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1,2-Addition of 3,4-methylenedioxymagnesium bromide to 2-(R) and (S)-benzyloxy-2,5-dihydro-4-furancarboxaldehyde, followed by oxidation, gave the title ketones (3r and 3s). Conjugate addition of the anions of 3,4,5-trimethoxy- and 3,4-methylenedioxybenzaldehyde diphenylthioacetal to 3r and 3s and Raney-nickel desulfurisation, followed by hydrogenolysis under various conditions, gave the title lign
Background: Primary spinal tumors are rare. Symptoms depend on the size and location of the tumor.Case description: A patient presented with a rare clinical finding, Brown-Séquard syndrome. The symptoms were caused by an extramedullary tumor compressing on the thoracic spinal cord. Pathologic examination showed cavernous hemangioma with growth both intradurally and extradurally.Conclusions: This i
BACKGROUND: Owing to the wide spread perception of a possible benefit from paclitaxel in the second-line situation the Nordic Gynecologic Oncology Group (NGOG) conducted two prospective phase II studies of paclitaxel single agent treatment (175 mg/m2, three-hour i.v. infusion with standard pre-medication every third week) in patients with relapsing or progressing epithelial ovarian cancer followin
BACKGROUND: Most cerebral palsy (CP) cases have an unexplained etiology, but a role for environmental exposures has been suggested. One purported environmental risk factor is exposure to endocrine-disrupting pollutants specifically per- and polyfluoroalkyl substances (PFAS).OBJECTIVES: We investigated the association between prenatal PFAS exposures and CP in Swedish children.METHODS: In this case-
Evaluating the subground properties during the initial stage of a construction of building is important in order to estimate the suitability of soil quality to the technical requirements of bearing capacity, resistance to stress, and strength. This study presented the evaluation of the geotechnical properties of soil intended for the construction of Max IV facility of Lund University, performed in
Improved water, sanitation and hygiene (WASH) are significant in preventing diarrhea morbidity and mortality caused by protozoa in low- and middle-income countries. Due to the intimate and complex relationships between the different WASH components, it is often necessary to improve not just one but all of these components to have sustainable results. The objective of this paper was to review the c
Apolipoprotein M (ApoM) is a sphingosine 1-phosphate (S1P) carrier involved in the regulation of S1P. Signaling pathways involving sphingosine kinases (SphKs) and S1P-S1P receptors (S1PRs) play important roles in the oncogenesis of multiple cancers including non-small cell lung cancer (NSCLC). In the present study we have clarified the potential roles of ApoM on the oncogenesis process of NSCLC ce
The production of strange hadrons (KS0 , Λ, Ξ±, and Ω±), baryon-to-meson ratios (Λ/ KS0 , Ξ/ KS0 , and Ω/ KS0), and baryon-to-baryon ratios (Ξ/Λ, Ω/Λ, and Ω/Ξ) associated with jets and the underlying event were measured as a function of transverse momentum (p T) in pp collisions at s = 13 TeV and p Pb collisions at sNN = 5.02 TeV with the ALICE detector at the LHC. The inclusive production of the
Den boreala regionen innehåller 40% av jordens kol (C) som lagras i vegetation och mark med sina skogar som står för nästan 30% av den terrestra C sänkan. Boreala skogar upplever några av de snabbaste hastigheterna för klimatuppvärmning och ökningar i brandaktivitet, vilket hotar att släppa ut stora mängder av deras C reserver till atmosfären. Även om klimat och skogsbränder har stark kontroll öveThe boreal region contains 40% of the earth’s carbon (C) that is stored in vegetation and soils with its forests accounting for almost 30% of the terrestrial C sink. Boreal forests are experiencing some of the most rapid rates of climatic warming and increases in fire activity, threatening to release large amounts of their dense C reserves to the atmosphere. While climate and wildfire place strong
The Kalabagh strike–slip fault, which is characterized by right-lateral movement, is part of the northwestern Himalayan foreland fold and thrust belt in Pakistan. This structure marks the western and eastern terminations of the Salt Range and Surghar Ranges, respectively. No significant (>M6) earthquakes have been reported along the Kalabagh Fault in recent decades. Here, we take advantage of spac
Inflammatory leiomyosarcoma (ILMS), defined as “a malignant neoplasm showing smooth muscle differentiation, a prominent inflammatory infiltrate, and near-haploidization”, is a very rare soft tissue tumor with a generally favorable prognosis. The morphologic features of “histiocyte-rich rhabdomyoblastic tumor” (HRRMT) are similar to those of ILMS, although this lesion shows by definition a skeletal
We explore the interplay of electron-electron correlations and surface effects in the prototypical correlated insulating material, NiO. In particular, we compute the electronic structure, magnetic properties, and surface energies of the (001) and (110) surfaces of paramagnetic NiO using a fully charge self-consistent DFT+ dynamical mean-field theory method. Our results reveal a complex interplay b
Background: Although it has been established that low socioeconomic status is linked to increased risk of death after stroke, the mechanisms behind this link are still unclear. In this study we aim to shed light on the relationship between income level and survival after stroke by investigating the extent to which differences in stroke severity account for differences in survival. Methods: The stu
This chapter discusses three comparative projects that were all, at least partially, created through the replication of research across the Mistra Urban Futures cities. A typology of six possible models was developed, illustrating how comparative transdisciplinary knowledge co-production could take place across multiple cities, and the second of these approaches was identified as “local projects r
Syftet med uppsatsen är att bidra till en reflektion och diskussion kring meningsbegreppet i dagens humaniora, och mera specifikt inom dess posthumanistiska rörelse. Min tes är att meningsbegreppet är teoretiskt underutvecklat inom posthumanismen i allmänhet, och att det i själva verket använder sig av en Deleuziansk förståelse av mening utan att göra det explicit eller reflektera närmare över d
Non-human animals are often excluded from contemporary political theories, much to their detriment in terms of welfare and protection. The ‘political turn’ is a subset of animal ethicists concerned with moving beyond motivating moral status and instead discussing the politics of a shared human-animal society. This thesis evaluates Philip Pettit’s neo-republicanism as a theoretical framework for a
This study examines the long-term abnormal returns of stocks following Initial Public Offerings (IPOs) and Seasoned Equity Offerings (SEOs) on the Swedish and American markets from January 2000 to March 2021. Additionally, it examines the differences between Swedish and American companies and investigates factors influencing these disparities, focusing on the importance of market capitalization at
In recent years, it has been reported that sex education in Swedish schools has been lacking, and, thus, in 2022, new guidelines for sex education were implemented (sexuality consent and relationships, SCaR). This change meant that sex education is part of all curricula and that the responsibility to teach it rests on teachers of all subjects. With the theory of language as reproducing and changin
