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ORIGINAL ARTICLE Efficient transduction of neurons using Ross River glycoprotein-pseudotyped lentiviral vectors J Jakobsson, T Tolstrup Nielsen, K Staflin, B Georgievska and C Lundberg Department of Experimental Medical Research, Section for Neuroscience, Wallenberg Neuroscience Center, Lund University, Lund, Sweden Lentiviral vectors are promising tools for CNS gene transfer since they efficientl

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/3302701.pdf - 2026-05-18

PROGRAM VT 2022 ODEUM LUNDS UNIVERSITETS MUSIKCENTRUM TEMA: NATURSKILDRINGAR Välkomna till vårens evenemangsserie vid Odeum, fylld av konserter, gästspel och samtal om musik! Temat för våren är Naturskildringar. Ett brett tema där vi inte minst vill lyfta fram de pågående klimatförändringarna och vad dessa för med sig för skapande musiker och tonsättare. Några av de svenska tonsättare som skrivit

https://www.odeum.lu.se/sites/odeum.lu.se/files/2022-01/Odeum_program_VT_2022_0.pdf - 2026-05-18

CFE wp- Nr 20 1EU Treaty Reform in Theoretical Perspective EU Treaty Reform in Theoretical Perspective An Empirical Exploration of Liberal Intergovern- mentalism and Historical Institutionalism Björn Arvidsson bjorn.arvidsson.763@student.lu.se 2 CFE Working paper series no. 20 CENTRE FOR EUROPEAN STUDIES AT LUND UNIVERSITY: Box 52 Phone: +46 (0)46-222 88 99 SE-221 00 LUND Fax: +46 (0)46-222 40 06

https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2020-12/cfewp20.pdf - 2026-05-18

PROGRAM VT 2022 ODEUM LUNDS UNIVERSITETS MUSIKCENTRUM TEMA: NATURSKILDRINGAR Välkomna till vårens evenemangsserie vid Odeum, fylld av konserter, gästspel och samtal om musik! Temat för våren är Naturskildringar. Ett brett tema där vi inte minst vill lyfta fram de pågående klimatförändringarna och vad dessa för med sig för skapande musiker och tonsättare. Några av de svenska tonsättare som skrivit

https://www.odeum.lu.se/en/sites/odeum.lu.se.en/files/2022-03/ODEUM_programbok_VT_2022.pdf - 2026-05-18

Osteoarthritis (OA) remains the most challenging arthritic disorder, with a high burden of disease and no available disease-modifying treatments. Symptomatic early-stage OA of the knee (the focus of this Review) urgently needs to be identified and defined, as efficient early-stage case finding and diagnosis in primary care would enable health-care providers to proactively and substantially reduce

The mobile research lab is an emerging research methodology increasingly applied in urban studies to investigate phenomena like places, infrastructures, nature and inhabitants of cities. This essay critically explores this relatively new methodology, also known as ‘mobile labs’, as part of in-situ research for a two-year research project supported by the International Fellowship Program of the Jap

Bayesian decision analysis is a useful method for risk management decisions, but is limited in its ability to consider severe uncertainty in knowledge, and value ambiguity in management objectives. We study the use of robust Bayesian decision analysis to handle problems where one or both of these issues arise. The robust Bayesian approach models severe uncertainty through bounds on probability dis

Light microscopy has been a favorite tool of biological studies for almost a century, recently producing detailed images with exquisite molecular specificity achieving spatial resolution at nanoscale. However, light microscopy is insufficient to provide chemical information as a standalone technique. An increasing amount of evidence demonstrates that optical photothermal infrared microspectroscopy

The MEDIM study reports that Immigrants from the Middle East to Sweden – independently of other diabetes related risk factors – have a twice as high type 2 diabetes risk as compared to non-immigrated Swedes. Diabetes onset occurs 6 years earlier in this group and is partly explained by family history and/or obesity. But the MEDIM study has identified that Middle Eastern background per se is an ind

Astrocytes are one of the major cell types in the central nervous system and are indispensable for brain development and function. The human brain and human astrocytes have unique structures and functions that are not present in other animal species. Studies of fundamental astrocyte biology in humans and their role in neurological disease have been hindered by shortage of native human astrocytes f

Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest malignancies and potentially curable only with radical surgical resection at early stages. The tumor microenvironment has been shown to be central to the development and progression of PDAC.A better understanding of how early human PDAC metabolically communicates with its environment and differs from healthy pancreas could help improve

Background: The risk of adults with a congenital heart defect (ACHD) developing heart failure, stroke, arrhythmias, and the need for valve replacement is increased compared to healthy peers. Evidence for the use of novel oral anticoagulants (NOAC) in this patient group is still lacking and vitamin K antagonists (VKA) are the primary choice for patients with a mechanical valve. The present aim was

Budding off from the broader developmental biology and stem cell research fields, cellular reprogramming is now established as a prominent discipline in its own right. Direct cell reprogramming is defined as the cell fate conversion of a somatic cell toward another identity without a pluripotent intermediate state. In addition to the opportunity for mechanistic dissection of lineage commitment in

Human pluripotent stem cells (hPSCs) are intrinsically able to self-organize into cerebral organoids that mimic features of developing human brain tissue. These three-dimensional structures provide a unique opportunity to generate cytoarchitecture and cell-cell interactions reminiscent of human brain complexity in a dish. However, current in vitro brain organoid methodologies often result in intra

Single-cell phenotyping based on biophysical properties is a promising tool to distinguish cell types and their response to a given condition, and charting such properties also enables optimization of cell separations. Isoacoustic focusing, where cells migrate to their points of zero acoustic contrast in an acoustic impedance gradient, added the effective acoustic impedance of cells to the directo

Background: The residual cardiovascular risk in subjects receiving guideline-recommended therapy is related to persistent vascular inflammation and IL-6 represents a target for its treatment. IL-6 binds to receptors on leukocytes and hepatocytes and/or by forming complexes with soluble IL-6 receptors (sIL-6R) binding to gp130 which is present on all cells. Here we aimed to estimate the association