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Minimum carbon uptake controls the interannual variability of ecosystem productivity in tropical evergreen forests

Tropical evergreen forests contribute an important part to the interannual variability (IAV) of the global terrestrial gross primary productivity (GPP). Due to its year-round growing-season, high minimum carbon uptake (GPPmin) and dry season greening-up, the key processes driving the GPP variability across seasonal to interannual scale are still in debate. Here, we analyzed the time-series of FLUX

Floral evidence for high summer temperatures in southern Scandinavia during 15–11 cal ka BP

The global climate transition from the Lateglacial to the Early Holocene is dominated by a rapid warming trend driven by an increase in orbital summer insolation over high northern latitudes and related feedbacks. The warming trend was interrupted by several abrupt shifts between colder (stadial) and warmer (interstadial) climate states following instabilities of the Atlantic Meridional Overturnin

Drought legacy affects microbial community trait distributions related to moisture along a savanna‐grassland precipitation gradient

Ecosystem models commonly use stable‐state assumptions to predict responses of soil microbial functions to environmental change. However, past climatic conditions can shape microbial functional responses resulting in a ‘legacy effect’. For instance, exposure to drier conditions in the field may shape how soil microbial communities respond to subsequent drought and drying and rewetting (DRW) event

Actual European forest management by region, tree species and owner based on 714,000 re-measured trees in national forest inventories

Background European forests have a long record of management. However, the diversity of the current forest management across nations, tree species and owners, is hardly understood. Often when trying to simulate future forest resources under alternative futures, simply the yield table style of harvesting is applied. It is now crucially important to come to grips with actual forest management, now t

Soil carbon insures arable crop production against increasing adverse weather due to climate change

Intensification of arable crop production degrades soil health and production potential through loss of soil organic carbon. This, potentially, reduces agriculture's resilience to climate change and thus food security. Furthermore, the expected increase in frequency of adverse and extreme weather events due to climate change are likely to affect crop yields differently, depending on when in the gr

Class Id ribonucleotide reductase utilizes a Mn2(IV,III) cofactor and undergoes large conformational changes on metal loading

Outside of the photosynthetic machinery, high-valent manganese cofactors are rare in biology. It was proposed that a recently discovered subclass of ribonucleotide reductase (RNR), class Id, is dependent on a Mn2(IV,III) cofactor for catalysis. Class I RNRs consist of a substrate-binding component (NrdA) and a metal-containing radical-generating component (NrdB). Herein we utilize a combination of

Molecular biology of IDDM

The clinical onset of insulin-dependent diabetes is associated with several autoimmune phenomena including islet cell antibodies, glutamic acid decarboxylase (the GAD65 isoform) autoantibodies (GAD65Ab) as well as insulin autoantibodies. The molecular cloning of these autoantigens has permitted the development of precise and reproducible antibody immunoassays to identify marker-positive patients a

Prevalence of sexually transmitted infections (HIV, hepatitis B virus, herpes simplex virus type 2, and syphilis) in pregnant women in Ethiopia : Trends over 10 years (2005-2014)

OBJECTIVES: This study was performed to determine the trends in seroprevalence of four major sexually transmitted infections (STIs) (HIV, hepatitis B virus (HBV), herpes simplex virus type 2 (HSV-2), and syphilis) over a 10-year period (2005-2014) in pregnant women in Ethiopia.METHODS: Pregnant women (15-49 years old) who were enrolled in the antenatal care-based national HIV surveillance were inc

Activating phosphorylation of the Kin28p subunit of yeast TFIIH by Cak1p

Cyclin-dependent kinase (CDK)-activating kinases (CAKs) carry out essential activating phosphorylations of CDKs such as Cdc2 and Cdk2. The catalytic subunit of mammalian CAK, MO15/Cdk7, also functions as a subunit of the general transcription factor TFIIH. However, these functions are split in budding yeast, where Kin28p functions as the kinase subunit of TFIIH and Cak1p functions as a CAK. We sho

Contributions of the troposphere and stratosphere to CH4 model biases

Inverse modelling is a useful tool for retrieving CH4 fluxes; however, evaluation of the applied chemical transport model is an important step before using the inverted emissions. For inversions using column data one concern is how well the model represents stratospheric and tropospheric CH4 when assimilating total column measurements. In this study atmospheric CH4 from three inverse models is com

Allele-selective RUNX1 binding regulates P1 blood group status by transcriptional control of A4GALT

P1 and Pk are glycosphingolipid antigens synthesized by the A4GALT-encoded α1,4-galactosyltransferase, using paragloboside and lactosylceramide as acceptor substrates, respectively. In addition to the compatibility aspects of these histo-blood group molecules, both constitute receptors for multiple microbes and toxins. Presence or absence of P1 antigen on erythrocytes determines the common P1 (P1+

Management and outcomes following emergency surgery for traumatic brain injury – A multi-centre, international, prospective cohort study (the Global Neurotrauma Outcomes Study)

Introduction: Traumatic brain injury (TBI) accounts for a significant amount of death and disability worldwide and the majority of this burden affects individuals in low-and-middle income countries. Despite this, considerable geographical differences have been reported in the care of TBI patients. On this background, we aim to provide a comprehensive international picture of the epidemiological ch

Artificial light at night, in interaction with spring temperature, modulates timing of reproduction in a passerine bird

The ecological impact of artificial light at night (ALAN) on phenological events such as reproductive timing is increasingly recognized. In birds, previous experiments under controlled conditions showed that ALAN strongly advances gonadal growth, but effects on egg-laying date are less clear. In particular, effects of ALAN on timing of egg laying are found to be year-dependent, suggesting an inter

Weak population structure in the North American house wren Troglodytes aedon

Cryptic genetic differentiation is being increasingly documented in birds and other organisms using genome-wide variation. A recent example of cryptic genetic differentiation in a widespread species with conserved morphology is the northern house wren Troglodytes aedon. We found that, despite extremely similar morphology and no documented vocal differences, the two subspecies of the northern house

Sex pheromone biosynthesis in the Oriental fruit moth Grapholita molesta involves Δ8 desaturation

The Oriental fruit moth Grapholita molesta is distributed throughout temperate regions and considered to be a pest in peach production and other high-value fruit crops in the rose family. Insecticide treatment has led to resistance development, but the use of sex pheromones in pest management has shown great promise. We investigated the pheromone biosynthesis pathway in G. molesta with the aim of

Embedded disposability : A cultural political economy of plastics

Plast präglar i stort sett allting i det moderna livet och bidrar till miljöförstöring och avfallsgenerering på global nivå. Denna avhandling undersöker hur plastavfall blev djupt inbäddat i Sveriges kulturella, politiska och ekonomiska strukturer. Med hjälp av ett ramverk baserat på kulturell politisk ekonomi (CPE) används tre perspektiv - hegemoni, inlåsningseffekter och praktiker - för att analPlastic disposability is a pervasive feature of modern life, contributing to environmental degradation and waste generation on a global scale. This dissertation investigates how plastic disposability became deeply embedded within Sweden's cultural, political, and economic structures. Using a Cultural Political Economy (CPE) framework, it applies three lenses – hegemony, lock-in, and practice – to

Cleavage of Cartilage Oligomeric Matrix Protein (COMP) by ADAMTS4 generates a neoepitope associated with osteoarthritis and other forms of degenerative joint disease

Osteoarthritis (OA) is a highly prevalent joint disease, affecting millions of people worldwide and characterized by degradation of articular cartilage, subchondral bone remodeling and low-grade inflammation, leading to pain, stiffness and disability. Cartilage Oligomeric Matrix Protein (COMP) is a major structural component of cartilage and its degradation has been proposed as a marker of OA seve

Transition metal transporting P-type ATPases : terminal metal-binding domains serve as sensors for autoinhibitory tails

Copper is an essential micronutrient and yet is highly toxic to cells at elevated concentrations. P1B-ATPase proteins are critical for this regulation, providing active extrusion across cellular membranes. One unique molecular adaptation of P1B-ATPases compared to other P-type ATPases is the presence of metal-binding domains (MBDs) at the cytosolic termini, which however are poorly characterized w