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An indirect 125I-labeled protein A assay for detection of cell surface-bound rat immunoglobulins is presented. The assay is quantitative and rapid and detects as little as 1 ng of cell surface-bound Ig. It discriminates between antibodies belonging to different IgG subclasses, IgM and IgA. We describe the production and specificity control of the reagents used and show that the test can be used fo
The aim of this study was to describe first-time mothers' views of satisfaction with their first encounter with the nurse, in order to investigate differences between home visits and clinic visits and between high/middle and low socioeconomic classification (SEC). A nation-wide postal questionnaire sent to 800 first-time mothers yielded the data for statistical analysis. Data were collected using
OBJECTIVES This study describes changes in high-frequency QRS components (HF-QRS) during percutaneous transluminal coronary angioplasty (PTCA) and compares the ability of these changes in HF-QRS and ST-segment deviation in the standard 12-lead electrocardiogram (ECG) to detect acute coronary artery occlusion. BACKGROUND Previous studies have shown decreased HF-QRS in the frequency range of 150–
The default response of the intestinal immune system to most antigens is the induction of immunological tolerance, which is difficult to reconcile with the constant exposure to ligands for TLR and other pattern recognition receptors. We showed previously that dendritic cells (DC) from the lamina propria of normal mouse intestine may be inherently tolerogenic and here we have explored how this migh
Factor I (FI) is the major complement inhibitor that degrades activated complement components C3b and C4b in the presence of specific cofactors. Complete FI deficiency results in secondary complement deficiency due to uncontrolled spontaneous alternative pathway activation. In this study we describe two unrelated patients with complete FI deficiency and undetectable alternative complement pathway
Static light scattering (SLS) combined with structure-based Monte Carlo (MC) simulations provide new insights into mechanisms behind anisotropic, attractive protein interactions. A nonmonotonic behavior of the osmotic second virial coefficient as a function of ionic strength is here shown to originate from a few charged amino acids forming an electrostatic attractive patch, highly directional and
Sexual selection against immigrants is a mechanism that can regulate premating isolation between populations but, so far, few field studies have examined whether males can discriminate between immigrant and resident females. Males of the damselfly Calopteryx splendens show mate preferences and are able to force pre-copulatory tandems. We related male mate responses to the ecological characteristic
The distinction between thermodynamic and kinetics in cellulose dissolution is seldom considered in the literature. Therefore, herein an attempt to discuss this topic and illustrate our hypotheses on the basis of simple experiments was made. It is well-known that cellulose can be dissolved in a aqueous sodium hydroxide (NaOH/H2O) solvent at low temperature but it is here shown that such an alkalin
Some concerns still have not been resolved about the long-term safety of drug-eluting stents (DES) in patients with acute STEMI.
Earlier work has shown that pre-B cells can be converted into macrophages by the transcription factor CCAAT/enhancer binding protein a at very high frequencies. Using this system, we performed a systematic analysis of whether during transdifferentiation the cells transiently reactivate progenitor-restricted genes or even retrodifferentiate. A transcriptome analysis of transdifferentiating cells sh
Joseph Beuys. Fat and felt. A critical essay. The extremely singular materials fat and felt for use in art, have an entirely dominating role in a long series of Joseph Beuys’ (1921-1986) most important work. They are found both in single works of art as well as in installations and happenings from the beginning of the 1960s and up to the end of the artist’s life. This essay deals with the artist’
Syftet med denna studie är att undersöka vad som får elever att börja spela brassinstrument och vilka faktorer som motiverar dem till att fortsätta på Musik- och Kulturskolan. Bakgrunden till studien är att antalet elever på brassinstrumenten i Musik- och Kulturskolorna har minskat i Sverige under lång tid. Data består av gruppintervjuer med 11 elever i tre åldersbaserade grupper. Resultatet viThe purpose of this study is to investigate what motivates students to begin playing a brass instrument and the factors that motivate them to continue in the Community School of Music and Arts. The background for this study is that the number of students on brass instruments in the Community Schools of Music and Arts in Sweden has been decreasing for many years. Data collection was performed thro
The phenomenon deepfake was created in 2017 and has since developed and received a lot of attention, especially in pornography thus the absolute majority of all deepfakes on the internet are of pornographic content, with 90% of those who are exposed to deepfakes are woman. The purpose of this essay is to investigate young women’s awareness of deepfakes as well as how the phenomenon used in porn co
In recent decades, digital markets have become one of the most significant and debated areas not only in the world of politics and economics, but also in legal doctrine and practice. The rapid evolution of dynamic digital markets, coupled with the outline of the Digital Markets Act (DMA), has led to significant debate within EU competition law on the appropriate balance between ex-ante and ex-post
The realisation that climate change will have serious effects on human life has activated the wider human rights community, which is now searching for an entrance into the global issue of our time. So far, most efforts by human rights practitioners have been concentrated on the overarching problem of global injustice, which relates to the right to development. However, in estimating the effects
The increasing significance of social economy as a concept is linked to general global processes such as the crisis of the welfare state, neoliberal globalization, anti-bureaucracy tendencies and decentralization, but also to a growing political interest in human rights and social development. In Sweden the idea of the social economy generates wide support within civil society as well as within th
In 2006, a cross-sectional survey of 384 randomly selected houses within a community-based follow-up study was conducted to assess the human T-cell lymphotropic virus (HTLV) prevalence in Bissau. Changes in prevalence and incidence rates were assessed based on a similar survey carried out 10 years earlier. The prevalence of HTLV-1 declined significantly from 3.5% in 1996 to 2.3% in 2006. The incid
