Filetype
We study a simple heteropolymer model containing sequence-independent local interactions on both square and triangular lattices. Sticking to a two-letter code, we investigate the model for varying strength κ of the local interactions; κ=0 corresponds to the well-known HP model [K. F. Lau and K. A. Dill, Macromolecules 22, 3986 (1989)]. By exhaustive enumerations for short chains, we obtain all str
The thermodynamic behavior of a three-dimensional off-lattice model for protein folding is probed. The model has only two types of residues, hydrophobia and hydrophilic. In absence of local interactions, native structure formation does not occur for the temperatures considered. By including sequence independent local interactions, which qualitatively reproduce local properties of functional protei
The purpose of this paper is to investigate the possibilities of optimizing the production of paper pulp in a Conical Disc (CD) refiner for different production rates, taking into account the variables that are thought to be the most important for the production. These include three separate dilution waters, conical disc gap and flat gap. Another task is to compare the values of these variables af
Although it is a central question in biology, how cell shape controls intracellular dynamics largely remains an open question. Here, we show that the shape of Arabidopsis pavement cells creates a stress pattern that controls microtubule orientation, which then guides cell wall reinforcement. Live- imaging, combined with modeling of cell mechanics, shows that microtubules align along the maximal te
Popular Abstract in Swedish Kontroll av fororeningar i dagens fusionsmaskiner aer ett inte alltfor stort problem. De kan dock anvandas for diagnostiskt syfte eftersom deras linjeemission avslojar ett flertal intressanta plasmaparametrar. For att kunna maeta egenskaper som jontemperatur, jondensitet och plasmarotation i ett fusionsplasma, aer det av yttersta vikt att den spektroskopiska tolkningen
Popular Abstract in English This thesis considers a model of high energy particle collisions. The model is based on the so called BFKL formalism which is valid only at low x, that is collisions at very high energies, such as at the LHC. The intial state of the incoming particles are simulated by colour dipoles in transverse space evolved through rapidity. With this approach, all fluctuations are dThis thesis considers a model of high energy particle collisions. The model is based on the so called BFKL formalism which is valid only at low x, that is collisions at very high energies, such as at the LHC. The intial state of the incoming particles are simulated by colour dipoles in transverse space evolved through rapidity. With this approach, all fluctuations are dynamically described, allowi
While pattern formation is studied in various areas of biology, little is known about the noise leading to variations between individual realizations of the pattern. One prominent example for de novo pattern formation in plants is the patterning of trichomes on Arabidopsis leaves, which involves genetic regulation and cell-to-cell communication. These processes are potentially variable due to, e.g
We study a small Anderson-impurity cluster using lattice density functional methods, and try todetermine the exact exchange-correlation (XC) potential via reverse engineering. In doing so we nd singlet{triplet degenerate interacting ground states which cannot be v0-represented in an ensemble-DFT sense. Wealso nd that it is possible to represent a triplet ground state as a pure state, but not the s
This thesis is composed of six papers, which all concern different methods and tools used for the analysis of barcodes in nanochannel-based Optical DNA Mapping (ODM). The first four papers consider densely-labeled barcodes while the last two consider sparsely-labeled barcodes.Paper I presents a combinatorial auction algorithm for contig assembly ussing ODM barcodes as scaffolds.Paper II concerns m
A novel approach for structure alignment is presented, where the key ingredients are: (1) An error function formulation of the problem simultaneously in terms of binary (Potts) assignment variables and real-valued atomic coordinates. (2) Minimization of the error function by an iterative method, where in each iteration a mean field method is employed for the assignment variables and exact rotation
Experimental and computational efforts are constantly made to elucidate mechanisms controlling cell fate decisions during development and reprogramming. One powerful computational method is to consider cell commitment and reprogramming as movements in an energy landscape. Here, we develop Computation of Energy Landscapes of Logical Gene Networks (CELLoGeNe), which maps Boolean implementation of ge
Artificial neural networks is one of the most commonly used machine learning algorithms in medical applications. However, they are still not used in practice in the clinics partly due to their lack of explanatory capacity. We compare two case-based explanation methods to two trained physicians on analysis of electrocardiogram (ECG) data from patients with a suspected acute coronary syndrome (ACS).
I det blomstrande forskningsfältet om planeter och exoplaneter, det vill säga planeter utanför vårat eget Solsystem hittar vi konstant nya planeter och system som alla ger oss pusselbitar till att förstå hur planeter formas och utvecklas. Så för att förstå de observationer vi gör och bedöma hur sannolikt det är att det kan finnas liv på en planet, måste vi förstå alla olika typer av system och hurIn the thriving field of exoplanet research new discoveries are made all the time, and while most of the observed systems can be explained with classical planet formation models - some are much harder to explain. When stars form they are often surrounded by the remaining material of the nebulae they formed from. Some of this remaining material forms into a protoplanetary disk around the protostars
B-cell lymphoma (BCL) heterogeneity represents a key issue, often making the classification and clinical management of these patients challenging. In this pilot study, we outlined the first resolved view of BCL disease heterogeneity on the protein level by deciphering disease-associated plasma biomarkers, specific for chronic lymphocytic leukemia, diffuse large B-cell lymphoma, follicular lymphoma
The paper presents an analysis of context within which FAR, the Swedish professional association representing accountants has developed and revised the Code of Ethics from 1923 to 1995. The purpose is to enhance our understanding of the choices made as to what ethical rules were verbalized or codified and the motivations behind the codification. Building on Birkett and Evans’ (2005) model for orga
Alla gillar vi att observera världen runtom oss. Vi observerar hur natthimlens stjärnor rör sig från öst mot väst nattetid och vi ser hur Månen ändrar sin position bland stjärnorna från en natt till en annan.I denna interaktiva visning observerar vi Solens rörelse över himlavalvet. Märkte du var den steg över horisonten i morse? Stiger den alltid över horisonten just där? Var kommer solnedgången aWe are all observers of our Universe. We see the stars moving from East to West at night and we see the Moon move among the stars from day to day.But let us consider the Sun. Did you notice where the Sun rose above the horizon this morning? Does it always rise in the same location? Where will the Sun set tonight? Where would it set if we were in Australia?This is an interactive show where we obser
Katedralen var en av de mest centrala institutionerna i det medeltida samhället. Kring stiftets biskop samlades den kyrkliga makten och dåtidens elit, dygnet runt firades gudstjänster och här utbildades stiftets präster. En viktig roll för livet i och kring katedralen hade domkapitlet eller katedralkapitlet, dvs det organiserade prästerskap som betjänade domkyrkan och bistod biskopen.I mitt avhandThe cathedral was one of the most important institutions in medieval Europe. The local as well as ecclesiastical elite gathered around it and its bishop; the liturgy was celebrated day and night, year after year; the cathedral served as educational institution of the clergy. The cathedral chapter, i.e. the organized clergy that served at the cathedral, played a decisive part in all this.The overar
Carmen valde att läsa masterprogrammet i biokemi vid Lunds universitet för dess flexibilitet och praktiska inriktning. Programmets kursutbud, många laborativa moment och en stöttande lärandemiljö har förberett henne väl för en fortsatt karriär inom akademin och forskningen.Carmen chose the Master’s programme in Biochemistry at Lund University for its flexibility and strong practical focus. The programme’s range of courses, lab-based training and supportive environment have prepared her well for a continued career in academia and research.
Genom äktenskapsförord har makar möjlighet att reglera sina egendomsförhållanden vid en eventuell skilsmässa. Om en make anser att ett eller flera villkor i äktenskapsförordet är oskäliga kan denne åberopa jämkning enligt bestämmelsen i 12 kap. 3 § Äktenskapsbalken (SFS 1987:230) (ÄktB). I förarbetena till lagen, prop.1986/87:1, uttalade departementschefen att bestämmelsen ska tillämpas restriktivThrough prenuptial agreements, spouses have the opportunity to regulate their economic conditions in case of a divorce. If one spouse finds one or more conditions in the agreement to be unreasonable, they can appeal for adjustment of this through the regulation in 12 ch. 3 § ÄktB (the Swedish martial law). In the legislative history of the law, prop.1986/87:1, the minister expressed that the admin
