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Efficacy and cost-effectiveness of Stem Cell injections for symptomatic relief and strUctural improvement in people with Tibiofemoral knee OsteoaRthritis : Protocol for a randomised placebo-controlled trial (the SCUlpTOR trial)

Introduction Knee osteoarthritis (KOA) is a highly prevalent disabling joint disease. Intra-articular stem cell therapy is increasingly being used for treating KOA with little high-quality evidence to support its use. The aim of this study is to investigate the efficacy, safety and cost-effectiveness of allogeneic mesenchymal stem cells (Cymerus MSCs) for treating symptomatic tibiofemoral KOA and

Förhöjd vardaglighet : Unga på landsbygden gör vardag

I avhandlingen skildras vardagslivet hos en grupp unga som bor på landsbygden. Medan vardagen i regel ses som grå och trist visar avhandlingen hur unga gör den till något särskilt, meningsfullt och roligt, hur de gör förhöjd vardaglighet. Genom att studera ungas vardagsliv med etnografiska metoder och teoretisk nyfikenhet når studien kunskap bortom de problembeskrivningar som vanligtvis skildrar sToday, the terms ‘young people’ and ‘rural Sweden’ are automatically associated with problems. Young people are associated with various worrying issues, such as mental illness, stress, pressure at school, or internet risk. Being young and living in a rural community is often regarded as especially problematic. Rural life is thought dull, and bracketed with isolation, lack of meaningful activities,

Children with palliative care needs - the landscape of the nordic countries

BACKGROUND: To strengthen palliative care for children in the Nordic countries, an updated status of current needs, resources, clinical services, education, and research is necessary to align and consolidate future research. A Nordic research collaboration initiative for children with palliative care needs was assembled in 2023. Building on this initiative, this paper presents an overview of pedia

Burden of malignant mesothelioma in China during 1990-2019 and the projections through 2029

ObjectiveTo provide the most up-to-date data on the burden of malignant mesothelioma (MM) and the projections through 2029 in China.MethodsData on patients diagnosed with MM from China during 1990-2019 were obtained from the Global Burden of Disease (GBD) 2019 database, including annual cases and deaths data and age-standardized rates of incidence, mortality, and disability-adjusted life-years (DA

The ATLAS experiment at the CERN Large Hadron Collider: a description of the detector configuration for Run 3

The ATLAS detector is installed in its experimental cavern at Point 1 of the CERN Large Hadron Collider. During Run 2 of the LHC, a luminosity of ℒ = 2 × 1034 cm-2 s-1 was routinely achieved at the start of fills, twice the design luminosity. For Run 3, accelerator improvements, notably luminosity levelling, allow sustained running at an instantaneous luminosity of ℒ = 2 × 1034 cm-2 s-1, with an a

Evidence that CD36 is expressed on red blood cells and constitutes a novel blood group system of clinical importance

BACKGROUND AND OBJECTIVES: Polymorphic molecules expressed on the surface of certain blood cells are traditionally categorized as blood groups and human platelet or neutrophil antigens. CD36 is widely considered a platelet antigen (Nak a ) and anti-CD36 can cause foetal/neonatal alloimmune thrombocytopenia (FNAIT) in CD36-negative pregnant women. CD36 is used as a marker of differentiation in earl