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Epithelial to mesenchymal transition (EMT) is a critical event in cancer progression and is closely linked to the breast epithelial cancer stem cell phenotype. Given the close interaction between the vascular endothelium and cancer cells, especially at the invasive front, we asked whether endothelial cells might play a role in EMT. Using a 3D culture model we demonstrate that endothelial cells are
Popular Abstract in Swedish Mitralisklaffen (lat. valva mitralis; valva bicuspidalis) är den klaff i hjärtat som finns mellan vänster förmak och vänster kammare. Till utseendet liknar klaffen påvens huvudbonad, mitra, varifrån namnet härstämmar. Mitralisklaffen består av två segelliknande flikar (klaffblad) med en upphängningsapparat som fäster sig i vänster-kammarens vägg. När vänster kammare konNormalization of life expectancy after mitral valve surgery is highly dependent on early diagnosis and referral for surgical treatment. Among cases treated surgically, the majority (60–70%) have a degenerative etiology, which is also easiest to repair. The general aim of this thesis was to bring research on treatment of degenerative mitral regurgitation a step further in order to improve clinical
The remodeling phase of tissue repair in lung disorders such as idiopathic pulmonary disease, asthma, obliterative bronchiolitis, and after lung transplantation is not well understood. One of the key players in fibrosis is the fibroblast and its progenitor, the fibrocyte. The fibroblast is the main producer of extracellular matrix molecules such as collagen, versican, perlecan, biglycan, and decor
This thesis addresses what students describe as their reasons for attending university, their descriptions of their encounters with the university milieu, and what significance they believe the existence of a local university such as Halmstad in south-west Sweden may have had in this. The empirical basis of the study consists of interviews with 58 students taking one of three courses at Halmstad U
The aim of this thesis is to examine what implications microfinance may have for economic growth by exploring the linkages of microfinance, the financial system and economic growth. Due to the lack of previous studies explicitly linking microfinance to economic growth, the weight of the thesis falls on developing a theoretical framework where the different channels to economic growth can be discer
The aim of the study is to investigate how does the micro-credit does, small scale loans to poor people, work in poverty alleviation and building social capital in rural Bangladesh. The major objective of the study is to show how the NGO activities help to increase women's access to micro-finance, generate new income earning opportunities, and to enhance social mobilization and create formal n
Information is essential in order for pharmaceutical companies to be successful. This essay focuses on the information provision of pre-clinical scientists at AstraZeneca R&D Lund, and the role of the company library in this process. In semi-structured interviews, four pre-clinical scientists were asked to describe their information provision regarding what type of information they need, how t
Track switches are vital parts in the railway construction. They meet an important feature when planing and stearing the traffic flow through them to increase capacity. To ensure functionality during winter they have since the 50- century systematically installed switch heating with different technical solutions but with the same objective, to keep the moving parts on the switch free from snow and
