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Small populations are prone to inbreeding depression due to the increased likelihood of mating between close relatives, resulting in the expression of deleterious recessive mutations. While this increases the risk of population extinction, high levels of inbreeding can initiate a purging process, where natural selection gradually eliminates strongly deleterious mutations. This purging effect has b

The Re-Os (rhenium-osmium) chronometer applied to molybdenite (MoS2) is now demonstrated to be remarkably robust, surviving intense deformation and high-grade thermal metamorphism. Successful dating of molybdenite is dependent on proper preparation of the mineral separate and analysis of a critical quantity of molybdenite, unique to each sample, such that recognized spatial decoupling of 187Re par

Gross primary production (GPP) of the vegetation is the largest carbon exchange process of the global carbon cycle. Currently, within satellite-based remote sensing, GPP is generally modelled using linear light use efficiency models where GPP is related to photosynthetically active radiation absorbed by the green vegetation (APAR). These models work well on moderate to low spatiotemporal averaging

Introduction Major depressive disorder (MDD) is a major global healthcare challenge. This is, in part, due to the lack of treatment response and chronic course of MDD. Such a course of illness is often termed treatment-resistant depression (TRD) and is seen in over one-Third of people with MDD. Reasons for treatment resistance are not well established, nor is the definition of TRD. Duration and se

Background: Self-rated health (SRH) is an international measure and indicator of mortality and morbidity that can be used as a mortality predictor in adulthood. This study aimed to examine the status of SRH among adults in Qazvin Province and its relationship with physical activity levels and demographic factors in primary care centers. Methods: This is a cross-sectional study. We included data fr

Heart failure (HF) is a complex clinical syndrome characterized by exercise intolerance. However, most diagnostic assessments are performed at rest, when many patients are asymptomatic. To better understand the underlying pathophysiology, examination during exercise is needed. Hydraulic force, a newly identified mechanism of diastolic filling, is proportional to the difference in short-axis areas

Långvariga somatiska symtom som inte kan förklaras av somatisk patologi är vanliga inom primär- och specialistvård. Svårigheter med att kategorisera dessa tillstånd gör det svårt för patienter att hitta en effektiv behandling, bli validerade i sin upplevelse och att bli uppfattade som trovärdiga. Tidigare studier pekar på att symtomen uppstår i interaktionen mellan somatiska och psykiska processerPersistent somatic symptoms that cannot be explained by somatic pathology are common both in primary and specialist care. Challenges in categorizing these conditions create difficulties for patients in finding effective treatment, finding validation in their experience and being perceived as credible. Previous studies indicate that these symptoms develop in the interaction between somatic and psyc