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Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer

BACKGROUND: Treatment of newly diagnosed advanced-stage ovarian cancer typically involves cytoreductive surgery and systemic chemotherapy. We conducted a trial to investigate whether the addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery would improve outcomes among patients who were receiving neoadjuvant chemotherapy for stage III epithelial ovarian ca

Att fabulera genom research : hur fantastikförfattare söker information i sitt skönlitterära skrivande för barn och unga

The aim of this master’s thesis is to examine how fiction authors seek information in their writing, which still is a vastly under-researched subject within Library and Information Science. Why then are there so few of us in this discipline who ask themselves which information behaviour and information needs that exist among the ones writing the literature filling our libraries? This study was car

Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

Background Quinquennial overviews (1985-2000) of the randomised trials in early breast cancer have assessed the 5-year and 10-year effects of various systemic adjuvant therapies on breast cancer recurrence and survival. Here, we report the 10-year and 15-year effects. Methods Collaborative meta-analyses were undertaken of 194 unconfounded randomised trials of adjuvant chemotherapy or hormonal ther

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AI och akademiker – förhoppningar och utmaningar i en föränderlig tid AI och akademiker – förhoppningar och utmaningar i en föränderlig tid © Jenny Grensman och Jenny Wahlbäck och Saco 2023 www.saco.se Sammanfattning Undersökningen ”AI och akademiker” som Novus gjort på uppdrag av Saco visar att en stor del av akademikerna har en positiv eller neutral inställning till en framtida användning av AI

https://www.saco.se/globalassets/bilder-video-och-dokument/amnesomraden/ai/2023-ai-och-akademiker.pdf - 2026-05-05

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Riktlinjer för examination för utbildning på grundnivå och avancerad nivå Beslut i fakultetsstyrelsens arbetsutskott 2024-12-11 Ikraftträdandedatum 2025-01-13 Dnr STYR 2024/1487 Postadress Box 192, 22100 LUND Besöksadress LUX Helgonavägen 3, LUND E-post http://www.ht.lu.se/person/LisaHetherington/ Webbadress http://www.ht.lu.se Innehåll Inledning....................................................

https://www.ht.lu.se/fileadmin/user_upload/ht/Riktlinjer_f%C3%B6r_examination_f%C3%B6r_utbildning_p%C3%A5_grundniv%C3%A5_och_avancerad_niv%C3%A5_20241211.pdf - 2026-05-04

Inflation, indexering och offentliga trygghetsförsäkringar

Inflation, indexering och offentliga trygghetsförsäkringar Inflation, indexering och offentliga trygghetsförsäkringar Inflation, indexering och offentliga trygghetsförsäkringar Thomas Andrén © Thomas Andrén och Saco 2023 www.saco.se http://www.saco.se/ 3 Inledning Sedan mitten av 1990-talet fram till 2021 låg den svenska inflationen på en relativt låg och stabil nivå, med långa perioder under Riks

https://www.saco.se/contentassets/1c033cf7e6554dac983c5774aa911e01/2023-inflation-indexering-och-offentliga-trygghetsforsakringar.pdf - 2026-05-04

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The three-gender system in two varieties of Jämtlandic∗ Briana Van Epps, Lund University Abstract. This is a study on the gender system of the Swedish dialect spoken in Jämtland, a province in northern Sweden. The Jämtlandic dialect preserves to a large extent the three- gender system that was present in Old Swedish. The three-gender system manifests in anaphoric pronouns and as agreement in the n

https://projekt.ht.lu.se/fileadmin/_migrated/content_uploads/Van_Epps._The_Three-gender_system.pdf - 2026-05-04

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Sida Decentralised Evaluation Evaluation of Programme Work Methods of The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Final Report Nicklas Svensson Lone Lindholt Henrik Alffram 2018:5 Evaluation of Programme Work Methods of The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Final Report February 2018 Nicklas Svensson Lone Lindholt Henrik Alffram Sida Decentrali

https://rwi.lu.se/app/uploads/2019/02/Final-report-global-review-work-methods-pub-version.pdf - 2026-05-04

Generalizability of a Diabetes-Associated Country-Specific Exploratory Dietary Pattern Is Feasible Across European Populations

BACKGROUND: Population-specificity of exploratory dietary patterns limits their generalizability in investigations with type 2 diabetes incidence. OBJECTIVE: The aim of this study was to derive country-specific exploratory dietary patterns, investigate their association with type 2 diabetes incidence, and replicate diabetes-associated dietary patterns in other countries. METHODS: Dietary intake da

Body size and risk of colon and rectal cancer in the European prospective investigation into cancer and nutrition (EPIC)

Background: Body weight and body mass index (BMI) are positively related to risk of colon cancer in men, whereas weak or no associations exist in women. This discrepancy may be related to differences in fat distribution between sexes or to the use of hormone replacement therapy (HRT) in women. Methods: We used multivariable adjusted Cox proportional hazards models to examine the association betwee

Thyroid-Stimulating Hormone, Thyroglobulin, and Thyroid Hormones and Risk of Differentiated Thyroid Carcinoma: The EPIC Study

Background Increased levels of thyroglobulin (Tg) and thyroid-stimulating hormone (TSH) are associated with differentiated thyroid carcinoma (TC) risk, but strong epidemiological evidence is lacking. Methods Three hundred fifty-seven incident TC case patients (n = 300 women and 57 men; mean age at blood collection = 51.5 years) were identified in the EPIC cohort study and matched with 2 (women) or

International Epidemiology of Child and Adolescent Psychopathology II: Integration and Applications of Dimensional Findings From 44 Societies

Objective: To build on Achenbach, Rescorla, and Ivanova (2012) by (a) reporting new international findings for parent, teacher, and self-ratings on the Child Behavior Checklist, Youth Self-Report, and Teacher's Report Form; (b) testing the fit of syndrome models to new data from 17 societies, including previously underrepresented regions; (c) testing effects of society gender, and age in 44 societ

UNITY: A low-field magnetic resonance neuroimaging initiative to characterize neurodevelopment in low and middle-income settings

Measures of physical growth, such as weight and height have long been the predominant outcomes for monitoring child health and evaluating interventional outcomes in public health studies, including those that may impact neurodevelopment. While physical growth generally reflects overall health and nutritional status, it lacks sensitivity and specificity to brain growth and developing cognitive skil

Genomic and transcriptomic features of androgen receptor signaling inhibitor resistance in metastatic castration-resistant prostate cancer

BACKGROUNDAndrogen receptor signaling inhibitors (ARSIs) have improved outcomes for patients with metastatic castration-resistant prostate cancer (mCRPC), but their clinical benefit is limited by treatment resistance.METHODSTo investigate the mechanisms of ARSI resistance, we analyzed the whole-genome (n = 45) and transcriptome (n = 31) sequencing data generated from paired metastatic biopsies obt

Systematic review and meta-analysis of humoral immunity proteins and mortality in sepsis

Purpose: Humoral immunity proteins—immunoglobulins, complement proteins, and antimicrobial peptides—have key antimicrobial and immunomodulatory functions in sepsis. We hypothesised that their circulating levels are lower in non-survivors, potentially resulting in impaired bacterial clearance and persistent or recurrent infections. Methods: We performed a systematic review and meta-analysis evaluat

Meat, fish, and colorectal cancer risk: The European prospective investigation into cancer and nutrition

Background. Current evidence suggests that high red meat intake is associated with increased colorectal cancer risk. High fish intake may be associated with a decreased risk, but the existing evidence is less convincing. Methods: We prospectively followed 478040 men and women from 10 European countries who were free of cancer at enrollment between 1992 and 1998. Information on diet and lifestyle w

Localized exocytosis of primary (lysosomal) granules during phagocytosis: role of Ca2+-dependent tyrosine phosphorylation and microtubules.

The uptake and killing of bacteria by human neutrophils are dependent on the fusion of secretory granules with forming phagosomes. The earliest component of exocytosis was found to precede phagosome closure, so that granular membrane constituents were detectable on the plasmalemma. We show that during phagocytosis of IgG-opsonized particles, this early secretory response is highly polarized in the

The pTalpha promoter and enhancer are direct targets for transactivation by E box-binding proteins.

The pre-Talpha (pTalpha[?]) gene encodes a protein that forms the pre-TCR together with the newly expressed TCR beta chain during a defined stage of early T cell development. The restricted expression of this gene has been suggested to depend on a promoter and an enhancer element containing E boxes, which are potential binding sites for basic helix-loop-helix (bHLH) proteins. We here report that i