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BACKGROUND: Patients with diabetes have increased rates of major adverse cardiac events (MACEs). We hypothesized that this is explained by diabetes-associated differences in coronary plaque morphology and lipid content. METHODS: In PROSPECT II (Providing Regional Observations to Study Predictors of Events in the Coronary Tree), 898 patients with acute myocardial infarction with or without ST-segme

Multiple sclerosis leads to diffuse damage of the central nervous system, affecting also the normal-appearing white matter. Demyelination and axonal degeneration reduce regional fractional anisotropy in normal-appearing white matter, which can be routinely mapped with diffusion tensor imaging. However, the standard fractional anisotropy metric is also sensitive to physiological variations in orien

Background: Neuropsychiatric symptoms (NPS) are common in individuals with Alzheimer’s disease (AD) dementia, but substantial heterogeneity exists in the manifestation of NPS. Sex differences may explain this clinical variability. We aimed to investigate the sex differences in the prevalence and severity of NPS in AD dementia. Methods: Literature searches were conducted in Embase, MEDLINE/PubMed,

IMPORTANCE Moderate-grade adolescent idiopathic scoliosis (AIS) may be treated with full-time bracing. For patients who reject full-time bracing, the effects of alternative, conservative interventions are unknown. OBJECTIVE To determine whether self-mediated physical activity combined with either nighttime bracing (NB) or scoliosis-specific exercise (SSE) is superior to a control of physical activ

Background: Previous studies demonstrated increases in diagnostic confidence and change in patient management after amyloid-PET. However, studies investigating longitudinal outcomes over an extended period of time are limited. Therefore, we aimed to investigate clinical outcomes up to 9 years after amyloid-PET to support the clinical validity of the imaging technique. Methods: We analyzed longitud

Background: In sub-Saharan Africa, truckers and female sex workers (FSWs) have high HIV risk and face challenges accessing HIV testing. Adding HIV self-testing (HIVST) to standard of care (SOC) programs increases testing rates. However, the underlying mechanisms are not fully understood. HIVST may decrease barriers (inconvenient clinic hours, confidentiality concerns) and thus we would expect a gr

Background and objective: Patients diagnosed with grade group (GG) 1 prostate cancer (PCa) following treatment for benign disease (“incidental” PCa) are typically managed with active surveillance (AS). It is not known how their outcomes compare with those observed in patients diagnosed with GG1 on biopsy. We aimed at determining whether long-term oncologic outcomes of AS for patients with GG1 PCa

Just nu finns det en möjlighet för politikerna att lägga om stadsplaneringen så att det blir möjligt att nå FN:s hållbarhetsmål. Det skriver åtta forskare som arbetar med miljö- och hälsofrågor.

Background: Bococizumab is a humanized monoclonal antibody that inhibits proprotein convertase subtilisin-kexin type 9 (PCSK9) and reduces levels of low-density lipoprotein (LDL) cholesterol. We sought to evaluate the efficacy of bococizumab in patients at high cardiovascular risk. Methods: In two parallel, multinational trials with different entry criteria for LDL cholesterol levels, we randomly

Background Postural orthostatic tachycardia syndrome (POTS) is a variant of cardiovascular autonomic disorder occurring predominantly in young women. POTS is characterized by an excessive heart rate increase when assuming upright posture accompanied by symptoms of orthostatic intolerance. The pathophysiology of POTS has not been fully established and is believed to be multifactorial. Purpose We a

Urgent structural change is required in higher education to allow collaboration both within and acrossuniversities so that achieving a rapid sustainability transition can become the overarching and mainpurpose of education, research and work in society. A review of the literature reveals that fragmentation,caused by traditional hierarchical faculty and disciplinary organisation, is a major obstacl

Grandparents’ involvement in their adult children’s families has increased in recent decades, especially in relation to care arrangements around grandchildren. This ‘new army of proxy parents’ calls for the need to critically analyse grandparental care. Drawing on a study on intergenerational care in Sweden, involving grandparents, adult children and grandchildren (63 interviewees including 28 gra

Background: Cardiovascular Magnetic Resonance (CMR) enables non-invasive quantification of cardiac output (CO) and thereby cardiac index (CI, CO indexed to body surface area). The aim of this study was to establish if CI decreases with age and compare the values to CI for athletes and for patients with congestive heart failure (CHF). Methods: CI was measured in 144 healthy volunteers (39 +/- 16 ye

The source contributions to carbonaceous PM2.5 aerosol were investigated at a European background site at the edge of the Po Valley, in Northern Italy, during the period January-December 2007. Carbonaceous aerosol was described as the sum of 8 source components: primary (1) and secondary (2) biomass burning organic carbon, biomass burning elemental carbon (3), primary (4) and secondary (5) fossil

Background: Several attempts to increase the locoregional control in locally advanced lung cancer including concurrent chemotherapy, accelerated fractionation and dose escalation have been made during the last years. As the EGFR directed antibody cetuximab has shown activity concurrent with radiotherapy in squamous cell carcinoma of the head and neck, as well as in stage IV NSCLC combined with che

Årsrapport 2004 för Enheten för medicinens historia, Medicinska Fakulteten, Lunds universitet 1 Årsrapport 2012 för Enheten för medicinens historia, Medicinska Fakulteten, Lunds universitet Enheten för medicinens historia har under året 2012 fortsatt sin verksamhet som en fristående enhet inom Institutionen för kliniska vetenskaper (IKVL) i Lund (prefekt Bo Baldetorp, sektion 5 med chef Vineta Fel

https://www.medicinhistoria.lu.se/sites/medicinhistoria.lu.se/files/arsrapport_mh_final_2012.pdf - 2026-07-15

Hjärnkoll förändrar attityder Uppföljning och effektutvärdering av Hjärnkoll Datum 2012-06-01 Diarienummer 2012/0002 Handisam, Myndigheten för handikappolitisk samordning, 2012 Titel: Hjärnkoll förändrar attityder Handisam Serie A 2012:4 (diarienummer 2012/0002) Utredare: Rickard Bracken Rapporten finns att ladda ner från Handisams webbplats www.handisam.se. Alternativa format kan beställas från H

https://www.cepi.lu.se/sites/cepi.lu.se/files/hjarnkoll_forandrar_attityder.pdf - 2026-07-15

Rapport vecka 38 (publicerad 2020-09-23) COVID Symptom Study Innehåll Bakgrund 2 Metod 2 Etiskt godkännande 5 Aktuell status 5 10 postnummerområden med högst andel studiedeltagare med symtom överensstämmande med covid-19 den 21 september . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 10 postnummerområden med lägst andel studiedeltagare med symtom överensstämmande med

https://www.covid19app.lu.se/sites/covid19app.lu.se/files/rapport_vecka38_coss.pdf - 2026-07-15