Filetype
The European Gaia astrometry mission is due for launch in 2011. Gaia will rely on the proven principles of the ESA Hipparcos mission to create an all-sky survey of about one billion stars throughout our Galaxy and beyond, by observing all objects down to 20 mag. Through its massive measurement of stellar distances, motions and multicolour photometry, it will provide fundamental data necessary for
Introduction: We investigate the risks of subsequent primary bone cancers after childhood and adolescent cancer in 12 European countries. For the first time, we satisfactorily address the risks beyond 40 years from diagnosis and beyond 40 years of age among all survivors.Methods: This largest-ever assembled cohort comprises 69 460 five-year survivors of cancer diagnosed before age 20 years. Standa
Immunoglobulins are the effector molecules of the adaptive humoral immune system. In a genome-wide association study of 19,219 individuals, we found 38 new variants and replicated 5 known variants associating with IgA, IgG or IgM levels or with composite immunoglobulin traits, accounted for by 32 loci. Variants at these loci also affect the risk of autoimmune diseases and blood malignancies and in
The onset of inflammation is associated with reactive oxygen species and oxidative damage to macromolecules like 7,8-dihydro-8-oxoguanine (8-oxoG) in DNA. Because 8-oxoguanine DNA glycosylase 1 (OGG1) binds 8-oxoG and because Ogg1-deficient mice are resistant to acute and systemic inflammation, we hypothesized that OGG1 inhibition may represent a strategy for the prevention and treatment of inflam
GALAH is a large-scale magnitude-limited southern stellar spectroscopic survey. Its second data release (GALAH DR2) provides values of stellar parameters and abundances of 23 elements for 342 682 stars (Buder et al.). Here we add a description of the public release of radial velocities with a typical accuracy of 0.1 km s -1 for 336 215 of these stars, achievable due to the large wavelength covera
Background: It is currently unknown whether ultra-processed foods (UPFs) consumption is associated with a higher incidence of multimorbidity. We examined the relationship of total and subgroup consumption of UPFs with the risk of multimorbidity defined as the co-occurrence of at least two chronic diseases in an individual among first cancer at any site, cardiovascular disease, and type 2 diabetes.
BACKGROUND: Observational studies have shown that women with an early menopause are at higher risk of stroke compared with women with a later menopause. However, associations with stroke subtypes are inconsistent, and the causality is unclear. METHODS AND RESULTS: We analyzed data of the UK Biobank and EPIC-CVD (European Prospective Investigation Into Cancer and Nutrition-Cardiovascular Diseases)
Immunoglobulin G (IgG) is the main isotype of antibody in human blood. IgG consists of four subclasses (IgG1 to IgG4), encoded by separate constant region genes within the Ig heavy chain locus (IGH). Here, we report a genome-wide association study on blood IgG subclass levels. Across 4334 adults and 4571 individuals under 18 years, we discover ten new and identify four known variants at five loci
Background: The genetic basis of lacunar stroke is poorly understood, with a single locus on 16q24 identified to date. We sought to identify novel associations and provide mechanistic insights into the disease. Methods: We did a pooled analysis of data from newly recruited patients with an MRI-confirmed diagnosis of lacunar stroke and existing genome-wide association studies (GWAS). Patients were
Interactions between host and gut microbial communities are modulated by diets and play pivotal roles in immunological homeostasis and health. We show that exchanging the protein source in a high fat, high sugar, westernized diet from casein to whole-cell lysates of the non-commensal bacterium Methylococcus capsulatus Bath is sufficient to reverse western diet-induced changes in the gut microbiota
BACKGROUND: Alcohol is an established risk factor for several cancers, but modest alcohol-cancer associations may be missed due to measurement error in self-reported assessments. Biomarkers of habitual alcohol intake may provide novel insight into the relationship between alcohol and cancer risk.METHODS: Untargeted metabolomics was used to identify metabolites correlated with self-reported habitua
BACKGROUND AND AIMS: Atherosclerosis is a lipid-driven chronic inflammatory disorder of the arteries, and monocytes and macrophages play a central role in this process. Within the atherosclerotic lesion, macrophages can scavenge modified lipids and become the so-called foam cells. We previously reported that the epigenetic enzyme Kdm6b (also known as Jmjd3) controls the pro-fibrotic transcriptiona
BACKGROUND: Lymphatic disorders such as protein-losing enteropathy, plastic bronchitis, and chylothorax are important complications of the Fontan circulation and ultimately result in an increased risk of early death. Several European centers are now performing lymphatic procedures. The aim of this study is to map the extent of these lymphatic disorders and treatments provided across European pedia
We present a detailed analysis of HARPS-N radial velocity observations of K2-100, a young and active star in the Praesepe cluster, which hosts a transiting planet with a period of 1.7 d. We model the activity-induced radial velocity variations of the host star with a multidimensional Gaussian Process framework and detect a planetary signal of 10.6 ± 3.0 m s−1, which matches the transit ephemeris,
Melén Fäldt_Larsson The 2nd EuroSoTL conference, June 8-9 2017, Lund, Sweden Exploring a positive approach in facilitating teachers personal and professional development M. Melén Fäldt and S. Larsson, Kristianstad University, Sweden ABSTRACT: This presentation will reflect on experiences from the perspective of two education developers in an ongoing teacher development project within the Nurse Edu
https://konferens.ht.lu.se/fileadmin/_migrated/content_uploads/Mele__n_Fa__ldt_Larsson.pdf - 2026-05-04
6 Vocabularies of Reason 2025 Pufendorf Lectures Lund University Lecture II Logic and the Structure of Reasons I. Three Versions of a Basic Discursive Bipolarity In my first lecture I introduced the concept of reason relations of implication and incompatibility, motivated by Harman’s argument for the need to distinguish such rational relations from inferential practices. I showed that such consequ
https://www.fil.lu.se/fileadmin/user_upload/pufendorf/Files/Lecture_2.pdf - 2026-04-14
() Bottom-Up Architectures Bo Bernhardsson and K. J. ÃĚstrÃűm Department of Automatic Control LTH, Lund University Bo Bernhardsson and K. J. ÃĚstrÃűm Bottom-Up Architectures Bottom-Up Architectures 1 Introduction 2 Basic Architectures 3 Large Parameter Variations 4 Otto J. M. Smith’s Specials 5 Miscellaneous 6 Soft Computing 7 Summary Theme: Brick by brick. Bo Bernhardsson and K. J. ÃĚstrÃűm Botto
https://www.control.lth.se/fileadmin/control/Education/DoctorateProgram/ControlSystemsSynthesis/2016/BottomUp.pdf - 2026-05-05
1 Visser’s Generalization and the c-command condition on Control Jacek Witkoś (wjacek@amu.edu.pl) & Sylwiusz Żychliński (sylwiusz@amu.edu.pl) 1. Introduction The major focus of this presentation is Visser’s Generalization (Visser 1973), an observation that holds of very similar terminal strings in (1a-b), where the passive transformation is compatible with an Object Control predicate (cf. 2b) but
https://konferens.ht.lu.se/fileadmin/user_upload/sol/ovrigt/konferens_glow36/Handouts_and_Presentations/Witkos.pdf - 2026-05-04
