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Technical performance of a proximity extension assay inflammation biomarker panel with synovial fluid

The plasma proteome can provide a deeper understanding of the pathophysiology of different diseases and is a key source for detection of new biomarkers. Proximity extension assay (PEA), developed by Olink Proteomics (Uppsala, Sweden), detects proteins by using pairs of antibodies that are linked to oligonucleotides; upon target binding, the probes anneal when in proximity and the oligonucleotides

Migration as a Constitutional Crisis for the European Union

This chapter aims to offer insights into the wider implications for the rule of law, including for the EU constitutional order, of the restrictions of migrants’ and asylum-seeker’ rights that follow from systematic noncompliance with the Common European Asylum System (CEAS) by certain Member States. In other words, has the migration and asylum crisis developed into an EU constitutional crisis? The

Rethinking performance management

Many public sector managers and professionals perceive performance measurement as an administrative burden with limited benefits. Numbers are collected for other people's purposes. At worst, poorly incentivized indicators force managers and professionals to take actions that go against the overall objectives of the organization. Professionals in sectors such as healthcare, education and social ser

Which countries are prepared to green their coal-based steel industry with electricity? - Reviewing climate and energy policy as well as the implementation of renewable electricity

Global steel production is currently dependent on coal and capital-intensive production facilities with long economic lifetimes. While the Paris Agreement means carbon neutrality must be reached globally by 2050–2070, with negative emissions thereafter, coal-based steel production today accounts for around 8% of global energy-related CO2 emissions. Its production may stabilize or even decline in i

Genetics of diabetes - Are we missing the genes or the disease?

Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction, and failure of different organs, especially the eyes, kidneys, nerves, heart, and blood vessels. Several pathogenic processes are involved in the development of diabetes

The rise or demise of 'Social Europe' - A case law study in the context of worker protection

The European Union is facing several challenges of constitutional, democratic, political and social nature. One of these challenges is the EU’s ‘social deficit’. The European Commission has listened to the critique and committed itself to reorient the European integration project towards a ‘Social Europe’. The addition of social provisions to primary law through the Treaty of Lisbon, a promised re

Statelessness and the ability to receive a residence permit based on impediments to enforcement

Being stateless, roughly means being without a citizenship of any nation. This is the definition of being stateless in legal terms, called de jure statelessness. There is also statelessness that entails being without the efficient protection of one’s nation, called de facto statelessness. Two groups of stateless migrants that correspond to these definitions are Bidoons from Kuwait and Palestinians

Law over mind, and body? A study of the debate and aftermath of the abortion travels to Poland in 1965 and the case of a midwife invoking her conscience in 2017

This thesis orbits around the changes in the Swedish abortion laws during the last century, and the relation to religion. The aim is to make visible the values enshrined in the first abortion law, and those in the current abortion law, as the legislation made a volte-face in the 1970’s. Today, abortion is a right and the state is the duty-bearer. This construction collides with the conscience of r

Co-pretreatment of spruce and poplar for ethanol production - Effects of mixed feedstocks on pretreatment and enzymatic hydrolysis efficiency

Fossila bränslen är mycket viktiga för dagens samhälle och transportsektorn är nästan helt beroende av dem. Tyvärr påverkar de miljön negativt och bidrar till att växthusgasnivå ökar. Jordens medeltemperatur har ökat med 0.8°C sedan början av industrialiseringen. Den globala uppvärmningen är ett naturligt förlopp, men har under de senaste åren varit en stor del av människors bidrag. Idag har atmosOil is very important for today’s society and the transportation sector is almost completely dependent on this material. Unfortunately, it affects the level of greenhouse gases negatively which in turn contribute to global warming. Therefore, it is necessary to reduce greenhouse gas emissions, especially in the sectors that emit the most, as transportation sector. The European Parliament has decid

Är tolkningsläran rättvis? - Med fokus på försäkringsavtal

Syftet med denna uppsats är att systematisera tolkningsläran för försäkringsavtal. Detta för att undersöka om det går att tolka försäkringsavtal på ett enhetligt sätt samt vilka för- respektive nackdelar det kan finnas med en enhetlig tolkningslära. Vidare syftar uppsatsen till att utreda huruvida tolkningsläran är rättvis, under ett synsätt, att tolkningsläran är ett sätt att uppnå rättvisa. ToThe aim of this paper is to establish and implement a framework for the systematic interpretation of insurance contracts. Specifically, this paper will try and establish a uniform means of interpreting an insurance contract, and identify and assess the negative and positive aspects associated with the adoption of such a system. Furthermore, this paper looks to investigate whether or not the interp

The effect of predation risk on partial migration

Påverkar rovfisk mörtens migrationsbeteende? Migration är ett mycket vanligt fenomen i djurriket. Det är en ofta säsongsbunden händelse med syfte av att till exempel söka efter föda, parningstillfällen eller för att undkomma rovdjur eller någon annan riskfylld miljö. Ibland är det bara vissa individer i en population av migrerande djur som deltar. Detta kallas i litteraturen för partiell migratioPartial migration, defined as when only some individuals within a population migrate whereas others remain as year-round residents, is ubiquitous in the animal kingdom. However, the reasons why some, but not all individuals migrate are not fully understood. Results from multiple recent studies indicate that the propensity to migrate often is flexible and influenced by ecological factors such as fo

Allmänna Bestämmelser - ett avtalsrättsligt fuskbygge? Om Högsta domstolens tolkning av entreprenadavtalet

Framställningen syftar till att undersöka hur HD:s tolkning av kommersiella entreprenadavtal utvecklats. För att uppnå syftet utreds hur entreprenadavtal ska tolkas, hur praxis har utvecklats på området sedan år 2000 samt vilka konsekvenser utvecklingen kan medföra. Entreprenadavtal är inte lagreglerade i svensk rätt och sparsamt behandlade i doktrin. Termen kan förstås som ett avtal där entrepreThe purpose of the thesis is to examine how the interpretation of construction contracts has evolved by the Supreme Court. The thesis examines how the contracts should be interpreted, how the precedents have developed in the field since year 2000 and what consequences the development could bring. Construction contracts are not regulated by Swedish law and are rarely treated in the doctrine. A con

Plaståtervinningens roll i en hållbar industri - Det teknologiska innovationssystemet av återvunnen plast i Skåne

Det här examensarbetet har identifierat möjligheter och begränsningar för att främja en hållbar plaståtervinning i den skånska plastindustrin, på uppdrag av Region Skåne. Analysen har gjorts med hjälp av ramverket teknologiska innovationssystem (TIS), som syftar till att identifiera de systemsvagheter som kräver politiska åtgärder för att stärka TIS:ets prestanda. Aktörerna i den skånska plastindu

Neutrality 2.0: Redefining the Law of Neutrality in a Changing World - A Critical Analysis on the Validity and Relevance of the Law of Neutrality

The unprecedented military and economic support provided by non-participating States to Ukraine following the Russian aggression has reignited the debate surrounding the law of neutrality. The law of neutrality, first codified in the Hague Conventions of 1907, defines the legal relationship between States involved in an international armed conflict (IAC), known as belligerents, and States not taki

Coherent Interactions in Rare-Earth-Ion-Doped Crystals for Applications in Quantum Information Science

Popular Abstract in Swedish Den här avhandlingen handlar om hur kristaller, som innehåller en liten mängd av ämnen tillhörande gruppen sällsynta jordartsmetaller, kan användas för forskning och tillämpningar rörande kvantinformation. Genom att belysa kristallerna med laserljus kan atomernas tillstånd styras och studeras. I avhandlingen diskuteras olika aspekter av hur de sällsynta jordartsatomer sThis thesis describes investigations of the use of cryogenically cooled rare-earth-ion-doped crystals for quantum information processing and quantum optics. Several aspects of the coherent interaction between light and rare-earth ions in solids are addressed. Quantum information science has given physicists new views of quantum mechanics. The transmission of quantum states has already found pract

Development of the Packaging Material Process at Plastal AB Simrishamn

In the automotive industry, it is common that the customers provide the suppliers with the necessary packing material needed for delivery of the goods. The reason for this is that it makes the handling and unpacking of incoming goods at the customer easy, but it also makes sure that the quality of the packing material is high, and that the transportation damages of the goods are minimised. It shou