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Combined genome and transcriptome sequencing to investigate the plant cell wall degrading enzyme system in the thermophilic fungus Malbranchea cinnamomea

Background: Genome and transcriptome sequencing has greatly facilitated the understanding of biomass-degrading mechanisms in a number of fungal species. The information obtained enables the investigation and discovery of genes encoding proteins involved in plant cell wall degradation, which are crucial for saccharification of lignocellulosic biomass in second-generation biorefinery applications. T

Constructive friction? Exploring patterns between Educational Research and The Scholarship of Teaching and Learning

While educational research (EdR) and the Scholarship of Teaching and Learning (SoTL) are overlapping fields there remains considerable friction between the two. Shulman, (2011, p. 5), recounts a situation when an EdR colleague accused him “of contributing to the bastardization of the field by encouraging faculty members who were never trained to conduct educational or social science research to en

Children with Plasmodium vivax infection previously observed in Namibia, were Duffy negative and carried a c.136G > A mutation

Background: In a previous study, using a molecular approach, we reported the presence of P. vivax in Namibia. Here, we have extended our investigation to the Duffy antigen genetic profile of individuals of the same cohort with and without Plasmodium infections. Methods: Participants with P. vivax (n = 3), P. falciparum (n = 23) mono-infections and co-infections of P. vivax/P. falciparum (n = 4), a

A python framework for solving advection-diffusion problems

This paper discusses a Python interface for the recently published Dune-Fem-DG module which provides highly efficient implementations of the Discontinuous Galerkin (DG) method for solving a wide range of non linear partial differential equations (PDE). Although the C++ interfaces of Dune-Fem-DG are highly flexible and customizable, a solid knowledge of C++ is necessary to make use of this powerful

On compositions of special cases of Lipschitz continuous operators

Many iterative optimization algorithms involve compositions of special cases of Lipschitz continuous operators, namely firmly nonexpansive, averaged, and nonexpansive operators. The structure and properties of the compositions are of particular importance in the proofs of convergence of such algorithms. In this paper, we systematically study the compositions of further special cases of Lipschitz c

Alpha-ketoglutarate decreases serum levels of C-terminal cross-linking telopeptide of type I collagen (CTX) in postmenopausal women with osteopenia: Six-month study

Several studies have shown that alpha-ketoglutaric acid (AKG) increases serum levels of proline and has beneficial effects on skeletal development. We studied the effect of alpha-ketoglutaric (AKG) acid calcium salt (6 g AKG and 1,68 Ca/day) or calcium alone (1.68 Ca/day) on serum C-terminal cross-linked telopeptide of type I collagen (CTX) and osteocalcin (OC), as well as lumbar spine bone minera

Expanding Bioenergy in Europe

Despite apparently favourable conditions for investment in the bioenergy sector provided by sustained high oil prices and a multitude of policy support measures throughout the EU that are ostensibly intended to create improved economic conditions, many industrialists and investors are still apparently wary of engagement. National policy interventions intended to support and to expand the bioenergy

Leadership in specialist palliative home care teams : A qualitative study

Aim: The aim of this study was to describe team leaders' experiences of facilitators and barriers of leadership in specialist palliative home care teams. Background: For effective teamwork in specialist palliative care, leadership is crucial; however, defining and agreeing on what leadership comprises may be challenging. In palliative care, teamwork is recognized as imperative for multiprofessiona

Computational health engineering applied to model infectious diseases and antimicrobial resistance spread

Infectious diseases are the primary cause of mortality worldwide. The dangers of infectious disease are compounded with antimicrobial resistance, which remains the greatest concern for human health. Although novel approaches are under investigation, the World Health Organization predicts that by 2050, septicaemia caused by antimicrobial resistant bacteria could result in 10 million deaths per year

Differential Tuning to Visual Motion Allows Robust Encoding of Optic Flow in the Dragonfly

Visual cues provide an important means for aerial creatures to ascertain their self-motion through the environment. In many insects, including flies, moths, and bees, wide-field motion-sensitive neurons in the third optic ganglion are thought to underlie such motion encoding; however, these neurons can only respond robustly over limited speed ranges. The task is more complicated for some species o

Event-related potentials to visual processing of incongruities in negated and affirmative sentences

In spite of the fact that negation has been the focus of many studies, the way it is processed in human communication still eludes us. Previous studies of negation using event-related potentials (ERPs) have reported inconclusive results as to whether or not negation poses difficulties for processing. While some have found that negation is initially ignored and incongruities in negated sentences do

Neurofilament light chain on intensive care admission is an independent predictor of mortality in COVID-19 : a prospective multicenter study

BACKGROUND: Neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and total-tau protein (tau) are novel blood biomarkers of neurological injury, and may be used to predict outcomes in critical COVID-19.METHODS: A prospective multicentre cohort study of 117 consecutive and critically ill COVID-19 patients in six intensive care units (ICUs) in southern Sweden between May and Novem

Safeguarding Food Industry : Understanding Cyberthreats and Ensuring Cybersecurity

The food industry stands as one of the most vital manufacturing sectors globally, with an ever-increasing reliance on digitalization and technology-driven processes. However, this advancement comes with an inherent risk of cyberattacks, encompassing data breaches and system disruptions, which can severely impact production and disrupt the entire food supply chain. Consequently, such cyberthreats c