Popular Abstract in Swedish See attachment in related material
Relationships among allotetraploid marsh orchids collectively assignable to Dactylorhiza majalis s.l. are exceptionally complex because of multiple origins, secondary hybridization with each other, and with their parental lineages, local adaptation, and genomic reorganization processes, all extending through time and space. We sampled 34 populations from Britain and Ireland in an attempt to simult
Thermal-optical analysis is a conventional method for determining the carbonaceous aerosol fraction and for classifying it into organic carbon, OC, and elemental carbon, EC. Unfortunately, the different thermal evolution protocols in use can result in a wide elemental carbon-to-total carbon variation by up to a factor of five. In Europe, there is currently no standard procedure for determining the
The collections of fungus gnats by Johan Wilhelm Zetterstedt (1785-1874), lodged in the Museum of Zoology in Lund, Sweden, are examined for all species belonging in the tribe Exechiini Edwards. The majority of the material was collected in Fennoscandia, mainly in Sweden, in the first half of the 19(th) century. Altogether 37 species of the tribe Exechiini could be safely identified. Three addition
Popular Abstract in Swedish Årligen diagnostiseras cirka 60 000 nya fall av cancer i Sverige (Socialstyrelsen, 2015), och var tredje person beräknas få en cancerdiagnos under sin livstid. Trots stora framsteg inom forskning och utveckling är cancer, näst efter hjärt- och kärlsjukdomar, den vanligaste dödsorsaken i vårt samhälle. Bland de tio vanligaste formerna av cancer hör lymfom, vilket är et
Popular Abstract in Swedish Dagligen produceras hos en vuxen människa det helt otroliga antalet av 300 miljarder (300.000.000.000) blodkroppar. De flesta är röda blodkroppar som ansvarar för att transportera syre från lungorna till alla celler i kroppen samt koldioxid i andra riktningen. Vidare finns olika sorters vita blodkroppar som skyddar oss från infektioner samt blodplättar (eller trombocyteHematopoietic stem cells (HSCs) are responsible for the daily and life long production of large numbers of mature blood cells through highly regulated self-renewal and multilineage capabilities. Leukemias on the other hand, are characterized by a clonal, dysregulated, lineage skewed proliferation and impaired differentiation as the result of multiple accumulated genetic events. In acute myeloid le
Popular Abstract in Swedish Allt eftersom fler och fler organismers totala uppsättning gener, genomet, sekvenseras ökar fokus på att kartlägga de genprodukter, proteiner, som uttrycks. Att kunna studera de proteiner som uttrycks mer eller mindre vid olika tidpunkter eller cellulära tillstånd utgör en viktig del i sökandet efter kunskap om biologiska och medicinska processer. Studier av den totala The study of the protein complement of a genome is called proteomics. Proteomics can be defined as identification, quantification and characterization of a total set of proteins expressed at different time-points or under different cellular states to provide global information about biological processes. The study of membrane proteins is a challenging area in the development of proteomic research.
Popular Abstract in Swedish Högt blodtryck, hypertoni, är en folksjukdom som ökar risken att insjukna i slaganfall och hjärtinfarkt. I flertalet fall är orsaken till hypertoni okänd och man talar då om primär hypertoni. Mellan 30 och 60% av blodtrycksvariationen i befolkningen bestäms av genetiska faktorer medan resten beror på omgivningsfaktorer. Primär hypertoni uppkommer sannolikt på grund av sGenetic factors are of importance for the development of primary hypertension (HT). Intrauterine growth retardation, salt sensitivity and insulin resistance are all characteristic features of individuals prone to develop HT. Monogenic forms of hypertension such as Liddle´s syndrome (LS) and Apparent Mineralocorticoid Excess (AME), and hypotension such as Gitelman´s syndrome (GIT) have recently bee
Popular Abstract in Swedish Bröstcancer är den vanligaste cancerformen hos västerländska kvinnor. I Sverige kommer var tionde kvinna att drabbas av bröstcancer, vilket motsvarar drygt 5000 kvinnor om året. Dödligheten i bröstcancer är 30%. Detta innebär att en tredjedel av de som drabbas kommer att dö av sin sjukdom. Det är dock inte själva tumören i bröstet som dödar eftersom denna i princip alltBreast cancer is one of the most common cancer forms in the industrialized world. Only in Sweden, nearly 6000 women are diagnosed with breast cancer each year and 1/3 of them eventually succumb to the disease. Wnts are a family of genes that have been implicated in many human tumours, so far mainly studied in colorectal cancer where activated Wnt signalling occurs in a vast majority of tumours. Wh
Popular Abstract in Swedish Bukspottkörteln (pankreas) består av en exocrin och en endocrin del. Den exocrina delen som studerats i denna avhandling innerhåller acinarceller som producerar bukspott innehållande matsmältningsenzymer. Dessa enzymer spjälkar proteiner, kolhydrater och fetter som finns i födan, till sina mindre beståndsdelar aminosyror, monosackarider och fettsyror. Efter sekretion av
