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The present contribution describes some simulations of the observation of binaries with GAIA. The results do not differ fundamentally from earlier estimates, e.g. in GAIA's Concepts and Technology Study Report (ESA-2000-SCI-4), but they are based on more realistic assumptions and much more extensive numerical work.
Popular Abstract in Swedish MHC upptäcktes för 60 år sedan då George Snell konstaterade att möss som var genetiskt lika inte stötte bort transplanterad hud medan genetiskt olika möss gjorde det. Men det var inte förrän långt senare som man insåg vilken roll som MHC spelar i immunförsvaret hos alla vertebrater. Sedan ett par decennier tillbaka är detta ett välstuderat område speciellt hos människanIn birds the major histocompatibility complex (MHC) organization differs both among and within orders. Galliformes often have simple arrangements with few transcribed MHC genes whilst many songbirds (Passeriformes) have a complex arrangement with many MHC genes and also presence of pseudo-genes. In this thesis I have partly characterized MHC class I in house sparrows (Passer domesticus), sequencin
The mechanical design of the EUROBALL neutron wall and neutron detectors, and their performance measured with a Cm-246,Cm-248 fission source are described. The array consists of 15 pseudohexaconical detector units subdivided into three, 149 mm high, hermetically separated segments and a smaller central pentagonal unit subdivided into five segments. The detectors are filled with Bicron BC501A liqui
We have identified a novel protein, Leprecan-like 1 (LEPREL1), with profound similarity to the Leprecan family of proteoglycans. The genomic organization of the Leprecan gene family was found to be highly conserved. Expression analysis shows that LEPREL1 is expressed in most tissues as a 3.4 kb transcript encoding an 80 kDa protein. A LEPREL1 specific antibody stains many cell types including adip
Retinitis Pigmentosa (RP) is a group of uncured retinal diseases with the world wide incidence of about 1/3500. In spite of the huge efforts in past years, the mechanisms underlying this type of hereditary blindness has not been elucidated and nor any effective treatment available. The rd1 mouse strain carries a mutation in ?-subunit of phosphodiesterase gene which hydrolyzes the cGMP and is need
The effect on haemostatic variables by dextran 70, enoxaparin and their combinations, given in doses of 500 ml i.v. and 40 mg s.c. respectively, was studied in a randomised cross-over fashion in twelve healthy male volunteers. Antifactor-IIa activity, antifactor-Xa activity, APTT, factor VIII, vWF, bleeding time and blood counts were analysed over a 24-h period. Dextran alone did not affect antifa
Popular Abstract in Swedish Parkinsons sjukdom (PS) karaktäriseras av långsam celldöd i hjärnan och gradvis uppträder minskad rörlighet och muskelstelhet som mest framträdande symptom. PS drabbar ungefär 0.1% av befolkningen, och inträder oftast i femtio- till sextioårsåldern. Varför sjukdomen uppkommer är till stor del okänt, men man vet att de dopamin producerande cellerna i mitthjärnan (särskilParkinson's disease (PD) is a common neurodegenerative disorder characterized by motor deficits. Levodopa treatment provides marked symptomatic relief. However, within 5-10 years after the start of Levodopa treatment, most PD patients display a gradual loss of drug efficacy. Importantly, the neuropathology of PD is dominated by a marked loss of dopaminergic neurons located in the substantia nigra.
The kinetic properties of dUTPase from equine infectious anemia virus (EIAV) were investigated. KM (1.1 [plusmn] 0.1 [mu ]M) and kcat (25 s[minus ]1) were found to be independent of pH in the neutral pH range. Above pH 8.0, KM increases slightly. Below pH 6.0, the enzyme is rapidly deactivated. Detergent was found to enhance activity, leaving KM and kcat unaffected. Compared to the Escherichia col
We have fit synthetic visibilities from three-dimensional ((COBOLD)-B-5+PHOENIX) and one-dimensional (PHOENIX, ATLAS 12) model stellar atmospheres of Procyon (F5 IV) to high-precision interferometric data from the VLT Interferometer (K band) and from the Mark III interferometer (500 and 800 nm). These data sets provide a test of theoretical wavelength-dependent limb-darkening predictions. The work
Autoimmune type 1 diabetes is strongly associated with a number of immune abnormalities that manifest themselves before and at the time of clinical diagnosis. The clinical onset is associated with a major loss of the pancreatic islet beta cells. Insulin treatment is the only treatment option since numerous trials with agents that suppress or modulate immune function have failed to preserve beta ce
High-spin states in the proton-rich nucleus V-45 have been identified for the first time. A comprehensive gamma-ray decay scheme has been established following an experiment performed at the Vivitron accelerator at IReS Strasbourg by using the Euroball gamma-ray detector array coupled to the Neutron Wall and Euclides detector arrays. The natural (negative-) parity scheme is identified up to the f(
High-spin states of the nucleus Lu-163 have been populated through the fusion-evaporation reaction La-139(Si-29, 5n) with a beam energy of 157 MeV. In addition to the two lowest excited triaxial strongly deformed (TSD) bands, recently interpreted as one- and two-phonon wobbling excitations, a third excited TSD band has been firmly established decaying to the yrast TSD band. The assignment of this
This thesis concerns the prediction of the fluid mechanical conditions in some specific large vessels in the human body. Large vessels are special in the way that the Reynolds number is relatively high and in the case of arteries the flow is pulsatile. The aim is to contribute to the knowledge of flow patterns in large vessels, and ways to predict and measure fluid mechanical parameters such as sh
In summer 1987 most of the multibody dynamics community met at the JPL, Pasadena, to discuss the needs and the open problems in multibody system simulation, especially for space applications. P. W. Likins stated in his survey [16]: “Computational questions focused initially on the selection of subroutines for numerical integration, matrix inversion, or eigensystem analysis,and lately have shifted
