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Comparative financing analysis and political economy of noncommunicable diseases

The pandemic of chronic non-communicable diseases (NCDs) poses substantial challenges to the health financing sustainability in high-income and low/middle income countries (LMICs). The aim of this review is to identify the bottle neck inefficiencies in NCDs attributable spending and propose sustainable health financing solutions. The World Health Organization (WHO) introduced the "best buy" concep

Soil Moisture Assimilation Improves Terrestrial Biosphere Model GPP Responses to Sub-Annual Drought at Continental Scale

Due to the substantial gross exchange fluxes with the atmosphere, the terrestrial carbon cycle plays a significant role in the global carbon budget. Drought commonly affects terrestrial carbon absorption negatively. Terrestrial biosphere models exhibit significant uncertainties in capturing the carbon flux response to drought, which have an impact on estimates of the global carbon budget. Through

Masters of the Imperial City: Ideological perspectives on the Byzantine emperors of Patria Konstantinoupoleos

The paper concerns itself with the expressions of ideology in the late 10th century text known as Patria Konstantinoupoleos, the Patria of Constantinople. More specifically, it aims to examine the ideological tendencies and patterns which can be identified regarding the Byzantine emperors, individually and collectively. It takes a critical stance towards parts of the research that has previously b

The Consequences of Negligence Claims in Arterial Surgery - An Analysis of Two Periods with an Increasing Use of Endovascular Treatment

OBJECTIVES: Patient treatment within the Swedish medical service system can claim negligence injuries to the malpractice insurance review board and request financial compensation. The aim of this paper was to analyse the consequences of a negligence claim after arterial surgery between two periods with increasing use of endovascular treatment.METHODS: This was a retrospective cohort study of the a

A mutation-independent approach for muscular dystrophy via upregulation of a modifier gene

Neuromuscular disorders are often caused by heterogeneous mutations in large, structurally complex genes. Targeting compensatory modifier genes could be beneficial to improve disease phenotypes. Here we report a mutation-independent strategy to upregulate the expression of a disease-modifying gene associated with congenital muscular dystrophy type 1A (MDC1A) using the CRISPR activation system in m