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IgG glycan hydrolysis by EndoS diminishes the pro-inflammatory properties of immune complexes from patients with SLE - a possible new treatment?

OBJECTIVE.: Systemic lupus erythematosus (SLE) is an autoimmune disease with chronic or episodic inflammation in several organ systems, related to the presence of circulating and tissue-deposited immune complexes (ICs) which stimulate leukocytes through FcγRs with subsequent inflammation. Treatment with EndoS, an IgG glycan hydrolyzing bacterial enzyme from Streptococcus pyogenes, has shown benefi

Den pedagogiska praktikens janusansikte: om det kommunikativa handlandets didaktiska villkor och konsekvenser

Popular Abstract in Swedish Villkoren för utbildning och undervisning förändras i väsentliga avseenden i takt med samhällets tilltagande komplexitet. Det är många gånger svårt för både lärare och elever att veta hur man på bästa sätt ska orientera sitt pedagogiska handlande. Med utgångspunkt från tre pedagogiska kontexter - grundskolan, de särskilda ungdomshemmen och grundskollärarutbildningen - pPedagogical practice is, in several important considerations, contradictory in character. In this dissertation attenention is drawn towards the field of tension that prevails between pedagogical action, which can be descibed in terms of strategic processes and communicative pedagogical action. While the former places the preconditions for effective knowledge development of the individual at the ce

Deliberate self-harm behavior among young violent offenders

Deliberate self-harm behavior (DSH) can have profound effects on a person’s quality of life, and challenges the health care system. Even though DSH has been associated with aggressive interpersonal behaviors, the knowledge on DSH in persons exhibiting such behaviors is scarce. This study aims to (1) specify the prevalence and character of DSH, (2) identify clinical, neurocognitive, psychosocial, a

Rural Gentrification in Desakota : Farmland Politics, Alternative Food Networks, and the Emergence of New Farmers in Taiwan

Efter en landreform, som genomfördes i slutet av 40- och i början av 50-talet, blev de flesta taiwanesiska bönderna hemmansägare och odlade marken på små lantegendomar. Denna efterkrigsreform banade väg för en ekonomisk utveckling som väsentligt påverkade och förändrade bondesamhället. När det taiwanesiska jordbruket visade tecken på stagnation på 1970-talet, förändrades böndernas syn på markinnehAfter post-war land reform that took place between 1949 and 1953, most Taiwanese farmers became owner-cultivators working on small landholdings. Post-war land reform paved the foundation for economic development and industrialization, processes that squeezed the agricultural sector and created changes in farming villages. When Taiwanese agriculture showed signs of stagnation in the 1970s, farmers’

Hållbart arbetsliv för äldre medarbetare i Helsingborgs stad

Hållbart arbetsliv för alla åldrar i Helsingborgs stadI Sverige har det av samhällsekonomiska orsaker föreslagits att ålderspensionen ska senareläggas, eftersom pensionssystemet är uppbyggt så att vi ska arbeta två tredjedelar av våra liv. En av de största utmaningarna för den svenska arbetsmarknaden är att göra arbetslivet hållbart så att fler klarar av att arbeta till en högre ålder. För att fle

Financial assessment of reusing materials in buildings : Comparing financial potential of wood, concrete, and glass reuse

Buildings are responsible for a third of global greenhouse gas emissions, with much of their life cycle impacts resulting from embodied impacts of building materials. One solution to reduce embodied emissions is to use of secondary materials such as by-products and waste materials for producing building materials (in this study referred to as reuse solutions). While this is reported to have positi

Power system damping in Iceland based on phasor measurements

Phasor measurement signals are used as only input to a wide-area power system stabilizer to increase interarea mode damping of the Icelandic system. Modal analysis and time simulations of a detailed model show that frequency difference as PSS input gives a damping improvement that is robust to drastic changes in system topology. Field data from phasor measurement units indicate high signal quality

Defending the Sex/Gender Binary : The Role of Gender Identification and Need for Closure

In the Western world, gender/sex is traditionally viewed as binary, with people falling into one of two categories: male or female. This view of gender/sex has started to change, triggering some resistance. This research investigates psychological mechanisms underlying that resistance. Study 1 (N = 489, UK) explored the role of individual gender identification in defense of, and attempts to reinfo