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Introduction Breathlessness is debilitating and increases in prevalence with age, with people progressively reducing their everyday activities to ‘self-manage’ it. This study aimed to evaluate the impact of breathlessness on function in terms of activities that have been reduced or ceased (‘compromised’) in older men.Methods A cross-sectional postal survey of Swedish 73-year-old man in the VAScula

• Semiarid regions control a large fraction of the interannual variability in the global terrestrial CO2 sink and of atmospheric CO2 growth rate. • Semiarid ecosystems are characterized by recurring disturbances that alter the regional C budgets. As disturbances are expected to become more frequent or intense in the future, quantifying their contribution to semiarid C balance is crucial. • We revi

Background and purpose: Stereotactic body radiotherapy (SBRT) has emerged as a promising treatment for patients with ventricular tachycardia (VT) who do not respond to standard treatments. However, the management of respiratory motion during treatment remains a challenge. This study aimed to investigate the effect of abdominal compression (AC) on respiratory induced motion in the heart. Materials

Flera platser utmed den skånska kusten har idag problem med stranderosion som innebär att havet äter sig inåt land så att stränder och kustlandskap försvinner. När havet stiger förväntas stranderosionen att öka och även kust sträckor som idag inte har problem kan komma att drabbas. Då kustlinjen rör sig inåt land hotas bebyggelse, infra struktur och naturområden, samtidigt som översvämningsrisken Beach erosion is expected to increase as the sea level rises during the coming decades. A retreating coastline threat ens infrastructure, settlements, nature habitats, and at the same time increases the flood risk in low-lying areas. On the Swedish south coast, beach erosion is a problem at present likely to increase due to the sea level rise. For main taining the beaches and protecting the hinter

The landscape of healthcare is experiencing a digitalization shift, transferring many medical activities to the patients’ homes, a phenomenon commonly referred to as Hospital-at-Home. While Internet of Things (IoT) devices facilitate the building of such systems, there is a need for powerful middleware that encapsulates device-to-device communication, and enables the construction of user-friendly,

Background Direct cell reprogramming is characterized by the use of defined factors to rewire the transcriptional and epigenetic network of one cell-type into one of a different lineage. We have recently identified the transcription factors PU.1, IRF8, and BAFT3 (PIB) as sufficient to induce a type 1 conventional dendritic cell (cDC1) fate in both somatic and cancer cells.1,2 cDC1 is a rare dendri

Children with generalized anxiety disorder (GAD) are often described by their parents or teachers as "little adults, " in part because of the seemingly adult-like themes that populate their child's worries; for example, the health of family members or family finances and concerns about performance. Younger children may experience more vague worries of "something" bad happening to themselves, famil

Background: Studies have shown that ambient air pollution is linked to preeclampsia (PE), possibly via generation of oxidative stress in the placenta. Telomere length and mitochondrial DNA copy number (mtDNAcn) are sensitive to oxidative stress damage.Objective: To study the association between prenatal exposure to ambient nitrogen oxides (NOx, a marker for traffic-related air pollution), and PE,

Encounters between patients in homecare and nursing students are cultural events where students, in principle, are in unknown territory. This study illuminated how nursing students recount (inter)actions in social relations in Danish homecare settings, illustrated by students with a self-appointed immigrant background. The study consisted of semi-structured interviews with eight nursing students.

Background People living with serious respiratory illness experience a high burden of symptoms. This review aimed to determine whether multicomponent services reduce symptoms in people with serious illness related to respiratory disease. Methods Electronic databases were searched to identify randomised controlled trials (RCTs) evaluating multicomponent services that enrolled patients due to sympto

Background In adults with serious respiratory illness, fatigue is prevalent and under-recognised, with few treatment options. The aim of this review was to assess the impact of graded exercise therapy (GET) on fatigue in adults with serious respiratory illness. Methods Electronic databases were searched to identify randomised controlled trials (RCTs) testing GET (involving incremental increases in

Atrial fibrillation (AF) is a complex condition caused by various underlying pathophysiological disorders and is the most common heart arrhythmia worldwide, affecting 2 % of the European population. This prevalence increases with age, imposing significant financial, economic, and human burdens. In Europe, stroke is the second leading cause of death and the primary cause of disability, with numbers

Background: Ambulatory oxygen therapy is prescribed for patients with chronic lung diseases who experience exertional hypoxemia. However, available devices may not adequately meet user requirements, and their performance characteristics are heterogeneous. Objective: This study aims to identify devices available for delivery of ambulatory oxygen therapy, the technologies that they use to generate o

Plastic’s unique properties are vital for a sustainable future, but its excessive global use signifies consumer society’s wastefulness, often found in short-lived products. Plastic development has overlooked recycling needs, resulting in low material recycling due to a wide array of plastic types with varying additives, leading to recycling challenges. Research focused on thermoplastics aims to re