Filetype
Immunotherapy is revolutionizing cancer treatment, but success is limited to a fraction of patients. Tumor immunosurveillance and immunotherapy relies on presentation of tumor-associated antigens by conventional dendritic cells type 1 (cDC1). However, tumors develop mechanisms to avoid immune recognition such as downregulation of antigen presentation and exclusion of cDC1. We have previously demon
Aims: Transforming growth factor-beta (TGF-β) exists in three isoforms TGF-β1, -β2, and -β3. TGF-β1 has been suggested to be important for maintaining plaque stability, yet the role of TGF-β2 and -β3 in atherosclerosis remains to be investigated. This study explores the association of the three isoforms of TGF-β with plaque stability in the human atherosclerotic disease. Methods and results: TGF-β
Tomographic X-ray imaging techniques offer novel opportunities for studying membranes and membrane processes in 3D on a spatial resolution not seen before. Traditional 2D imaging techniques used to characterise membranes have limitations that can be overcome by tomographic X-ray imaging. Tomographic X-ray imaging can provide information in 2D/3D or 4D (3D plus time) on membranes, membrane modules,
BackgroundRight ventricular (RV) function is a major determinant of outcome in patients with pulmonary hypertension. Cardiac magnetic resonance (CMR) is gold standard to assess RV ejection fraction (RVEFCMR), however this is a crude measure. New CMR measures of RV function beyond RVEFCMR have emerged, such as RV lateral atrio-ventricular plane displacement (AVPDlat), maximum emptying velocity (S’C
Stem cell transplantation is a cornerstone in the treatment of blood malignancies. The most common method to harvest stem cells for transplantation is by leukapheresis, requiring mobilization of CD34+ hematopoietic stem and progenitor cells (HSPCs) from the bone marrow into the blood. Identifying the genetic factors that control blood CD34+ cell levels could reveal new drug targets for HSPC mobili
Vid marktekniska undersökningar i finkorniga jordar är det av stor vikt att korrekt kunna bestämma den odränerade skjuvhållfastheten. Detta görs idag vanligtvis ute i fält med en uppsjö av sonderingsmetoder som ger olika mått på hur fast jorden är. För homogena leror och sand finns det en stadig empirisk grund för hur dessa sonderingsparametrar räknas om till odränerad skjuvhållfasthet, men hur seThe undrained shear strength is a key parameter in the design process of geotechnical structures. One of the most frequently used methods to investigate this parameter is the cone penetration test (CPT). The CPT does not measure the undrained shear strength directly, but instead the resistance that a conic probe encounters as it is pushed into the ground. A calibration factor, the cone factor (Nkt
The purpose of the work was to investigate methods to achieve satisfaction with one’s own performance during and after a concert, using my own practice as point of departure. This has been investigated through interviews with musicians, continuous keeping of a logbook and literature studies. The goal was to be able to use the collected information to feel satisfied with my playing during my gradua
DevOps has significantly improved the software development life-cycle by enabling fast, automated, and continuous integration and deployment (CI/CD). However, its application to Cyber-Physical Systems (CPS) presents unique challenges that require rethinking of traditional practices. DevOps in CPS becomes even more challenging when we consider sustainability, which is becoming increasingly importan
Recessive diseases arise when both copies of a gene are impacted by a damaging genetic variant. When a patient carries two potentially causal variants in a gene, accurate diagnosis requires determining that these variants occur on different copies of the chromosome (that is, are in trans) rather than on the same copy (that is, in cis). However, current approaches for determining phase, beyond pare
Den europeiska unionen tampas med låg folklig legitimitet, och hävdar många politiska bedömare, ett demokratiskt underskott. I det förhandenvarande arbetet, som är av normativ karaktär, tar sig författaren an detta ämne utifrån ett deltagardemokratiskt perspektiv, vilket han polemiserar mot ett elitdemokratiskt. Dessa demokratimodellers relationer till republikanismen och liberalismen redogörs där
Det hållbara arbete som idag utförs på olika enheter i staden ser ut att vara beroende av individers engagemang, snarare än deras kunskap kring vilka miljömål som ska uppnås av förvaltningen och vidare den specifika enheten. Osäkerheter bland medarbetarna kring; att de ska arbeta hållbart, vem som ansvarar för det hållbara arbetet, hur de ska arbeta hållbart samt vilka konsekvenser det får att arb
BackgroundLongitudinal data on weight change, its timing, and the age of obesity onset in relation to cause-specific mortality are limited.MethodsFrom ODDS, a nationwide pooled cohort study in Sweden, we included 258,269 men and 361,784 women with at least three weight assessments between ages 17 and 60, collected in 1963–2015. We applied linear mixed-effects models to estimate weight trajectories
With this audio paper, our aim is to explore the connection between sound and democracy. Recognizing the multifaceted nature of this field, we approach it through the notion of care and an empirical analysis of the democratic implications of trying to regulate sound in public spaces. We examine ISO standards as one example of the many attempts to control sound in both public and private spaces. St
The events are described in the languages used at each event. Rättsfallsseminarium om Foxhouse-domen i Högsta domstolenOnsdagen 5 december kl. 11.00-12.15Advokatfirman Vinge, MalmöHögsta domstolen meddelade den 2 november 2023 dom i mål T 8042-21 (Foxhouse). I avgörandet behandlar Högsta domstolen förutsättningarna för vinstutdelning, återbäringsskyldighet och bristtäckningsansvar enligt aktiebola
https://www.aclu.lu.se/en/events/past-events/2023 - 2026-05-19
Totalbudget för Lunds universitet 2022 Postadress Box 117, 221 00 Lund Telefon, 046-222 8620 E-post filip.bengtsson@eken.lu.se Webbadress www.lu.se Universitetsstyrelsen Totalbudget för Lunds universitet 2022 • Budgeterat resultat för 2022 visar på ett överskott på 29 mnkr fördelat på ett överskott på 1,7 mnkr inom utbildning och ett överskott på 27,7 mnkr inom forskning. • Intäkterna förväntas ök
https://www.ekonomiwebben.lu.se/sites/ekonomiwebben.lu.se/files/2023-10/fullstandigt_beslut_totalbudget_2022.pdf - 2026-05-20
Professor Contact details Email: maria [dot] messing [at] fysik [dot] lu [dot] se Phone: +46 46 222 36 91 Mobile: +46 70 640 61 94Organisation Solid State Physics Visiting address: Professorsgatan 1, Lund Room number: B102 Service point: 14 WebpageMaria Messings profile in Lund University research portalOther affiliations Coordinator LTH Profile Area: Nanoscience and Semiconductor Technology Membe
https://www.sljus.lu.se/maria-messing - 2026-05-20
