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The present work describes the numerical modeling of medium-speed marine engines, operating in a fumigated dual-fuel mode, i.e. with the second fuel injected in the ports. This engine technology allows reducing engine-out emissions while maintaining the engine efficiency and can be fairly easily retrofitted from current diesel engines. The main premixed fuel that is added can be a low-carbon one a
In a Northern country such as Sweden, energy use in the home may be reduced by 20% through changes in behaviour. However, little is known about how households respond to policy instruments encouraging such change or to what degree this in turn may affect the workload of women and men in such communities. The current study presents findings from interviews with 30 households in Sweden that particip
Smad5 is known to transduce intracellular signals from bone morphogenetic proteins (BMPs), which belong to the transforming growth factor-beta (TGF-beta) superfamily and are involved in the regulation of hematopoiesis. Recent findings suggest that BMP4 stimulates proliferation of human primitive hematopoietic progenitors in vitro, while early progenitors from mice deficient in Smad5 display increa
Label-free LC-MS methods are attractive for high-throughput quantitative proteomics, as the sample processing is straightforward and can be scaled to a large number of samples. Label-free methods therefore facilitate biomarker discovery in studies involving dozens of clinical samples. However, despite the increased popularity of label-free workflows, there is a hesitance in the research community
Calcitonin gene-related peptide (CGRP) research was initiated by Poyner et al.,(1) who found that the calcitonin gene encodes the 37-amino acid neuropeptide CGRP in neuronal tissue. Within months, the Lund group produced antibodies toward α-CGRP and developed sensitive methods to study the role of this peptide in the cranial circulation. Intracranial vessels and the trigeminal ganglion harbor this
Sustainable development requires coordination among multi-level actors to achieve set targets, with networks playing a key role in sharing knowledge and fostering collective actions. These networks’ success hinges on member engagement, but since participation is voluntary, members choose their level of involvement. Despite the importance, factors influencing network engagement remain rather scarce
Granule neurons of the dentate gyrus (DG) of the hippocampus undergo continuous renewal throughout life. Among cell cycle regulators, cyclin-dependent kinase 2 (Cdk2) is considered as a major regulator of S-phase entry. We used Cdk2-deficient mice to decipher the requirement of Cdk2 for the generation of new neurons in the adult hippocampus. The quantification of cell cycle markers first revealed
Revised simulation theory (Goldman, 2006) allows mental state attributions containing some or all of the attributor’s genuine, non-simulated mental states. It is thought that this gives the revised theory an empirical advantage, because unlike theory theory and rationality theory, it can explain egocentric bias (the tendency to over attribute ones’ own mental states to others). I challenge this vi
Since the economic reforms in 1978 the Chinese economy has shown remarkable growth rates. The countries in East Asia all had very high growth rates before they were hit by the economic crisis in 1997. Could the same thing happen to China? The aim of the thesis is to investigate if China is heading for an economic crisis. Based on theories and empirical studies of other economic crises we study the
With growing concern over organised crime in Sweden, increased attention has been directed towards children's involvement in escalating violence. Children are portrayed both as victims of coercion and as voluntary participants, reflecting a dual approach in governmental policy. This study investigates how the issue of children's involvement in criminal activities is problematised in three
Idag utförs en betydande del av den ledande humanistiska och teologiska forskningen i vetenskapliga miljöer vid sidan om traditionella ämnesdisciplinära och organisatoriska indelningar. HT-fakulteterna har därför infört en satsning på forskningsplattformar för att sådana gränsöverskridande forskningsmiljöer ska ges förutsättningar att bygga upp och utveckla långsiktiga interdisciplinära samarbetenToday a large amount of research within the humanities and theology is conducted in academic environments outside of traditional disciplinary and organisational units. The Joint Faculties of Humanities and Theology are promoting the establishing and development of long-term interdisciplinary collaborations by giving monetary support to five research platforms chosen by an external expert jury.
Geografiska aspekter på kulturella, ekonomiska och ekologiska förlopp på global, nationell, regional och lokal nivå. Kultur- och bebyggelselandskapets historia, studier av urbaniserings- och befolkningsfrågor i modern tid. Lokaliseringsfrågor, kommunikationer och organisationsformer inom svenskt näringsliv och offentlig förvaltning. Organisationsformer, landsbygdsutveckling samt allmänna utvecklin
Due to social and environmental crises, the concept of sustainability has grown in importance in our society over the past years. Things are changing, even in the financial industry. From the perspective of investors, the general public, and enterprises, Corporate Social Responsibility and the creation of sustainable value are becoming more and more significant. One of the most cutting-edge tools
The aggregating proteoglycans (aggrecan, versican, neurocan, and brevican) are important components of many extracellular matrices. Their N-terminal globular domain binds to hyaluronan, but the function of their C-terminal region containing a C-type lectin domain is less clear. We now report that a 90-kDa protein copurifies with recombinant lectin domains from aggrecan and versican, but not from t
