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Primary Systemic Vasculitides [PSV: Wegener's granulomatosis (WG), microscopic polyangiitis (MPA), Churg-Strauss syndrome (CSS) and polyarteritis nodosa (PAN)] are rare systemic diseases of unknown etiology; if untreated, they are associated with high morbidity and mortality rates. Changes in the classification and diagnostic improvements during the last decades have increased reported prevalence
A central point of departure for this socio-legal study about online hate crimes concerns the significance of analysing and understanding social norms in relation to these crimes on the Internet. This is of importance not least when one approaches the issue of how law and the legal system may contribute towards positive developments in this field and prevent hate crimes. It is apparent that law an
Parents influence the development of their offspring in many ways beyond the transmission of DNA. This includes transfer of epigenetic states, nutrients, antibodies and hormones, and behavioural interactions after birth. While the evolutionary consequences of such non-genetic inheritance are increasingly well understood, less is known about how inheritance mechanisms evolve. Here, we present a sim
Stroke and in this case cerebral infarction affects 20 million people each year and five million of them die. In Sweden 30-35000 people will be affected and one of three of them will be severely disabled. In addition, one of six will suffer a new stroke within six years. The cause of stroke is usually a vessel in the brain that is blocked, resulting in massive neuronal cell death. Since treatment
Purpose – The purpose of this paper is to provide a paradigmatic reflection on theoreticalapproaches recently identified in logistics and supply chain management (SCM); namely complex adaptive systems and complexity thinking, and to compare it to the dominant approach in logistics and SCM research, namely the systems approach. By analyzing the basic assumptions of the three approaches, SCM and log
Life expectancy is increasing in most developed countries, in part due to improved socioeconomic conditions and in part to advances in healthcare. It is widely acknowledged that the promotion of healthy ageing by delaying, minimizing or preventing disabilities or diseases is one of the most important public health objectives in this century. In contrast to the menopausal transition in females, we
Blood coagulation has a Janus-faced role in infectious diseases. When systemically activated, it can cause serious complications associated with high morbidity and mortality. However, coagulation is also part of the innate immune system and its local activation has been found to play an important role in the early host response to infection. Though the latter aspect has been less investigated, phy
The iterative quasiparticle random-phase approximation (QRPA) method we previously developed [Phys. Rev. C 81, 034312 (2010); 86, 024303 (2012); 86, 014307 (2012)] to accurately calculate properties of individual nuclear states is extended so that it can be applied for nuclei with odd numbers of neutrons and protons. The approach is based on the proton-neutron QRPA (pnQRPA) and uses an iterative n
Background: An increasing numbers of deaths occur in nursing homes. Knowledge of the course of development over the years in death rates and predictors of mortality is important for officials responsible for organizing care to be able to ensure that staff is knowledgeable in the areas of care needed. The aim of this study was to investigate the time from residents' admission to Icelandic nursing h
In this review, we summarize a series of experimental studies of the swelling of zwitterionic lamellar phospholipid and phospholipid-cholesterol systems using a novel double twin calorimeter. With this method, one can obtain simultaneous measures of the partial molar free energy and the partial molar enthalpy, and the experimental studies thus provide a complete thermodynamic characterization of t
High-spin states have been studied in Pr-135(59), populated through the Cd-116(Na-23,4n) reaction at 115 MeV, using the Gammasphere gamma-ray spectrometer. The negative-parity yrast band has been significantly extended to spin similar to 45 (h) over bar and excitation energy 21.5 MeV, showing evidence for several rotational alignments. The positive-parity yrast band of Ce-135(58), populated throug
The article relates the concept of God's "plan" in Job 38:2 and 42:3 to similar concepts in earlier Ancient Near Eastern mythological literature, especially the term niklātu ("wise, ingenious things") used in the Babylonian Enuma Elish to describe the actions of Marduk - both the battle against the chaos monster Tiamat and the creation of the earthly world. Parallels are also drawn to expressions
The complexing ability of the binary system trans-aconitic acid (H3L) with regard to Cd(II) and the crystal structures of the binary system Cd(II)-(H3L), [Cd3L2(H2O)(6)] n(1) and ternary systems of Cd(II)-(H3L)-Lewis base [Lewis base = 1,10-phenanthroline (2) and 2,2'-bipyridine (3)] have been determined. Compound I is a rare binodal four-connected three-dimensional (3D) metal-organic framework po
Coeliac disease (CD) is becoming a model for understanding the pathogenesis of autoimmune disorders. In CD, antibodies against transglutaminase 2 (TG2) and specific glutamine residues of gliadins have been identified. A similar situation is seen in rheumatoid arthritis with both anticitrullinated protein antibodies (ACPA) and auto-antibodies against the citrullinating enzyme, peptidylarginine deim
One of the major symptoms of the neurodegenerative condition Parkinson's disease (PD) is a slowness or loss of voluntary movement, yet frustratingly therapeutic strategies designed to restore movement can result in the development of excessive abnormal movements known as dyskinesia. These dyskinesias commonly develop as a result of pharmacotherapy in the form of L-DOPA administration, but have als
This paper investigates the distribution of embedded verb second in Faroese, Icelandic, Norwegian, and Swedish. Two conclusions can be drawn from the study. First, none of the Scandinavian languages can be said to display generalized embedded verb second across the board. There are varieties of Faroese and Icelandic that display restrictions of the kind found in the other Scandinavian languages. I
